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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
E3 SUMO-protein ligase EGR2
Summary
- UniProt ID
- P11161
- Gene Symbol
-
- EGR2
- KROX20
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Activator
- Alternative splicing
- Charcot-Marie-Tooth disease
- DNA-binding
- Dejerine-Sottas syndrome
- Disease variant
- Neurodegeneration
- Nucleus
- Reference proteome
- Repeat
- Transcription regulation
- Transferase
- Ubl conjugation
- Ubl conjugation pathway
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| chromatin |
| nucleus |
| cytoplasm |
| intracellular membrane-bounded organelle |
| GO Term |
|---|
| sequence-specific DNA binding |
| sequence-specific double-stranded DNA binding |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding |
Sequence
MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 289 |
|
|||
| 299 |
|
|||
| 382 |
|
|||
| 387 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | Homo sapiens |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | Homo sapiens |
| NGF-stimulated transcription | Homo sapiens |
| Transcriptional regulation of white adipocyte differentiation | Homo sapiens |
