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Repository for lectin-assisted multimodality data
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MIRAGE
CD209 antigen
Summary
- Lectin Name Aliases
-
- DC-SIGN
- LSECtin CRD Fc
- Monosaccharide Specificities
-
- Man
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Calcium
- Cell adhesion
- Cell membrane
- Disulfide bond
- Endocytosis
- Glycoprotein
- Host cell receptor for virus entry
- Host-virus interaction
- Innate immunity
- Mannose-binding
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| host cell |
| external side of plasma membrane |
| cell surface |
| extracellular region |
| cytoplasm |
| plasma membrane |
| membrane |
| GO Term |
|---|
| mannose binding |
| carbohydrate binding |
| metal ion binding |
| virus receptor activity |
| peptide antigen binding |
| virion binding |
Reference
| PubMed ID | Title | First Author |
|---|---|---|
| 19837675 | Profiling carbohydrate-receptor interaction with recombinant innate immunity receptor-Fc fusion proteins. | Hsu TL |
| 20080962 | Functional interaction of common allergens and a C-type lectin receptor, dendritic cell-specific ICAM3-grabbing non-integrin (DC-SIGN), on human dendritic cells. | Hsu SC |
| 20507987 | Microvirin, a novel alpha(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has anti-HIV-1 activity comparable with that of cyanovirin-N but a much higher safety profile. | Huskens D |
| 21112966 | Survey of immune-related, mannose/fucose-binding C-type lectin receptors reveals widely divergent sugar-binding specificities. | Lee RT |
| 21474492 | Pichia pastoris-produced mucin-type fusion proteins with multivalent O-glycan substitution as targeting molecules for mannose-specific receptors of the immune system. | Gustafsson A |
| 21515679 | Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) recognizes a novel ligand, Mac-2-binding protein, characteristically expressed on human colorectal carcinomas. | Nonaka M |
| 21646346 | MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4. | Tserel L |
| 22205703 | Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite. | Emara M |
| 22396536 | Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins. | Pathak SK |
| 23019323 | The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen-presenting cells. | Manzo C |
Pathway
| Pathway Name | Organism |
|---|---|
| Butyrophilin (BTN) family interactions | Homo sapiens |
| CD209 (DC-SIGN) signaling | Homo sapiens |
| RSV-host interactions | Homo sapiens |
UniLectin
| UniProt |
|---|
| Q9NNX6 |
CarboGrove
- Lectin Name
- DC-SIGN
- Common Name
- DC-SIGN
- Automated Analysis report (Top 10 high affinity glycans)
- Array Source
- Microbial
- Protein Source
- Investigator Provided
- Concentration (ug/mL)
-
G26425MP
G25559RS
G32046JJ
G48796BQ
G64541AU
G39023AU
G61491DK
G07682RX
G00052MO
G53402KW
G00051MO
