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Synthesis of PIPs at the Golgi membrane

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1660514

PubChem

R-HSA-1660514

Description

At the Golgi membrane, phosphatidylinositol 4-phosphate (PI4P) is primarily generated from phosphorylation of phosphatidylinositol (PI). Other phosphoinositides are also generated by the action of various kinases and phosphatases such as: phosphatidylinositol 3-phosphate (PI3P), phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2), phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) (Godi et al. 1999, Minogue et al. 2001, Rohde et al. 2003, Sbrissa et al. 2007, Sbrissa et al. 2008, Domin et al. 2000, Arcaro et al. 2000).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 11 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O00443	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	PIK3C2A	view
O75747	Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma	PIK3C2G	view
P42356	Phosphatidylinositol 4-kinase alpha	PI4KA PIK4 PIK4CA	view
P61204	ADP-ribosylation factor 3	ARF3	view
Q01968	Inositol polyphosphate 5-phosphatase OCRL	OCRL OCRL1	view
Q08AM6	Protein VAC14 homolog	TAX1BP2 TRX VAC14	view
Q92562	Polyphosphoinositide phosphatase	FIG4 KIAA0274 SAC3	view
Q99570	Phosphoinositide 3-kinase regulatory subunit 4	PIK3R4 VPS15	view
Q9NRR6	Phosphatidylinositol polyphosphate 5-phosphatase type IV	INPP5E	view
Q9NTJ5	Phosphatidylinositol-3-phosphatase SAC1	KIAA0851 SAC1 SACM1L	view

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