GlyCosmos Portal

Bos taurus (domestic cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (2220) Glycans (1011) Glycoproteins (1219) Lectins (76) Pathways (548)

Displaying entries **226 - 250** of **548** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LN00 A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 D8KXU9 E1B7I9 E1B8P9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1N339 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 P0CG53 P0CH28 P46196 P62992 P63048 Q3T0F9	AFGF CBL ERK2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 FRS2 Fgf4 GRB2 HBGF-1 MAPK1 MAPK3 PRKM1 PTPN11 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Dopamine Neurotransmitter Release Cycle	Calcium/calmodulin dependent serine protein kinase Complexin-1 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Solute carrier family 18 (Vesicular monoamine), member 2 Synapsin-1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Unc-13 homolog B Vesicle-associated membrane protein 2	A0A3Q1LPV4 A0A3Q1LQ22 A0A3Q1LZT1 A0A3Q1M5L6 A0A3Q1MBH3 A0A452DHU4 B0JYP2 E1BIA1 F1MCX7 F1N7B7 P11023 P32850 P48018 P61763 P63026 Q0IIL7 Q17QQ3 Q2KIB6 Q32LM6	CASK CPLX1 LIN7A LIN7B LIN7C PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RIMS1 SLC18A2 SNAP25 STX1A STXBP1 SYB2 SYN1 SYT1 UNC13B UNC18A VAMP2
Cross-presentation of soluble exogenous antigens (endosomes)	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CD207 molecule Fc gamma receptor Ia Mannose receptor C type 2 Mannose receptor C-type 1 Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta	A0A3Q1M5H7 A0A3S5ZP99 A1L5A6 A7MBA2 E1BB51 F1MBI1 F1MLV1 F1MWE0 F1MWM8 F1MXE4 F1MYH8 G5E589 P33672 P56701 P62194 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2YDE4 Q32KL2 Q3MHN0 Q3T030 Q3T0X5 Q3T0Y5 Q3T108 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9K0	ADRM1 CD207 FCGR1A MRC1 MRC2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 SUG1 TRAP2
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated-binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1M2L5 A6QLU3 E1BCP6 E1BCV1 E1BE66 F1MEQ7 F1MJE0 F1MYM3 F1N261 P23727 P32871 P48617	EPO EPOR GAB1 IRS2 JAK2 LYN PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor	A0A3Q1LQ48 A0A3Q1MAT2 A0A3Q1MQZ8 E1B7W0 F1MGA6 F6R653 G3X6S2 Q28044 Q28838	ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3
Insulin receptor recycling	ATPase H+ transporting V0 subunit e2 Cathepsin D Insulin-degrading enzyme Insulin Receptor-type tyrosine-protein phosphatase F Tyrosine-protein kinase receptor Tyrosine-protein phosphatase non-receptor type V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1	A0A3Q1MS24 A0A452DI38 A0A452DJ67 A4IFJ9 A5PJB2 A6QQN2 A7MBJ4 E1BGJ7 E1BMV6 F1MMR6 F1MV64 O46563 O97681 P11019 P21282 P31404 P31407 P31408 P40682 P61420 P79251 P81103 Q0VCV6 Q1RMS1 Q24K02 Q28029 Q2KJB6 Q2TA24 Q32LB7	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6G ATP6G1 ATP6H ATP6IP1 ATP6N1B ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H CTSD IDE INS INSR LOC101904667 PTPN1 PTPRF SVOPL TCIRG1 VATC VATF VPATPD
