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MIRAGE
Plasminogen activator inhibitor 1

Summary
UniProt ID
P05121
Gene Symbol
  • PAI1
  • PLANH1
  • SERPINE1
Gene ID
5054
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011385
GlyConnect
GlyGen
P05121
PubChem
P05121
The Human Metabolome Database
HMDBP01864
Re-Glyco
P05121
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Direct protein sequencing
  • Glycoprotein
  • Proteomics identification
  • Reference proteome
  • Secreted
  • Serine protease inhibitor
  • Signal
Gene Ontology (GO)
Displaying all 8 entries
GO Term
extracellular region
extracellular space
plasma membrane
collagen-containing extracellular matrix
platelet alpha granule lumen
extracellular exosome
serine protease inhibitor complex
peptidase inhibitor complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
232
288
352 N-linked (GlcNAc...) asparagine
359
360
362
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
BMAL1:CLOCK,NPAS2 activates circadian gene expression Homo sapiens
Dissolution of Fibrin Clot Homo sapiens
ECM proteoglycans Homo sapiens
Platelet degranulation Homo sapiens
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Homo sapiens
Disease
Displaying entries 11 - 20 of 26 in total
DO ID Disease Name Source
DOID:14115 toxic shock syndrome
DOID:1727 retinal vein occlusion
DOID:2841 asthma
DOID:2921 glomerulonephritis
DOID:2987 familial Mediterranean fever
DOID:3082 interstitial lung disease
DOID:3393 coronary artery disease
DOID:3770 pulmonary fibrosis
DOID:4483 rhinitis
DOID:5082 liver cirrhosis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026