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MIRAGE
E3 ubiquitin-protein ligase RNF168
Summary
- UniProt ID
- Q8IYW5
- Gene Symbol
-
- RNF168
- Gene ID
- 165918
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Chromatin regulator
- DNA repair
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transferase
- Ubl conjugation
- Ubl conjugation pathway
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| protein-containing complex |
| nucleoplasm |
| cytosol |
| ubiquitin ligase complex |
| site of double-strand break |
Sequence
MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASHSEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMPWLCACGAEWYHEGNVKTRPSNHGKELCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSGVTQTNGNNTGETENEESCLLISKEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEINFTQKLIDLEHLLFERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATSSPPDKVLNGQRKNPKDGNFKRQTHTKHPTPERGSRDKNRQVSLKMQLKQSVNRRKMPNSTRDHCKVSKSAHSLQPSISQKSVFQMFQRCTK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 358 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G2/M DNA damage checkpoint | Homo sapiens |
| Nonhomologous End-Joining (NHEJ) | Homo sapiens |
| Processing of DNA double-strand break ends | Homo sapiens |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | Homo sapiens |
| SUMOylation of DNA damage response and repair proteins | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090113 | RIDDLE syndrome |