Keratinization	DSC1 protein Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoplakin IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein Junction plakoglobin KRT15 protein KRT32 protein KRT4 protein KRT82 protein KRTAP1-1 protein KRTAP4-7 protein Keratin 14 Keratin 16 Keratin 18 Keratin 23 Keratin 24 Keratin 2 Keratin 31 Keratin 31 Keratin 33A Keratin 36 Keratin 37 Keratin 39 Keratin 3 Keratin 77 Keratin 79 Keratin 83 Keratin 84 Keratin 85 Keratin 86 Keratin 9 Keratin associated protein 19-5 Keratin associated protein 3-1 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 17 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 26 Keratin, type I cytoskeletal 27 Keratin, type I cytoskeletal 28 Keratin, type I cytoskeletal 40 Keratin, type II cuticular Hb1 Keratin, type II cytoskeletal 1 Keratin, type II cytoskeletal 5 Keratin, type II cytoskeletal 72 Keratin, type II cytoskeletal 73 Keratin, type II cytoskeletal 74 Keratin, type II cytoskeletal 75 Keratin, type II cytoskeletal 78 Keratin, type II cytoskeletal 7 Keratin, type II cytoskeletal 80 Keratin, type II cytoskeletal 8 Keratin-associated protein 10-8 Keratin-associated protein 12-1-like Keratin-associated protein 12-1-like Keratin-associated protein 12-2 Keratin-associated protein 3-3 Keratin-associated protein 3-3 Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein LOC618938 protein LOC787225 protein Plakophilin 1 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A3Q1LFA4 A0A3Q1LJB2 A0A3Q1LP03 A0A3Q1LQD4 A0A3Q1LSL9 A0A3Q1LUM3 A0A3Q1LYD7 A0A3Q1LZF2 A0A3Q1M0F6 A0A3Q1M0W3 A0A3Q1M139 A0A3Q1M4F4 A0A3Q1M8D5 A0A3Q1MB50 A0A3Q1MDN1 A0A3Q1MEE6 A0A3Q1MFR3 A0A3Q1MLT3 A0A3Q1MN32 A0A3Q1MPF8 A0A3Q1MQC4 A0A3Q1MYR8 A0A3Q1N0A2 A0A3Q1N1L4 A0A3Q1N3D2 A0A3Q1NF50 A0A3Q1NHC3 A0A452DI61 A0A452DIJ6 A0JND2 A3KMY1 A3KN27 A4IFP2 A5D7M6 A5PJJ0 A5PJJ4 A6H712 A6QNX5 A6QNZ7 A6QP35 A6QP90 A6QR67 A7E345 A7YWJ9 A7YWK3 A7YWM2 E1B898 E1B9D7 E1BAH7 E1BFG1 E1BIW5 E1BKT9 E1BM91 F1MC11 F1MFC2 F1MFW9 F1MI65 F1MIW8 F1MJ11 F1MKE7 F1MPK1 F1MTA9 F1MU12 F1MUY2 F1MXJ3 F1MZF2 F1N362 F1N3T1 F1N566 F6RZX2 F6S1Q0 G3MX57 G3MX98 G3MYE1 G3MZ71 G3N073 G3N0V2 G3N156 G3N2U6 G3X7W8 M0QVY0 P08728 Q05B44 Q05B46 Q08D91 Q0P5J4 Q0P5J6 Q0VD04 Q148H4 Q148H6 Q148H8 Q148I8 Q17QL7 Q24JX9 Q29S21 Q8SPJ1	DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KRT1 KRT10 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT2 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33A KRT36 KRT37 KRT39 KRT4 KRT40 KRT5 KRT6B KRT7 KRT72 KRT73 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT86 KRT9 KRTAP1-1 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP19-5 KRTAP24-1 KRTAP27-1 KRTAP3-1 KRTAP3-3 KRTAP4-7 KRTAP8-1 LOC100294937 LOC100300014 LOC101902114 LOC112442669 LOC112446984 LOC112448008 LOC132346256 LOC507184 LOC616413 LOC618359 LOC618938 LOC787051 LOC787225 LOC787600 PKP1 PKP4
