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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Syndecan-1
Summary
- UniProt ID
- P18827
- Gene Symbol
-
- SDC1
- SDC
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P18827
- PubChem
- P18827
- The Human Metabolome Database
- HMDBP02143
- The O-GlcNAc Database
- P18827
- O-GlcNAcAtlas
- P18827
Annotation
- Keyword
-
- 3D-structure
- Heparan sulfate
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| response to cAMP |
| canonical Wnt signaling pathway |
| receptor-mediated endocytosis |
| response to hydrogen peroxide |
| GO Term |
|---|
| extracellular exosome |
| Golgi lumen |
| external side of plasma membrane |
| cell surface |
| lysosomal lumen |
| plasma membrane |
| protein-containing complex |
| GO Term |
|---|
| cargo receptor activity |
| identical protein binding |
Sequence
MRRAALWLWLCALALSLQPALPQIVATNLPPEDQDGSGDDSDNFSGSGAGALQDITLSQQTPSTWKDTQLLTAIPTSPEPTGLEATAASTSTLPAGEGPKEGEAVVLPEVEPGLTAREQEATPRPRETTQLPTTHLASTTTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 156 |
|
|||
| 164 |
|
|||
| 165 |
|
|||
| 166 |
|
|||
| 171 |
|
|||
| 177 |
|
|||
| 180 |
|
|||
| 186 |
|
|||
| 188 |
|
|||
| 197 |
|
G57321FI
G73004SD
G58001LT
G43417UB
G29068FM
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Homo sapiens |
| Attachment and Entry | Homo sapiens |
| Cell surface interactions at the vascular wall | Homo sapiens |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | Homo sapiens |
| Defective B3GAT3 causes JDSSDHD | Homo sapiens |
| Defective B4GALT7 causes EDS, progeroid type | Homo sapiens |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | Homo sapiens |
| Defective EXT2 causes exostoses 2 | Homo sapiens |
| HS-GAG biosynthesis | Homo sapiens |
| HS-GAG degradation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:399 | tuberculosis | |
| DOID:4001 | ovarian carcinoma | |
| DOID:4006 | bladder urothelial carcinoma | |
| DOID:4007 | bladder carcinoma | |
| DOID:4015 | sarcomatoid carcinoma | |
| DOID:4074 | pancreatic adenocarcinoma | |
| DOID:409 | liver disease | |
| DOID:4159 | skin cancer | |
| DOID:417 | autoimmune disease | |
| DOID:418 | systemic scleroderma |
