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Zinc finger protein GLI1

Summary

UniProt ID

P08151

Gene Symbol

GLI1
GLI

Organism

Homo sapiens (human)

External Links

GlyGen: P08151
PubChem: P08151

Annotation

Keyword

3D-structure
Acetylation
Activator
Alternative splicing
Cytoplasm
DNA-binding
Developmental protein
Differentiation
Disease variant
Isopeptide bond
Nucleus
Phosphoprotein
Proto-oncogene
Reference proteome
Repeat
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 29 in total

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GO Term
osteoblast differentiation
regulation of transcription by RNA polymerase II
regulation of DNA-templated transcription
regulation of smoothened signaling pathway
dorsal/ventral pattern formation
positive regulation of smoothened signaling pathway
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
spermatid development
positive regulation of cell population proliferation

Displaying **all 8** entries
GO Term
axoneme
ciliary tip
nucleoplasm
cytosol
nucleus
cytoplasm
ciliary base
GLI-SUFU complex

Displaying **all 10** entries
GO Term
chromatin binding
metal ion binding
transcription cis-regulatory region binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
microtubule binding
sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MFNSMTPPPISSYGEPCCLRPLPSQGAPSVGTEGLSGPPFCHQANLMSGPHSYGPARETNSCTEGPLFSSPRSAVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSPGGSYGHLSIGTMSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQELLWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPSPCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPPPEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNMSVLLRSLPGETEFLNSSA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
604				GlyGen
966				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Degradation of GLI1 by the proteasome	Homo sapiens
GLI proteins bind promoters of Hh responsive genes to promote transcription	Homo sapiens
Hedgehog 'off' state	Homo sapiens
Hedgehog 'on' state	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements