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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Interferon alpha/beta receptor 1
Summary
- UniProt ID
- P17181
- Gene Symbol
-
- IFNAR1
- IFNAR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Isopeptide bond
- Lysosome
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| late endosome |
| lysosome |
| plasma membrane |
| GO Term |
|---|
| JAK pathway signal transduction adaptor activity |
| type I interferon binding |
| cytokine binding |
| type I interferon receptor activity |
Sequence
MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 50 | N-linked (GlcNAc...) asparagine |
|
||
| 58 | N-linked (GlcNAc...) asparagine | |||
| 81 | N-linked (GlcNAc...) asparagine | |||
| 88 | N-linked (GlcNAc...) asparagine | |||
| 110 | N-linked (GlcNAc...) asparagine |
|
||
| 172 | N-linked (GlcNAc...) asparagine | |||
| 254 | N-linked (GlcNAc...) asparagine | |||
| 313 | N-linked (GlcNAc...) asparagine | |||
| 314 | N-linked (GlcNAc...) asparagine |
|
||
| 376 | N-linked (GlcNAc...) asparagine |
|
G75983OB
G93656SY
G04657PL
G41071NU
G33791AF
G80920RR
G22310AV
G13694XX
G81263BG
G25079LO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Evasion by RSV of host interferon responses | Homo sapiens |
| Interferon alpha/beta signaling | Homo sapiens |
| Potential therapeutics for SARS | Homo sapiens |
| Regulation of IFNA/IFNB signaling | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
