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Beta-2 adrenergic receptor

Summary

UniProt ID

P07550

Gene Symbol

ADRB2
ADRB2R
B2AR

Organism

Homo sapiens (human)

External Links

GlyGen: P07550
PubChem: P07550
The Human Metabolome Database: HMDBP01634
The O-GlcNAc Database: P07550

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Endosome
G-protein coupled receptor
Glycoprotein
Golgi apparatus
Hydroxylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 32 in total

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GO Term
positive regulation of transcription by RNA polymerase II
smooth muscle contraction
cell surface receptor signaling pathway
positive regulation of bone mineralization
bone resorption
negative regulation of G protein-coupled receptor signaling pathway
negative regulation of smooth muscle contraction
diet induced thermogenesis
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
activation of transmembrane receptor protein tyrosine kinase activity

Displaying entries **11 - 12** of 12 in total

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GO Term
endosome membrane
neuronal dense core vesicle

Displaying **all 8** entries
GO Term
beta2-adrenergic receptor activity
norepinephrine binding
amyloid-beta binding
adenylate cyclase binding
potassium channel regulator activity
identical protein binding
protein homodimerization activity
protein-containing complex binding

Annotation information from UniProt.

Sequence

MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	GlyTouCan ID	Source
6	N-linked (GlcNAc...) asparagine		UniProt GlyGen
15	N-linked (GlcNAc...) asparagine		UniProt GlyGen
146		G49108TO	The O-GlcNAc Database
187			GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Adrenoceptors	Homo sapiens
Cargo recognition for clathrin-mediated endocytosis	Homo sapiens
Clathrin-mediated endocytosis	Homo sapiens
G alpha (s) signalling events	Homo sapiens
Ub-specific processing proteases	Homo sapiens