Interferon gamma signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
IFNGR1:JAK1:INFGR2:JAK2IFNG:IFNGR1:JAK1:IFNGR2:JAK2IFNG dimerIFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitorsJAK1,2 inhibitorsIFNG dimer:IFNG inhibitorsIFNG inhibitorsIFNG:IFNGR1:JAK1:IFNGR2:p-JAK2ADPATPIFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2Ybx1P62960P62960STAT1 bound to p-IFNGR1Stat1p-STAT1(Y701) bound to p-IFNGR1p-STAT1 dimer bound to p-IFNGR1IFNG-activated factor (GAF)p-STAT1 homodimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025