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Repository for lectin-assisted multimodality data
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MIRAGE
CD209 antigen
Summary
- Lectin Name Aliases
-
- DC-SIGN
- LSECtin CRD Fc
- Monosaccharide Specificities
-
- Man
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Calcium
- Cell adhesion
- Cell membrane
- Disulfide bond
- Endocytosis
- Glycoprotein
- Host cell receptor for virus entry
- Host-virus interaction
- Innate immunity
- Mannose-binding
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| host cell |
| external side of plasma membrane |
| cell surface |
| extracellular region |
| cytoplasm |
| plasma membrane |
| membrane |
| GO Term |
|---|
| mannose binding |
| carbohydrate binding |
| metal ion binding |
| virus receptor activity |
| peptide antigen binding |
| virion binding |
Reference
| PubMed ID | Title | First Author |
|---|---|---|
| 16484342 | Glycosyltransferases involved in type 1 chain and Lewis antigen biosynthesis exhibit glycan and core chain specificity. | Holgersson J |
| 16682406 | Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins. | Powlesland AS |
| 17145745 | DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues. | Bogoevska V |
| 17617634 | Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan. | Doz E |
| 17913713 | Expression of bisecting type and Lewisx/Lewisy terminated N-glycans on human sperm. | Pang PC |
| 18073208 | Structural requirements for multimerization of the pathogen receptor dendritic cell-specific ICAM3-grabbing non-integrin (CD209) on the cell surface. | Serrano-Gómez D |
| 18482990 | Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. | Cambi A |
| 18633134 | Glycoconjugate microarray based on an evanescent-field fluorescence-assisted detection principle for investigation of glycan-binding proteins. | Tateno H |
| 19386588 | MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN). | Martinez-Nunez RT |
| 19502234 | DC-SIGN neck domain is a pH-sensor controlling oligomerization: SAXS and hydrodynamic studies of extracellular domain. | Tabarani G |
Pathway
| Pathway Name | Organism |
|---|---|
| Butyrophilin (BTN) family interactions | Homo sapiens |
| CD209 (DC-SIGN) signaling | Homo sapiens |
| RSV-host interactions | Homo sapiens |
UniLectin
| UniProt |
|---|
| Q9NNX6 |
CarboGrove
- Lectin Name
- DC-SIGN
- Common Name
- DC-SIGN
- Automated Analysis report (Top 10 high affinity glycans)
- Array Source
- Microbial
- Protein Source
- Investigator Provided
- Concentration (ug/mL)
-
G26425MP
G25559RS
G32046JJ
G48796BQ
G64541AU
G39023AU
G61491DK
G07682RX
G00052MO
G53402KW
G00051MO
