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Laminin subunit beta-1

Summary

UniProt ID

P07942

Gene Symbol

LAMB1

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011430

GlyConnect

1442

GlyGen

P07942

PubChem

P07942

The O-GlcNAc Database

P07942

O-GlcNAcAtlas

P07942

Annotation

Keyword

3D-structure
Basement membrane
Cell adhesion
Coiled coil
Disulfide bond
Glycoprotein
Laminin EGF-like domain
Lissencephaly
Phosphoprotein
Reference proteome
Repeat
Signal

Gene Ontology (GO)

Displaying entries **11 - 13** of 13 in total

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GO Term
positive regulation of integrin-mediated signaling pathway
neuronal-glial interaction involved in cerebral cortex radial glia guided migration
substrate adhesion-dependent cell spreading

Displaying entries **1 - 10** of 12 in total

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GO Term
extracellular region
basement membrane
extracellular space
laminin-1 complex
laminin-2 complex
endoplasmic reticulum lumen
perinuclear region of cytoplasm
collagen-containing extracellular matrix
extracellular exosome
protein complex involved in cell-matrix adhesion

Displaying **all 2** entries
GO Term
extracellular matrix structural constituent
structural molecule activity

Annotation information from UniProt.

Sequence

MGLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFFIDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPGSRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 19 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
120	N-linked (GlcNAc...) asparagine			UniProt GlyGen
330			G38663NM	GlyGen GlyConnect
356	N-linked (GlcNAc...) asparagine		G88520YF	UniProt GlyGen
519	N-linked (GlcNAc...) asparagine			UniProt GlyGen
677	N-linked (GlcNAc...) asparagine		G33791AF G93718GY G57776ZS G86880BF G79666IR G81263BG G92135MA G45395BF G43223CG G40574BA G08918WF G70441OD G87661QW G80223IX G25418HZ G25451PN G27058EU G84452RH G83460ZZ G41071NU G59626AS G08290VR G70101JE G80920RR G90659AW G62765YT G64527OM G05049YU G05724UK G31852PQ G23719VF G11314AS G39188ZX G41247ZX G36379GD G02815KT G06110VR	UniProt GlyGen GlyConnect
1041	N-linked (GlcNAc...) asparagine		G77669RF G79666IR G43669FQ G45395BF G20706XG G70441OD G15664MX G46691LC G04657PL G27058EU G84452RH G29184RN G10488MI G41071NU G72747WU G70619PT G59626AS G70101JE G80920RR G01485JJ G65184UU G42124LM G02886BB G23863VK G90659AW G62765YT G64527OM G72790NZ G10486CT G05049YU G28541PG G18647XP G31852PQ G72787SB G23719VF G39446WN G11314AS G41247ZX G57776ZU G02815KT G57317CE G92050GC G88520YF	GlycoProtDB UniProt GlyGen GlyConnect
1195	N-linked (GlcNAc...) asparagine			UniProt GlyGen
1279	N-linked (GlcNAc...) asparagine	16335952 19159218	G53075ES G81637OR G50856PC G82443XX G95046LV G01160VV G39471UU G05962QB G64394MX G45526EA G70232NH G55132BD G57888GL G35541EV G34617SM G93718GY G13131HA G49755GI G20312EM G80075MS G57776ZS G16125XL G52131KU G29545VG G68490OW G60834IK G86880BF G28622IK G90382BL G30970QQ G80479JV G90093AU G85282JO G20528HD G87123QX G96577RX G79666IR G81263BG G92135MA G98611JV G40834TG G45395BF G07246CJ G85554PZ G10819WX G14972EH G02030ZB G43223CG G58954YZ G37412TK G40574BA G78787DI G08918WF G48414YA G27915IV G70441OD G72797UR G87661QW G66760KM G83646BJ G76295SF G46691LC G27126ED G04657PL G25451PN G27058EU G24528MX G51640FO G70223PD G41071NU G07755XJ G86182NS G70619PT G59626AS G70101JE G80920RR G01485JJ G73968GN G42124LM G90659AW G14260UH G83633GK G62765YT G64527OM G62894KT G95177YH G05049YU G85269DF G05724UK G31852PQ G23719VF G39446WN G39188ZX G41247ZX G36379GD G02815KT G06110VR G57317CE G92050GC G92275SC G89045VA	GlycoProtDB UniProt GlyGen GlyConnect
1280			G49108TO	GlyGen The O-GlcNAc Database
1336	N-linked (GlcNAc...) asparagine		G26436YP G11101UV G81263BG G22310AV G75983OB G84452RH G62765YT G31852PQ G41247ZX	UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Degradation of the extracellular matrix	Homo sapiens
ECM proteoglycans	Homo sapiens
EGR2 and SOX10-mediated initiation of Schwann cell myelination	Homo sapiens
L1CAM interactions	Homo sapiens
Laminin interactions	Homo sapiens
MET activates PTK2 signaling	Homo sapiens
Non-integrin membrane-ECM interactions	Homo sapiens
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens

Human Protein Atlas

ENSG00000091136

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements