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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

P26450

Gene Symbol

Pik3r1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P26450
PubChem: P26450
O-GlcNAcAtlas: P26450

Annotation

Keyword

Acetylation
Direct protein sequencing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
response to insulin
cellular response to insulin stimulus
positive regulation of protein import into nucleus
phosphatidylinositol 3-kinase/protein kinase B signal transduction
phosphatidylinositol metabolic process
phosphatidylinositol phosphate biosynthetic process
insulin-like growth factor receptor signaling pathway
response to glucocorticoid
positive regulation of synapse assembly
regulation of protein localization to plasma membrane

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GO Term
perinuclear endoplasmic reticulum membrane

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GO Term
calmodulin binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
nuclear estrogen receptor binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
insulin receptor substrate binding
protein heterodimerization activity
ATPase binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
541			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Mus musculus
CD28 dependent PI3K/Akt signaling	Mus musculus
CDC42 GTPase cycle	Mus musculus
Costimulation by the CD28 family	Mus musculus
DAP12 signaling	Mus musculus
Downstream TCR signaling	Mus musculus
Downstream signal transduction	Mus musculus
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Mus musculus
Extra-nuclear estrogen signaling	Mus musculus
FLT3 Signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements