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MIRAGE
Transforming growth factor beta-1 proprotein

Summary
UniProt ID
P17246
Gene Symbol
  • Tgfb1
Gene ID
59086
Organism
Rattus norvegicus (Norway rat)
PubChem
P17246
Re-Glyco
P17246
Annotation
Keyword
  • Cleavage on pair of basic residues
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Growth factor
  • Mitogen
  • Reference proteome
  • Signal
Gene Ontology (GO)
Displaying entries 1 - 10 of 11 in total
GO Term
neuronal cell body
extracellular space
nucleus
cytoplasm
secretory granule
axon
extracellular matrix
microvillus
collagen-containing extracellular matrix
cell surface
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MPPSGLRLLPLLLPLPWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAIYDKTKDITHSIYMFFNTSDIREAVPEPPLLSRAELRLQRFKSTVEQHVELYQKYSNNSWRYLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNVLHVEINGISPKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
82 N-linked (GlcNAc...) asparagine
136 N-linked (GlcNAc...) asparagine
176 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entry 11 - 11 of 11 in total
Pathway Name Organism
TGFBR3 regulates TGF-beta signaling Rattus norvegicus
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:10763 hypertension
DOID:1168 familial hyperlipidemia
DOID:3083 chronic obstructive pulmonary disease
DOID:3770 pulmonary fibrosis
DOID:576 proteinuria
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025