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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
TGF-beta receptor type-2
Summary
- UniProt ID
- Q62312
- Gene Symbol
-
- Tgfbr2
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0005592
- PubChem
- Q62312
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Apoptosis
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth regulation
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| caveola |
| external side of plasma membrane |
| cell surface |
| plasma membrane |
| receptor complex |
| membrane raft |
| transforming growth factor beta ligand-receptor complex |
| GO Term |
|---|
| kinase activator activity |
| mitogen-activated protein kinase kinase kinase binding |
Sequence
MGRGLLRGLWPLHIVLWTRIASTIPPHVPKSVNSDVMASDNGGAVKLPQLCKFCDVRLSTCDNQKSCMSNCSITAICEKPHEVCVAVWRKNDKNITLETVCHDPKLTYHGFTLEDAASPKCVMKEKKRAGETFFMCACNMEECNDYIIFSEEYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLSPSWESSKPRKLMDFSDNCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYSSWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWDHDPEARLTAQCVAERFSELEHPERLSGRSCSQEKIPEDGSLNTTK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 48 |
|
|
||
| 70 | N-linked (GlcNAc...) asparagine |
|
||
| 94 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downregulation of TGF-beta receptor signaling | Mus musculus |
| TGF-beta receptor signaling activates SMADs | Mus musculus |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Mus musculus |
| TGFBR3 regulates TGF-beta signaling | Mus musculus |
