• G10639

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:a-lgal-HEX-1:5|6:d
4b:b-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(4+1)4d

• Wang G et al. Molecular genetic basis for the variable expression of Lewis Y antigen in Helicobacter pylori: analysis of the alpha (1,2) fucosyltransferase gene. Mol Microbiol. 1999 Feb;31:(4):1265-74. doi: 10.1046/j.1365-2958.1999.01268.x. PMID: 10096092.

• Knirel YA et al. Structural studies on lipopolysaccharides of serologically non-typable strains of Helicobacter pylori, AF1 and 007, expressing Lewis antigenic determinants. Eur J Biochem. 1999 Nov;266:(1):123-31. doi: 10.1046/j.1432-1327.1999.00831.x. PMID: 10542057.

• Logan SM et al. Functional genomics of Helicobacter pylori: identification of a beta-1,4 galactosyltransferase and generation of mutants with altered lipopolysaccharide. Mol Microbiol. 2000 Mar;35:(5):1156-67. doi: 10.1046/j.1365-2958.2000.01784.x. PMID: 10712696.

• Appelmelk BJ et al. Phase variation in H type I and Lewis a epitopes of Helicobacter pylori lipopolysaccharide. Infect Immun. 2000 Oct;68:(10):5928-32. doi: 10.1128/iai.68.10.5928-5932.2000. PMID: 10992504.

• Altman E et al. Characterization of murine monoclonal antibodies against Helicobacter pylori lipopolysaccharide specific for Lex and Ley blood group determinants. Biochem Cell Biol. 2005 Oct;83:(5):589-96. doi: 10.1139/o05-052. PMID: 16234847.

• Chan NW et al. The biosynthesis of Lewis X in Helicobacter pylori. Glycobiology. 1995 Oct;5:(7):683-8. doi: 10.1093/glycob/5.7.683. PMID: 8608270.

• Martin SL et al. Lewis X biosynthesis in Helicobacter pylori. Molecular cloning of an alpha(1,3)-fucosyltransferase gene. J Biol Chem. 1997 Aug 22;272:(34):21349-56. doi: 10.1074/jbc.272.34.21349. PMID: 9261148.

• Monteiro MA et al. Simultaneous expression of type 1 and type 2 Lewis blood group antigens by Helicobacter pylori lipopolysaccharides. Molecular mimicry between h. pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms. J Biol Chem. 1998 May 8;273:(19):11533-43. doi: 10.1074/jbc.273.19.11533. PMID: 9565568.

• Nakayama F et al. CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV. J Biol Chem. 2001 May 11;276:(19):16100-6. doi: 10.1074/jbc.M007272200. PMID: 11278338.

• Saarinen J et al. N-glycan structures of matrix metalloproteinase-1 derived from human fibroblasts and from HT-1080 fibrosarcoma cells. Eur J Biochem. 1999 Feb;259:(3):829-40. doi: 10.1046/j.1432-1327.1999.00105.x. PMID: 10092871.

• Izawa M et al. Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer. Cancer Res. 2000 Mar 1;60:(5):1410-6. PMID: 10728707.

• Sittel C et al. Ki-67 (MIB1), p53, and Lewis-X (LeuM1) as prognostic factors of recurrence in T1 and T2 laryngeal carcinoma. Laryngoscope. 2000 Jun;110:(6):1012-7. doi: 10.1097/00005537-200006000-00024. PMID: 10852523.

• Benharroch D et al. Differential expression of sialyl and non-sialyl-CD15 antigens on Hodgkin-Reed-Sternberg cells: significance in Hodgkin's disease. Leuk Lymphoma. 2000 Sep;39:(1-2):185-94. doi: 10.3109/10428190009053553. PMID: 10975398.

• Muroi K et al. Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells. Blood. 1992 Feb 1;79:(3):713-9. PMID: 1370643.

• Nakayama J et al. Immunohistochemical demonstration of glycoconjugates bearing the type 2 chain-backbone structure in human fetal, normal and neoplastic gastrointestinal tract. Histochemistry. 1992 May;97:(4):303-10. doi: 10.1007/BF00270030. PMID: 1618643.

• Naarding MA et al. Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes. J Clin Invest. 2005 Nov;115:(11):3256-64. doi: 10.1172/JCI25105. PMID: 16239964.

