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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Lanosterol synthase
Summary
- UniProt ID
- P48449
- Gene Symbol
-
- LSS
- OSC
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P48449
- PubChem
- P48449
- SwissLipids
- The Human Metabolome Database
- HMDBP00430
- The O-GlcNAc Database
- P48449
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cataract
- Direct protein sequencing
- Disease variant
- Endoplasmic reticulum
- Hypotrichosis
- Intellectual disability
- Isomerase
- Membrane
- Reference proteome
- Repeat
- Steroid biosynthesis
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum membrane |
| lipid droplet |
| membrane |
| GO Term |
|---|
| lanosterol synthase activity |
Sequence
MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of gene expression by SREBF (SREBP) | Homo sapiens |
| Cholesterol biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4766 | embryoma | |
| DOID:5076 | mixed glioma | |
| DOID:526 | human immunodeficiency virus infectious disease | |
| DOID:5604 | adult acute lymphocytic leukemia | |
| DOID:5744 | ovary serous adenocarcinoma | |
| DOID:5750 | endometrial serous adenocarcinoma | |
| DOID:6193 | epithelioid sarcoma | |
| DOID:635 | acquired immunodeficiency syndrome | |
| DOID:6652 | diffuse idiopathic skeletal hyperostosis | |
| DOID:6725 | spinal stenosis |
