Hedgehog 'off' state

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
SMO dimerSMO dimerSUFUGLI:SUFUGLI1,2,3microtubuleKIF7:microtubuleKIF7GLI:SUFUGLI:SUFUTULP3IFT-A complex:TULP3IFT-A complexGPR161:IFT-A:TULP3GPR161ATPPPicAMPPKA tetramerPKA catalytic subunitPKA regulatory subunits:cAMPGLI3RGLI3RPTCH1 genePTCH1 gene:GLI3RPTCH1GLI1 geneGLI1 gene:GLI3RGLI1GLI2 geneGLI2 gene:GLI3RGLI2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024