RHO GTPases Activate NADPH Oxidases

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
NOX2 complexNOX2 complex:RAC1:GTPRAC1:GTPTPNHTPNO2O2.-H+RAC2:GTPNOX2 complex:RAC2:GTPNOX2 complexO2O2.-NOX1 complex:RAC1:GTPNOX1 ComplexNOX3 complex:RAC1:GTPNOX3 ComplexATPADPPIPI3Pp-S-345-NCF1:NCF2:NCF4NCF1:NCF2:NCF4PIN1:p-S-345-NCF1:NCF2:NCF4PIN1PIN1:p-S-6S-NCF1:NCF2:NCF4S100A8:S100A9:AA:Ca2+NOX2 complex:S100A8:S100A9:Ca2+
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025