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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
Interleukin-10
Summary
- UniProt ID
- P22301
- Gene Symbol
-
- IL10
- Gene ID
- 3586
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytokine
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| GO Term |
|---|
| protein dimerization activity |
| interleukin-10 receptor binding |
| cytokine activity |
| growth factor activity |
Sequence
MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 134 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CD163 mediating an anti-inflammatory response | Homo sapiens |
| FCGR3A-mediated IL10 synthesis | Homo sapiens |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Signaling by ALK fusions and activated point mutants | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:684 | hepatocellular carcinoma | |
| DOID:686 | liver carcinoma | |
| DOID:7148 | rheumatoid arthritis | |
| DOID:8483 | retinal artery occlusion | |
| DOID:8552 | chronic myeloid leukemia | |
| DOID:8778 | Crohn's disease | |
| DOID:8893 | psoriasis | |
| DOID:8924 | autoimmune thrombocytopenic purpura | |
| DOID:8947 | diabetic retinopathy | |
| DOID:9074 | systemic lupus erythematosus |
