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Signal transducer and activator of transcription 3

Summary

UniProt ID

P42227

Gene Symbol

Aprf
Stat3

Gene ID

20848

Organism

Mus musculus (house mouse)

External Links

GlyGen: P42227
PubChem: P42227
The O-GlcNAc Database: P42227
RaftProt: P42227
O-GlcNAcAtlas: P42227
Re-Glyco: P42227

Annotation

Keyword

3D-structure
Acetylation
Activator
Acute phase
Alternative splicing
Cytoplasm
DNA-binding
Direct protein sequencing
Nucleus
Phosphoprotein
Reference proteome
SH2 domain
Transcription regulation

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
nucleus
protein-containing complex
nucleoplasm
cytosol
transcription regulator complex
chromatin
cytoplasm
plasma membrane
RNA polymerase II transcription regulator complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 65 in total

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GO Term
regulation of feeding behavior
cell population proliferation
negative regulation of cell population proliferation
positive regulation of gene expression
phosphorylation
cytokine-mediated signaling pathway
sexual reproduction
positive regulation of cell migration
glucose homeostasis
eating behavior

Displaying entries **11 - 20** of 22 in total

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GO Term
signaling adaptor activity
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
protein dimerization activity
RNA polymerase II-specific DNA-binding transcription factor binding
primary miRNA binding
DNA-binding transcription factor binding
transcription cis-regulatory region binding
nuclear receptor activity

Annotation information from UniProt.

Sequence

MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	GlyTouCan ID	Source
401	G97993TU	GlyGen
714	G49108TO	GlyGen The O-GlcNAc Database
716	G49108TO	GlyGen
717	G49108TO	GlyGen The O-GlcNAc Database
719	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Downstream signal transduction	Mus musculus
Interleukin-10 signaling	Mus musculus
Interleukin-15 signaling	Mus musculus
Interleukin-20 family signaling	Mus musculus
Interleukin-21 signaling	Mus musculus
Interleukin-23 signaling	Mus musculus
Interleukin-27 signaling	Mus musculus
Interleukin-35 Signalling	Mus musculus
Interleukin-37 signaling	Mus musculus
Interleukin-4 and Interleukin-13 signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements