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Complement factor H

Summary

UniProt ID

P08603

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011447

GlyConnect

GlyGen

P08603

PubChem

P08603

RaftProt

P08603

O-GlcNAcAtlas

P08603

Annotation

Keyword

3D-structure
Age-related macular degeneration
Alternative splicing
Complement alternate pathway
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Hemolytic uremic syndrome
Host-virus interaction
Reference proteome
Repeat
Secreted
Signal
Sulfation
Sushi

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
complement activation
regulation of complement activation
complement activation, alternative pathway
regulation of complement-dependent cytotoxicity
proteolysis
regulation of complement activation, alternative pathway

Displaying **all 6** entries
GO Term
extracellular region
extracellular space
extracellular exosome
blood microparticle
symbiont cell surface
serine-type endopeptidase complex

Displaying **all 4** entries
GO Term
complement component C3b binding
heparin binding
identical protein binding
heparan sulfate proteoglycan binding

Annotation information from UniProt.

Sequence

MRLLAKIICLMLWAICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
217	N-linked (GlcNAc...) (complex) asparagine	19139490	G43089EG G06247RL G37881RL G52527GH G45395BF G88374WZ G40574BA G08918WF G47737VJ G00912UN G48414YA G27058EU G59626AS	GlycoProtDB UniProt GlyGen GlyConnect
529	N-linked (GlcNAc...) asparagine	16335952 17591618 19159218 2963625	G06247RL G88374WZ G75983OB G00912UN G48414YA G72797UR G78644BR G20425TQ G36131WL G23863VK G31118FR G22140GZ G50045TK	UniProt GlyGen GlyConnect
718	N-linked (GlcNAc...) asparagine	17591618	G06247RL G72797UR G78644BR G20425TQ G36131WL G23863VK G31118FR G22140GZ G50045TK	UniProt GlyGen GlyConnect
775			G49108TO	GlyGen
802	N-linked (GlcNAc...) asparagine	17591618 19159218	G08146BT G42358LZ G75221WP G04909DG G57818FI G37399XV G82463GQ G22140GZ	GlycoProtDB UniProt GlyGen GlyConnect
822	N-linked (GlcNAc...) asparagine	17591618	G51941GC G06247RL G47518TP G93860XO G08146BT G22310AV G88374WZ G00912UN G42358LZ G48414YA G75221WP G85740DB G04909DG	GlycoProtDB UniProt GlyGen GlyConnect
882	N-linked (GlcNAc...) (complex) asparagine	14760718 17591618 19139490 19159218 19838169	G89205CJ G15169WU G51941GC G94917XT G06247RL G47518TP G93860XO G11629QQ G85144OK G27947YN G52527GH G04854VP G81263BG G43669FQ G07799LX G08146BT G22310AV G45395BF G88374WZ G66163OV G40926MX G59536GA G14972EH G43223CG G26330YA G05933EN G08918WF G47737VJ G71146HJ G75983OB G00875VP G00912UN G42358LZ G48414YA G92551JA G72797UR G78644BR G25418HZ G27126ED G08293MJ G75221WP G84452RH G20425TQ G36131WL G60923RB G04909DG G06356OH G37868ZX G59626AS G23863VK G31118FR G31916IQ G62765YT G10486CT G22140GZ G50045TK G72291OX G95865ZB	GlycoProtDB UniProt GlyGen GlyConnect
911	N-linked (GlcNAc...) (complex) asparagine	16335952 17591618 19139490 19159218	G12341GU G15169WU G51941GC G70232NH G94917XT G70888PK G06247RL G47518TP G93860XO G80075MS G11629QQ G57776ZS G85144OK G44753VC G43005HM G99668VU G86880BF G27947YN G52527GH G80479JV G24084IV G04854VP G94470IW G87123QX G79666IR G81263BG G43669FQ G07799LX G08146BT G45395BF G88374WZ G07246CJ G10819WX G66163OV G40926MX G59536GA G31986NC G26330YA G10846ZT G40574BA G82830MN G08918WF G47737VJ G75983OB G00912UN G42358LZ G48414YA G89098OM G11911BT G70441OD G72797UR G78644BR G46691LC G80223IX G27126ED G04657PL G08293MJ G27058EU G84452RH G46524LG G20425TQ G36131WL G41071NU G49018RC G46902YN G72747WU G60923RB G70619PT G04909DG G06356OH G59626AS G80920RR G42124LM G02886BB G23863VK G31118FR G90659AW G77547TA G45504EY G83633GK G62765YT G10486CT G22140GZ G50045TK G85269DF G95865ZB G31852PQ G57776ZU G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
1029	N-linked (GlcNAc...) (complex) asparagine	17591618 19139490 19159218	G51941GC G06247RL G93860XO G99668VU G27947YN G04854VP G94470IW G79666IR G98611JV G43669FQ G08146BT G22310AV G45395BF G88374WZ G07246CJ G40926MX G43223CG G26330YA G40574BA G82830MN G08918WF G47737VJ G75983OB G00875VP G00912UN G42358LZ G48414YA G70441OD G46691LC G27126ED G04657PL G08293MJ G27058EU G84452RH G83460ZZ G41071NU G72747WU G70619PT G04909DG G06356OH G37868ZX G59626AS G80920RR G42124LM G23863VK G31118FR G90659AW G45504EY G62765YT G95177YH G10486CT G22140GZ G50045TK G05049YU G28541PG G85269DF G95865ZB G31852PQ G41247ZX G57776ZU G02815KT G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
1095	N-linked (GlcNAc...) asparagine	17591618	G12341GU G70232NH G14547CB G70888PK G06247RL G93860XO G80075MS G77669RF G86880BF G27947YN G52527GH G90382BL G20528HD G63980BQ G04854VP G94470IW G34989PA G40834TG G08146BT G45395BF G59324HL G10819WX G40926MX G14972EH G43223CG G49642SA G58954YZ G37412TK G31986NC G26330YA G10846ZT G40574BA G82830MN G78787DI G00273SJ G08918WF G75983OB G00912UN G42358LZ G48414YA G49906RN G58087IP G92551JA G72797UR G78644BR G83646BJ G46691LC G27126ED G04657PL G27058EU G75221WP G84452RH G70223PD G20425TQ G36131WL G41071NU G07755XJ G86182NS G49018RC G46902YN G72747WU G44215PV G70619PT G04909DG G06356OH G59626AS G08290VR G02886BB G23863VK G31118FR G90659AW G45504EY G10486CT G22140GZ G50045TK G05049YU G85269DF G95865ZB G57317CE G28681TP G54010QB G84225JN	GlycoProtDB UniProt GlyGen GlyConnect