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium channel subfamily K member Potassium two pore domain channel subfamily K member 16	E1BEH1 Q8HZT2	KCNK16 KCNK17
Organic anion transporters	Citrate transport protein Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial glutamate carrier 1 Sodium-coupled monocarboxylate transporter 1 Solute carrier family 17 member 1 Solute carrier family 17 member 5 Solute carrier family 17 member 8 Solute carrier family 25 member 10 Solute carrier family 5 member 5 Vesicular glutamate transporter 1 Vesicular glutamate transporter 2	A0A3Q1MTZ5 A4FV52 A6QLI1 C8KIL7 E1B7R3 E1BA07 F1MBS4 F1MT46 F1N6Z8 P22292 Q08DK4	GC1 SLC17A1 SLC17A5 SLC17A6 SLC17A7 SLC17A8 SLC20A4 SLC25A1 SLC25A10 SLC25A11 SLC25A22 SLC5A5 SLC5A8 SMCT1 VGLUT1 VGLUT2
Phase 2 - plateau phase	Calcium voltage-gated channel auxiliary subunit alpha2delta 2 KCNE1-like MinK-related peptide 3 Potassium voltage-gated channel subfamily E member 1 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily E member 3 Potassium voltage-gated channel subfamily KQT member 1 Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit	A0A3Q1LKG2 A0A3Q1MT75 A2VDV8 E1BGG9 E1BIG3 E1BLK4 F1MV40 F1MX37 F1N5T3 Q0IIF1 Q2KHV0 Q2NKS7 Q9MZL5 Q9MZL7	CACNA1C CACNA2D2 CACNB1 CACNB2 CACNG4 CACNG6 CACNG7 CACNG8 KCNE1 KCNE1L KCNE2 KCNE3 KCNE4 KCNE5 KCNQ1
EPHA-mediated growth cone collapse	Neuronal guanine nucleotide exchange factor Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0JNB0 A7MB57 E1BIM8 F1N261 P61585 Q08DA6	ARHA FYN LYN NGEF RHO12 RHOA SRC YES1
PD-1 signaling	BOLA-DQA1 protein BoLA-DR-alpha CD4 molecule Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II antigen Major histocompatibility complex, class II, DY alpha Programmed cell death 1 ligand 2 Programmed cell death-ligand 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain TRAV29-1*01 Tyrosine-protein kinase CSK Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type	A0A3Q1M088 A0A3Q1M2W6 A0A3Q1M3D2 A0A3Q1M739 A0A3Q1MT21 A6H6Y1 A6QQE7 C5NU11 E1BLZ1 F1MJK4 F1MJU5 F1ML60 F1N0X9 F1N339 G3MWT2 G8JL01 Q0VBZ0 Q0VCU4 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BoLA-DIB BoLA-DRA BoLA-DYB CD247 CD274 CD3D CD3E CD3G CD4 CSK DYB HLA-DRA LCK LOC100848815 PD-L1 PDCD1LG2 PTPN11 PTPN6 TRAV29-1
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Acetylcholine receptor subunit delta Acetylcholine receptor subunit epsilon Acetylcholine receptor subunit gamma Cholinergic receptor nicotinic beta 2 subunit Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-4	A0A3Q1MJN8 E1BHK0 F1MC93 F1MYI7 P02715 P04759 P13536	CHRNA3 CHRNA4 CHRNB2 CHRNB4 CHRND CHRNE CHRNG