• Ohtani H et al. Qualitative difference of subcellular localization of tumor-associated carbohydrate (Le(x)) antigens in renal cell carcinoma and normal kidney. J Histochem Cytochem. 1991 Apr;39:(4):479-84. doi: 10.1177/39.4.1672317. PMID: 1672317.

• Hirabayashi Y et al. Characterization of a novel Le(x)-active ganglioside from chick intestinal tissues recognized by murine monoclonal antibody 188C1. J Biol Chem. 1991 Jun 5;266:(16):10268-74. PMID: 1674743.

• Yoshinaga K et al. Immunohistochemical localization of the carbohydrate antigen 4C9 in the mouse embryo: a reliable marker of mouse primordial germ cells. Differentiation. 1991 Nov;48:(2):75-82. doi: 10.1111/j.1432-0436.1991.tb00245.x. PMID: 1773918.

• Muramatsu H et al. Embryonic stem cells deficient in I beta1,6-N-acetylglucosaminyltransferase exhibit reduced expression of embryoglycan and the loss of a Lewis X antigen, 4C9. Glycobiology. 2008 Mar;18:(3):242-9. doi: 10.1093/glycob/cwm138. PMID: 18184719.

• Stroud MR et al. Extended type 1 chain glycosphingolipids: dimeric Lea (III4V4Fuc2Lc6) as human tumor-associated antigen. J Biol Chem. 1991 May 5;266:(13):8439-46. PMID: 2022659.

• Singhal AK et al. Profiles of Lewisx-containing glycoproteins and glycolipids in sera of patients with adenocarcinoma. Cancer Res. 1990 Mar 1;50:(5):1375-80. PMID: 2302702.

• Gooi HC et al. Differences in the fine specificities of monoclonal (Class A) antibodies to human myeloid cells. Clin Exp Immunol. 1985 Apr;60:(1):151-8. PMID: 2408796.

• Okada Y et al. Human hepatocellular carcinoma-associated changes of glycosphingolipids detected by two monoclonal antibodies FH2 and IB9. J Hepatol. 1986;2:(3):430-40. doi: 10.1016/s0168-8278(86)80054-x. PMID: 2424969.

• Hakomori S et al. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv Cancer Res. 1989;52:257-331. doi: 10.1016/s0065-230x(08)60215-8. PMID: 2662714.

• Holmes EH et al. Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase. J Biol Chem. 1987 Nov 15;262:(32):15649-58. PMID: 2960671.

• Holmes EH et al. Oncofetal expression of Lex carbohydrate antigens in human colonic adenocarcinomas. Regulation through type 2 core chain synthesis rather than fucosylation. J Biol Chem. 1987 Aug 15;262:(23):11331-8. PMID: 3112156.

• Marcus DM et al. Monoclonal antibodies that bind to galactosylgloboside (SSEA-3 antigen). Arch Biochem Biophys. 1988 May 1;262:(2):620-5. doi: 10.1016/0003-9861(88)90414-6. PMID: 3364985.

• Nomoto S et al. An anti-carbohydrate monoclonal antibody inhibits cell-substratum adhesion of F9 embryonal carcinoma cells. Exp Cell Res. 1986 May;164:(1):49-62. doi: 10.1016/0014-4827(86)90453-2. PMID: 3754220.

• Kannagi R et al. Lea-active heptaglycosylceramide, a hybrid of type 1 and type 2 chain, and the pattern of glycolipids with Lea, Leb, X (Lex), and Y (Ley) determinants in human blood cell membranes (ghosts). Evidence that type 2 chain can elongate repetitively but type 1 chain cannot. J Biol Chem. 1985 May 25;260:(10):6410-5. PMID: 3997830.

• Huang LC et al. My-1, the human myeloid-specific antigen detected by mouse monoclonal antibodies, is a sugar sequence found in lacto-N-fucopentaose III. Blood. 1983 May;61:(5):1020-3. PMID: 6187397.

• Urdal DL et al. A granulocyte reactive monoclonal antibody, 1G10, identifies the Gal beta 1-4 (Fuc alpha 1-3)GlcNAc (X determinant) expressed in HL-60 cells on both glycolipid and glycoprotein molecules. Blood. 1983 Nov;62:(5):1022-6. PMID: 6194834.

