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MIRAGE
open-angle glaucoma
Summary
- Synonym
-
- Wide-angle glaucoma
- glaucoma simplex
- open angle glaucoma
- pigmentary glaucoma
- Definition
- A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage.
- Super Class
- glaucoma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 154 | ADRB2 | adrenoceptor beta 2 | |
| 348 | APOE | apolipoprotein E | |
| 2762 | GMDS | GDP-mannose 4,6-dehydratase | |
| 4653 | MYOC | myocilin | |
| 5444 | PON1 | paraoxonase 1 | |
| 6890 | TAP1 | transporter 1, ATP binding cassette subfamily B member | |
| 7124 | TNF | tumor necrosis factor | |
| 10133 | OPTN | optineurin |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P01375 | Tumor necrosis factor | |
| P02649 | Apolipoprotein E | |
| P07550 | Beta-2 adrenergic receptor | |
| P27169 | Serum paraoxonase/arylesterase 1 | |
| Q03518 | Antigen peptide transporter 1 | |
| Q96CV9 | Optineurin | |
| Q99972 | Myocilin |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0007906 | Ocular hypertension |
| HP:0000593 | Abnormal anterior chamber morphology |
| HP:0012511 | Temporal optic disc pallor |
| HP:0000525 | Abnormality iris morphology |
| HP:0011003 | High myopia |
| HP:0012796 | Increased cup-to-disc ratio |
| HP:0001138 | Optic neuropathy |
| HP:0000505 | Visual impairment |
| HP:0007854 | Glaucomatous visual field defect |
| HP:0012108 | Open angle glaucoma |