Formation of the beta-catenin:TCF transactivating complex	ASH2 like, histone lysine methyltransferase complex subunit BCL9 like BCL9 transcription coactivator Catenin beta-1 Cell division cycle 73 Histone H2A.J Histone H2A.V Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1 Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.2 Histone H3.3 Histone H3 Histone H4 Histone acetyltransferase Histone deacetylase 1 Lymphoid enhancer binding factor 1 Menin Pygopus family PHD finger 1 RBBP5 protein RNA polymerase-associated protein LEO1 RuvB-like helicase TLE family member 1, transcriptional corepressor TLE family member 2, transcriptional corepressor TLE family member 3, transcriptional corepressor TLE family member 4, transcriptional corepressor Telomerase reverse transcriptase Transcription activator BRG1 Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7 Transformation/transcription domain associated protein histone acetyltransferase histone acetyltransferase	A0A3Q1LJY1 A0A3Q1LTE2 A0A3Q1LW99 A0A3Q1M3K5 A0A3Q1M6V2 A0A3Q1MAN6 A0A3Q1MBN5 A0A3Q1MF62 A0A3Q1MG64 A0A3Q1MIR9 A0A3Q1MZ99 A4FUE3 A7MBG8 A7Z019 E1B8D6 E1B8G9 E1BEP4 E1BH22 E1BHL3 E1BKJ5 E1BPF3 E1BPQ8 F1MD32 F1MHP8 F1MJS2 F1ML22 F1MUU9 F1MXC3 F2Z4F9 F2Z4J1 G3MWX6 G3MYB1 G3N0M9 G5E6I9 P62803 P62808 P68432 P84227 Q0P5I0 Q0VBX4 Q0VCX4 Q2KII5 Q32LA7 Q32PJ8 Q32S29 Q3ZBX9 Q5E9F8	ASH2L BAF190A BCL9 BCL9L BRG1 CDC73 CREBBP CTNNB1 EP300 H2AC12 H2AC18 H2AC21 H2AC6 H2AJ H2AV H2AZ2 H2B H2BC26 H2BC5 H3-3A H3-3B H3F3A H3F3B HDAC1 HIST1H2BI KAT5 LEF1 LEO1 LOC100297725 LOC528006 MEN1 PYGO1 RBBP5 RUVBL1 SMARCA4 SNF2B SNF2L4 TCF7 TCF7L1 TCF7L2 TERT TLE1 TLE2 TLE3 TLE4 TRRAP
Chylomicron remodeling	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein B Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Lipoprotein lipase	A0A140T881 A0A3Q1MPP4 A4FUZ9 E1BNR0 F1N3Q7 P11151 P15497 P19034 P19035 P81644	APOA1 APOA2 APOA4 APOA5 APOB APOC2 APOC3 APOE GPIHBP1 LPL
NIK-->noncanonical NF-kB signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme Ubc12 NFKB2 protein Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta RELB proto-onco, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M118 A0A3Q1MJI4 A1L5A6 A3KN22 A7MBA2 A7MBB7 E1BL08 F1MBB0 F1MBI1 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2YDE4 Q32KL2 Q3MHN0 Q3T030 Q3T0X5 Q3T0Y5 Q3T108 Q3ZBD0 Q3ZBG0 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9K0 Q95KV1	ADRM1 CHUK CUL1 FBXW11 IKKA MAP3K14 NFKB2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RELB RPS27A SKP1 SKP1A SUG1 TRAP2 UBA3 UBA52 UBA80 UBB UBC UBC12 UBCEP1 UBCEP2 UBE2M
Retrograde transport at the Trans-Golgi-Network	ADP-ribosylation factor-like protein 1 ADP-ribosylation factor-related protein 1 Arfaptin-2 Beta-soluble NSF attachment protein Cation-dependent mannose-6-phosphate receptor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 GRIP and coiled-coil domain containing 1 GRIP and coiled-coil domain containing 2 Gamma-soluble NSF attachment protein Golgin A1 Golgin A4 Insulin like growth factor 2 receptor NSF attachment protein alpha Perilipin Protein RIC1 homolog Protein SYS1 homolog RAB6A, member RAS onco family RAB6B, member