GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G00048MO	115
IgM	Patient 3	4	mild	G00048MO	113
IgA	Patient 4	12	mild	G00048MO	422
IgG	Patient 4	12	mild	G00048MO	119
IgM	Patient 4	12	mild	G00048MO	340
IgA	Patient 1	10	moderate	G00051MO	367
IgA	Patient 1	22	moderate	G00051MO	292
IgA	Patient 1	6	moderate	G00051MO	355
IgG	Patient 1	10	moderate	G00051MO	22
IgG	Patient 1	22	moderate	G00051MO	22
IgG	Patient 1	6	moderate	G00051MO	23
IgM	Patient 1	10	moderate	G00051MO	37
IgM	Patient 1	22	moderate	G00051MO	30
IgM	Patient 1	6	moderate	G00051MO	27
IgA	Patient 2	15	mild	G00051MO	235
IgA	Patient 2	24	mild	G00051MO	271
IgG	Patient 2	15	mild	G00051MO	27
IgG	Patient 2	24	mild	G00051MO	24
IgM	Patient 2	15	mild	G00051MO	41
IgM	Patient 2	24	mild	G00051MO	40
IgA	Patient 2	3	mild	G00051MO	251
IgG	Patient 2	3	mild	G00051MO	27
IgM	Patient 2	3	mild	G00051MO	48
IgA	Patient 3	-180	mild	G00051MO	251
IgA	Patient 3	11	mild	G00051MO	428