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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Extracellular sulfatase Sulf-1
Summary
- UniProt ID
- Q8IWU6
- Gene Symbol
-
- SULF1
- KIAA1077
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- Q8IWU6
- The Human Metabolome Database
- HMDBP02295
- RaftProt
- Q8IWU6
Annotation
- Keyword
-
- Apoptosis
- Calcium
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Hydrolase
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| Golgi apparatus |
| plasma membrane |
| membrane raft |
| endoplasmic reticulum |
| Golgi stack |
| cell surface |
| GO Term |
|---|
| arylsulfatase activity |
| N-acetylglucosamine-6-sulfatase activity |
| calcium ion binding |
| glycosaminoglycan binding |
Sequence
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSSNAVGPPTTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIKNLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKENNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 64 | N-linked (GlcNAc...) asparagine |
|
||
| 111 | N-linked (GlcNAc...) asparagine | |||
| 131 | N-linked (GlcNAc...) asparagine | |||
| 148 | N-linked (GlcNAc...) asparagine | |||
| 170 | N-linked (GlcNAc...) asparagine | |||
| 197 | N-linked (GlcNAc...) asparagine | |||
| 240 | N-linked (GlcNAc...) asparagine | |||
| 623 | N-linked (GlcNAc...) asparagine | |||
| 773 | N-linked (GlcNAc...) asparagine |
|
||
| 783 | N-linked (GlcNAc...) asparagine |
|
G15664MX
G49018RC
G72747WU
G90659AW
G65000LJ
G62765YT
G64527OM
G05724UK
G31852PQ
G41247ZX
G00912UN
G48414YA
G06356OH
G80920RR
G72790NZ
G95865ZB
G02815KT
G01650EU
G37399XV
G28541PG
G39446WN
G57776ZS
G44753VC
G99668VU
G86880BF
G27947YN
G79666IR
G40926MX
G40574BA
G70441OD
G83646BJ
G27058EU
G83460ZZ
G59626AS
G10486CT
G06110VR
G78787DI
G46503DX
G48584BU
G70101JE
G49955PK
G39188ZX
G72667IM
G84452RH
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:684 | hepatocellular carcinoma | |
| DOID:686 | liver carcinoma | |
| DOID:8398 | osteoarthritis | |
| DOID:848 | arthritis | |
| DOID:8923 | skin melanoma | |
| DOID:8991 | cervix uteri carcinoma in situ | |
| DOID:90 | degenerative disc disease | |
| DOID:9087 | anal carcinoma in situ | |
| DOID:9256 | colorectal cancer | |
| DOID:9277 | primary cerebellar degeneration |