RAS onco family RAB9A, member RAS onco family RAB9B, member RAS onco family RGP1 homolog, RAB6A GEF complex partner 1 Rab9 effector protein with kelch motifs Rho related BTB domain containing 3 Short coiled-coil protein Short coiled-coil protein Syntaxin 10 Syntaxin 16 Syntaxin-6 TATA element modulatory factor 1 Trans-golgi network protein 2 Vacuolar protein sorting-associated protein 51 homolog Vacuolar protein sorting-associated protein 52 homolog Vacuolar protein sorting-associated protein 53 homolog Vacuolar protein sorting-associated protein 54 Vesicle transport through interaction with t-SNAREs 1A Vesicle-associated membrane protein 4 Vesicle-fusing ATPase	A0A3Q1LSE5 A0A3Q1LTE3 A0A3Q1M2K6 A0A3Q1M5V0 A0A3Q1M9K7 A0A3Q1MBS7 A0A3Q1MPM7 A0A452DHU1 A0A452DKB6 A2VE18 A7YWK8 E1BB16 E1BDC9 E1BFF9 E1BGA6 E1BIQ3 E1BJW7 E1BJZ4 E1BK29 E1BQ02 F1MIE6 F1MJ84 F1MKR0 F1MLE3 F1MND0 F1MQ89 F1MUW6 F1N5R4 F1N686 F6Q334 F6RJ01 G3N173 P11456 P81126 Q08DW1 Q0VCB4 Q1RMQ3 Q2YDM1 Q32L97 Q32LJ2 Q3MHG0 Q3SX32 Q3ZCL5 Q5EA50	ARFIP2 ARFRP1 ARL1 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 GCC1 GCC2 GOLGA1 GOLGA4 IGF2R M6PR M6PRBP1 NAPA NAPB NAPG NSF RAB6A RAB6B RAB9A RAB9B RABEPK RGP1 RHOBTB3 RIC1 SCOC SNAPB STX10 STX16 STX6 SYS1 TMF1 VAMP4 VPS51 VPS52 VPS53 VPS54 VTI1A
Negative regulation of the PI3K/AKT network	Phosphatase and tensin homolog	F1MDX9	PTEN
NTF3 activates NTRK3 signaling	Neurotrophin-3 Tyrosine-protein kinase receptor	G3N3T6 Q08DT3	NTF3 NTRK3
Phase I - Functionalization of compounds	Aldehyde dehydrogenase Alpha/beta hydrolase fold-3 domain-containing protein Amine oxidase [copper-containing] 3 Amine oxidase Amine oxidase Amine oxidase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like CYB5B protein Carbonyl reductase (NADPH) Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 family 2 subfamily B member 6 Epoxide hydrolase Mitochondrial amidoxime reducing component 1 Mitochondrial amidoxime reducing component 2 NAD(P)H dehydrogenase, quinone 2 NADH-cytochrome b5 reductase 3 Primary amine oxidase, liver isozyme	A0A3Q1LGS8 A0A3Q1LKX3 A0A3Q1LZ03 A0A3Q1M7J3 A0A3Q1MQJ1 A0A3Q1MU42 A0A452DHX8 E1BC09 F1MFG7 F1MI11 F1ML85 F1MU22 F1MYL2 F1N015 G3X6I4 G3X6X4 G5E6I5 P07514 Q0P5F6 Q0VC97 Q1LZH1 Q29437 Q29RV2 Q3MHQ1 Q3SZT2 Q3T047 Q3ZCJ6 Q9TTK6	AADAC ABP1 AHR ALDH3A1 AOC1 AOC2 AOC3 ARNT ARNT2 BPHL CBR3 CES1 CES2 CES3 CMBL CYB5B CYB5R3 CYP2B6 CYP3A28 CYP3A4 CYP3A5 CYP3A74 DIA1 EPHX1 LOC100138645 MARC2 MOSC2 MTARC1 MTARC2 NQO2
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member 1 Potassium channel subfamily K member	E1B9M4 Q0P5A0	KCNK1 KCNK7
Nuclear signaling by ERBB4	Estrogen receptor Gamma-secretase subunit APH-1 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Nicastrin Presenilin-1 Presenilin-2 Receptor protein-tyrosine kinase Signal transducer and activator of transcription 5A Tyrosine-protein kinase WW domain-containing oxidoreductase Yes1 associated transcriptional regulator	A0A3Q1LNM1 A0A3Q1LVN4 A0A3Q1MBH7 A0A3Q1MDC6 A0A3Q1MKB4 E1BIM8 F1MK73 P49884 Q5G235 Q95115 Q9XT96 Q9XT97	APH1A APH1B ERBB4 ESR ESR1 MGF NCSTN NR3A1 PEN2 PSEN1 PSEN2 PSENEN SRC STAT5A WWOX YAP1
