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Synthesis of PIPs at the early endosome membrane

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1660516

PubChem

R-HSA-1660516

Description

At the early endosome membrane, phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is generated in two steps from phosphatidylinositol 3,4-bisphosphate PI(3,4)P2 by the action of various kinases and phosphatases (Sbrissa et al. 2007, Sbrissa et al. 2008, Cao et al. 2007, Cao et al. 2008, Arcaro et al. 2000, Kim et al. 2002).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 10** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O00443	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	PIK3C2A	view
Q08AM6	Protein VAC14 homolog	TAX1BP2 TRX VAC14	view
Q13614	Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2	KIAA1073 MTMR2	view
Q92562	Polyphosphoinositide phosphatase	FIG4 KIAA0274 SAC3	view
Q96PE3	Inositol polyphosphate-4-phosphatase type I A	INPP4A	view
Q99570	Phosphoinositide 3-kinase regulatory subunit 4	PIK3R4 VPS15	view
Q9NXD2	Myotubularin-related protein 10	MTMR10	view
Q9NYA4	Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4	KIAA0647 MTMR4 ZFYVE11	view
Q9Y2H2	Phosphatidylinositide 4-phosphatase SAC2	INPP5F KIAA0966 MSTP007 MSTP047 SAC2	view
Q9Y2I7	1-phosphatidylinositol 3-phosphate 5-kinase	KIAA0981 PIKFYVE PIP5K3	view

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