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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
Synaptotagmin-2
Summary
- UniProt ID
- Q8N9I0
- Gene Symbol
-
- SYT2
- Gene ID
- 127833
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q8N9I0
- PubChem
- Q8N9I0
- The Human Metabolome Database
- HMDBP08029
- The O-GlcNAc Database
- Q8N9I0
- Re-Glyco
- Q8N9I0
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Congenital myasthenic syndrome
- Cytoplasm
- Cytoplasmic vesicle
- Differentiation
- Disease variant
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Synapse
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| axon |
| dense core granule |
| synaptic vesicle membrane |
| exocytic vesicle |
| clathrin-coated endocytic vesicle membrane |
| chromaffin granule membrane |
| GO Term |
|---|
| metal ion binding |
| inositol 1,3,4,5 tetrakisphosphate binding |
| calcium ion sensor activity |
| SNARE binding |
| calcium-dependent phospholipid binding |
Sequence
MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 29 | N-linked (GlcNAc...) asparagine |
|
||
| 157 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| Neurexins and neuroligins | Homo sapiens |
| Toxicity of botulinum toxin type B (botB) | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110659 | congenital myasthenic syndrome 7 | |
| DOID:3635 | congenital myasthenic syndrome |