Aflatoxin activation and detoxification	Cytochrome P450 1A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 family 2 subfamily A member 13 Dipeptidase 1 Dipeptidase Glutathione S-transferase 3, mitochondrial Glutathione hydrolase 7 Glutathione hydrolase Glutathione hydrolase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 N-acyl-aliphatic-L-amino acid amidohydrolase NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein	A0A3Q1LZ03 E1BIR2 F1MHN9 F1MR63 F1MXY2 F1MYJ3 F1MZC0 F1N6I4 G3MYH2 G3N2D8 G3X6I4 Q0V8L2 Q29RV2 Q2KJG4 Q3SZM7 Q3T047 Q3T100	ACY1 AKR7A2 CYP1A2 CYP2A13 CYP3A28 CYP3A4 CYP3A5 CYP3A74 DPEP1 DPEP2 GGT1 GGT5 GGT7 GGTL3 MGST1 MGST2 MGST3
Scavenging by Class A Receptors	Apolipoprotein B Collectin-11 Collectin-12 MBL associated serine protease 1	A6QP79 E1BNR0 F1MVS9 Q17QH6	APOB CLP1 COLEC11 COLEC12 MASP1	G27025MB G70323CJ G82576YO
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 BCAR1 scaffold protein, Cas family member C22H3ORF10 protein Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein Cytoplasmic protein Cytoplasmic protein Dedicator of cytokinesis 1 Engulfment and cell motility 2 Focal adhesion kinase 1 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin beta Integrin subunit alpha V MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 NCK associated protein 1 like Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proto-oncogene vav Rho-associated protein kinase 2 Rho-associated protein kinase SH2 domain containing adaptor protein B SH2D2A protein SHC adaptor protein 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Wiskott-Aldrich syndrome protein family member cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase non-specific protein-tyrosine kinase non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LTT9 A0A3Q1LVP1 A0A3Q1M0G8 A0A3Q1M614 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MQ07 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRN2 A0A3Q1MTW8 A0A3Q1MW77 A0A3Q1MXS2 A0A3Q1N508 A0A3Q1NMX4 A0A452DHY1 A0A452DJE2 A0JNB0 A2VDK6 A6H720 A7Z041 A8YXX8 E1B876 E1BBD2 E1BIM8 E1BLY9 E1BN47 E1BPY0 E1BQ32 F1MF50 F1MFD1 F1MIX6 F1MTN1 F1MWF1 F1MX60 F1MYM3 F1N5N3 G3X793 O46521 O46522 P00517 P15691 P23726 P23727 P32871 P61585 Q08DN7 Q0IIJ3 Q1LZB2 Q2KJ93 Q3SYZ2 Q3T149 Q5E9Q6 Q5EAD0 Q76LV2	ABI1 ABI2 ARHA AXL BAIAP2 BCAR1 C22H3ORF10 CDC42 CRK CYBA CYBB CYFIP1 CYFIP2 DOCK1 ELMO2 FYN HSP27 HSP90A HSP90AA1 HSPB1 HSPCA ITGAV ITGB3 KDR MAPK11 MAPK13 MAPK14 MAPKAPK2 MAPKAPK3 NCF1 NCF2 NCF4 NCK1 NCK2 NCKAP1L PAK2 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKACA PRKACB PTK2 PTK2B PXN RHO12 RHOA ROCK1 ROCK2 SH2D2A SHB SHC2 SRC VAV1 VAV2 VAV3 VEGF VEGFA WASF1 WASF2 WASF3

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