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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ubiquitin-like protein ISG15
Summary
- UniProt ID
- P05161
- Gene Symbol
-
- ISG15
- G1P2
- UCRP
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Antiviral defense
- Cytoplasm
- Direct protein sequencing
- Disulfide bond
- Host-virus interaction
- Innate immunity
- Isopeptide bond
- Reference proteome
- Repeat
- S-nitrosylation
- Secreted
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| cytoplasm |
| cytosol |
| nucleoplasm |
| GO Term |
|---|
| protein tag activity |
| polyubiquitin modification-dependent protein binding |
| ubiquitin protein ligase binding |
| integrin binding |
Sequence
MGWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSGVALQDRVPLASQGLGPGSTVLLVVDKCDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLRLRGGGTEPGGRS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | Homo sapiens |
| ISG15 antiviral mechanism | Homo sapiens |
| Interferon alpha/beta signaling | Homo sapiens |
| NS1 Mediated Effects on Host Pathways | Homo sapiens |
| Negative regulators of RIG-I/MDA5 signaling | Homo sapiens |
| PKR-mediated signaling | Homo sapiens |
| RSV-host interactions | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| Termination of translesion DNA synthesis | Homo sapiens |
