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Interleukin-27 receptor subunit alpha

Summary

UniProt ID

Q6UWB1

Gene Symbol

IL27RA
CRL1
TCCR
WSX1

Organism

Homo sapiens (human)

External Links

PubChem: Q6UWB1

Annotation

Keyword

3D-structure
Glycoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 14 in total

1

2

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GO Term
positive regulation of T-helper 1 type immune response
negative regulation of type 2 immune response
immune response
cell surface receptor signaling pathway
cytokine-mediated signaling pathway
negative regulation of interleukin-17 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of type II interferon production
negative regulation of neuron apoptotic process

Displaying **all 3** entries
GO Term
receptor complex
plasma membrane
external side of plasma membrane

Displaying **all 3** entries
GO Term
interleukin-27 receptor activity
transmembrane signaling receptor activity
cytokine binding

Annotation information from UniProt.

Sequence

MRGGRGAPFWLWPLPKLALLPLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESSQPAQATAPLDSGYEKHFLPTPEELGLLGPPRPQVLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
51	N-linked (GlcNAc...) asparagine	UniProt
76	N-linked (GlcNAc...) asparagine	UniProt
302	N-linked (GlcNAc...) asparagine	UniProt
311	N-linked (GlcNAc...) asparagine	UniProt
374	N-linked (GlcNAc...) asparagine	UniProt
382	N-linked (GlcNAc...) asparagine	UniProt
467	N-linked (GlcNAc...) asparagine	UniProt