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Neurexin-1

Summary
UniProt ID
Q9ULB1
Gene Symbol
  • KIAA0578
  • NRXN1
Gene ID
9378
Organism
Homo sapiens (human)
GlyConnect
GlyGen
Q9ULB1
PubChem
Q9ULB1
The O-GlcNAc Database
Q9ULB1
O-GlcNAcAtlas
Q9ULB1
Re-Glyco
Q9ULB1
Annotation
Keyword
  • 3D-structure
  • Alternative promoter usage
  • Alternative splicing
  • Calcium
  • Cell adhesion
  • Cell membrane
  • Cell projection
  • Disulfide bond
  • EGF-like domain
  • Heparan sulfate
  • Intellectual disability
  • Metal-binding
  • Reference proteome
  • Repeat
  • Schizophrenia
  • Signal
  • Synapse
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 9 entries
GO Term
cell surface
nucleolus
plasma membrane
nuclear membrane
vesicle
cell projection
neuronal cell body
endoplasmic reticulum
presynaptic membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MYQRMLRCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
125 N-linked (GlcNAc...) asparagine
190 N-linked (GlcNAc...) asparagine
790 N-linked (GlcNAc...) asparagine
1024
1223 N-linked (GlcNAc...) asparagine
1355 O-linked (Xyl...) (heparan sulfate) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Neurexins and neuroligins Homo sapiens
Non-integrin membrane-ECM interactions Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0111332 Pitt-Hopkins-like syndrome 2
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025