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Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

Summary

UniProt ID

P62715

Gene Symbol

Ppp2cb

Organism

Mus musculus (house mouse)

External Links

GlyGen: P62715
The O-GlcNAc Database: P62715
RaftProt: P62715

Annotation

Keyword

Centromere
Chromosome
Cytoskeleton
Direct protein sequencing
Manganese
Metal-binding
Methylation
Nucleus
Phosphoprotein
Protein phosphatase
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
mitotic cell cycle
regulation of gene expression
negative regulation of gene expression
proteasome-mediated ubiquitin-dependent protein catabolic process
response to antibiotic
negative regulation of Ras protein signal transduction
apoptotic mitochondrial changes
response to lead ion
negative regulation of tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress

Displaying **all 6** entries
GO Term
nucleus
cytoplasm
cytosol
protein phosphatase type 2A complex
chromosome, centromeric region
spindle pole

Displaying **all 5** entries
GO Term
metal ion binding
myosin phosphatase activity
transmembrane transporter binding
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity

Annotation information from UniProt.

Sequence

MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 23 in total

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Pathway Name	Organism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	Mus musculus
Beta-catenin phosphorylation cascade	Mus musculus
CTLA4 inhibitory signaling	Mus musculus
Cyclin A/B1/B2 associated events during G2/M transition	Mus musculus
Cyclin D associated events in G1	Mus musculus
DARPP-32 events	Mus musculus
Degradation of beta-catenin by the destruction complex	Mus musculus
Disassembly of the destruction complex and recruitment of AXIN to the membrane	Mus musculus
EML4 and NUDC in mitotic spindle formation	Mus musculus
ERK/MAPK targets	Mus musculus