• Fukushi Y et al. Novel fucolipids accumulating in human adenocarcinoma. II. Selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain. J Biol Chem. 1984 Apr 10;259:(7):4681-5. PMID: 6200484.

• Cuttitta F et al. Monoclonal antibodies that demonstrate specificity for several types of human lung cancer. Proc Natl Acad Sci U S A. 1981 Jul;78:(7):4591-5. doi: 10.1073/pnas.78.7.4591. PMID: 6270685.

• Hakomori S et al. Glycosphingolipids as tumor-associated and differentiation markers. J Natl Cancer Inst. 1983 Aug;71:(2):231-51. PMID: 6576183.

• Huang LC et al. Many monoclonal antibodies with an apparent specificity for certain lung cancers are directed against a sugar sequence found in lacto-N-fucopentaose III. Arch Biochem Biophys. 1983 Jan;220:(1):318-20. doi: 10.1016/0003-9861(83)90417-4. PMID: 6830241.

• Cooling LL et al. Detection in human blood platelets of sialyl Lewis X gangliosides, potential ligands for CD62 and other selectins. Glycobiology. 1995 Sep;5:(6):571-81. doi: 10.1093/glycob/5.6.571. PMID: 8563144.

• Warren HS et al. A carbohydrate structure associated with CD15 (Lewis x) on myeloid cells is a novel ligand for human CD2. J Immunol. 1996 Apr 15;156:(8):2866-73. PMID: 8609406.

• Karagenç L et al. Origin of primordial germ cells in the prestreak chick embryo. Dev Genet. 1996;19:(4):290-301. doi: 10.1002/(SICI)1520-6408(1996)19:4<290::AID-DVG2>3.0.CO;2-4. PMID: 9023982.

• Wagers AJ et al. Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes. J Immunol. 1997 Aug 15;159:(4):1917-29. PMID: 9257857.

• Weninger W et al. Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels. Immunity. 2000 Jun;12:(6):665-76. doi: 10.1016/s1074-7613(00)80217-4. PMID: 10894166.

• Geyer A et al. Calcium-Dependent Carbohydrate-Carbohydrate Recognition between Lewis(X) Blood Group Antigens This research was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie. Angew Chem Int Ed Engl. 2000 Sep 15;39:(18):3245-3249. doi: 10.1002/1521-3773(20000915)39:18<3245::aid-anie3245>3.0.co;2-9. PMID: 11028065.

• Kudo T et al. Normal embryonic and germ cell development in mice lacking alpha 1,3-fucosyltransferase IX (Fut9) which show disappearance of stage-specific embryonic antigen 1. Mol Cell Biol. 2004 May;24:(10):4221-8. doi: 10.1128/mcb.24.10.4221-4228.2004. PMID: 15121843.

• Azuma Y et al. Expression of cell surface Lewis X and Y antigens and FUT4 mRNA is increased in Jurkat cells undergoing apoptosis. Biochim Biophys Acta. 2004 Jun 11;1672:(3):157-63. doi: 10.1016/j.bbagen.2004.03.006. PMID: 15182935.

• Lenkei R et al. Expression of CD15 as predictor of relapse in children with acute lymphoblastic leukemia of the pre-B type. Leuk Res. 1991;15:(4):189-94. doi: 10.1016/0145-2126(91)90120-i. PMID: 1674292.

• Eggens I et al. Specific interaction between Lex and Lex determinants. A possible basis for cell recognition in preimplantation embryos and in embryonal carcinoma cells. J Biol Chem. 1989 Jun 5;264:(16):9476-84. PMID: 2470757.

• Hakomori S et al. The hapten structure of a developmentally regulated glycolipid antigen (SSEA-1) isolated from human erythrocytes and adenocarcinoma: a preliminary note. Biochem Biophys Res Commun. 1981 Jun;100:(4):1578-86. doi: 10.1016/0006-291x(81)90699-9. PMID: 6117281.

• Gooi HC et al. Stage-specific embryonic antigen involves alpha 1 goes to 3 fucosylated type 2 blood group chains. Nature. 1981 Jul 9;292:(5819):156-8. doi: 10.1038/292156a0. PMID: 6165896.