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MIRAGE
Tyrosine-protein phosphatase non-receptor type 11
Summary
- UniProt ID
- P35235
- Gene Symbol
-
- Ptpn11
- Gene ID
- 19247
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Repeat
- SH2 domain
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| protein-containing complex |
| cytosol |
| GO Term |
|---|
| peptide hormone receptor binding |
Sequence
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR
Glycosylation Sites
G41840AI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| RET signaling | Mus musculus |
| Regulation of IFNA/IFNB signaling | Mus musculus |
| Regulation of RUNX1 Expression and Activity | Mus musculus |
| Signaling by CSF3 (G-CSF) | Mus musculus |
| Signaling by SCF-KIT | Mus musculus |
| Spry regulation of FGF signaling | Mus musculus |
| Tie2 Signaling | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:0050868 | hepatocellular adenoma | |
| DOID:0060250 | idiopathic scoliosis | |
| DOID:0060578 | Noonan syndrome 1 | |
| DOID:11984 | hypertrophic cardiomyopathy | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:14291 | Noonan syndrome with multiple lentigines |
