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Transcriptional regulation of brown and beige adipocyte differentiation by EBF2

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
EBF2, EBF2:Blnc1 lncRNA:HNRNPU:PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, PPARGC1A gene)EBF2, EBF2:Blnc1 lncRNA:HNRNPU:Activated PPARG:RXRA:PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, PPARGC1A gene)Brown,beige adipocyte-specific coactivators of PPARG:RXRARXRA natural ligandsPPARG:RXRAPPARG natural ligandsPRDM16 geneMEL1DIO2 geneDIO2Blnc1 lncRNAEBF2:Blnc1 lncRNA:HNRNPUSAF-AEBF2PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, COX7A1 gene, DIO2 gene, ELOVL3 gene, PPARGC1A gene)EBF2, EBF2:Blnc1 lncRNA:HNRNPU:PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, COX7A1 gene, DIO2 gene, ELOVL3 gene, PPARGC1A gene)EBF2,EBF2:Blnc1 lncRNA:HNRNPUEBF2, EBF2:Blnc1 lncRNA:HNRNPU: PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, DIO2 gene, ELOVL3 gene)ZNF423:EBF2, EBF2:Blnc1 lncRNA:HNRNPU:PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, DIO2 gene, ELOVL3 gene)OAZZNF423:EBF2, EBF2:Blnc1 lncRNA:HNRNPU:PPARA gene, UCP1 gene, (CIDEA gene, DIO2 gene)NuRD:ZNF423:EBF2,EBF2:Blnc1 lncRNA:HNRNPU:PPARA gene, UCP1 gene, (CIDEA gene, DIO2 gene)NuRD complexZNF423:p-2S-SMAD1:p-2S-SMAD1:SMAD4p-2S-SMAD1:p-2S-SMAD1:SMAD4PPARA genePPARAUCP1 geneUCP1CIDEA geneCIDEACOX7A1 geneCOX7A1PPARGC1A genePGC1AELOVL3 geneELOVL3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 11 - 19 of 19 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q15788 Nuclear receptor coactivator 1
  • BHLHE74
  • NCOA1
  • SRC1
 view
Q2M1K9 Zinc finger protein 423
  • KIAA0760
  • NPHP14
  • OAZ
  • ZNF423
 view
Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta
  • PERC
  • PGC1
  • PGC1B
  • PPARGC1
  • PPARGC1B
 view
Q86YP4 Transcriptional repressor p66-alpha
  • GATAD2A
 view
Q8WXI9 Transcriptional repressor p66-beta
  • GATAD2B
  • KIAA1150
 view
Q92769 Histone deacetylase 2
  • HDAC2
 view
Q9HAZ2 Histone-lysine N-methyltransferase PRDM16
  • KIAA1675
  • MEL1
  • PFM13
  • PRDM16
 view
Q9HB03 Very long chain fatty acid elongase 3
  • CIG30
  • ELOVL3
 view
Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • LEM6
  • PGC1
  • PGC1A
  • PPARGC1
  • PPARGC1A
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025