GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **499** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Integrin alpha pat-2 Uncharacterized integrin beta-like protein C05D9.3	P34446 Q9GYK2	C05D9.3 pat-2	Caenorhabditis elegans
ISG15 antiviral mechanism	Beclin homolog Calponin-homology (CH) domain-containing protein E1 ubiquitin-activating enzyme E3 ubiquitin-protein ligase ari-1.1 E3 ubiquitin-protein ligase Eukaryotic initiation factor 4A Eukaryotic translation initiation factor 2-alpha kinase pek-1 Eukaryotic translation initiation factor 4E-1 Eukaryotic translation initiation factor 4E-2 Eukaryotic translation initiation factor 4E-3 Eukaryotic translation initiation factor 4E-4 Eukaryotic translation initiation factor 4E-5 HECT domain-containing protein Helicase ATP-binding domain-containing protein MIF4G domain-containing protein Mitogen-activated protein kinase mpk-1 Polyubiquitin-A Protein kinase domain-containing protein Protein phosphatase ppm-1.A RNA helicase RNA helicase Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 UBC core domain-containing protein Ubiquitin carboxyl-terminal hydrolase usp-48 Ubiquitin-conjugating enzyme E2 13 Ubiquitin-conjugating enzyme E2 ubc-18 Ubiquitin-like domain-containing protein X-linked retinitis pigmentosa GTPase regulator homolog	A0A061ACQ8 A0A486WX07 D3YT30 G5ECC7 G5EEM6 O01965 O44820 O45551 O61955 P0CG71 P27639 P39745 P56570 Q19192 Q19775 Q20617 Q20935 Q20977 Q21633 Q21693 Q22592 Q22888 Q27481 Q5DX34 Q93413 Q95XX0 Q9BL11 Q9BL61 Q9NAD6 U4PBJ9	CELE_F52C6.3 CELE_F57B9.3 CELE_T12G3.2 CELE_Y92H12A.2 ari-1.1 atg-6 bec-1 drh-3 eif-4A3 fln-1 glo-4 herc-1 ife-1 ife-2 ife-3 ife-4 ife-5 ifg-1 inf-1 mpk-1 pek-1 ppm-1.A sta-1 sta-2 stat-b sur-1 tap-1 uba-1 ubc-13 ubc-18 ubc-24 ubia ubq-1 usp-48	Caenorhabditis elegans
IRE1alpha activates chaperones	Serine/threonine-protein kinase/endoribonuclease ire-1	Q09499	ire-1	Caenorhabditis elegans
Hydrolysis of LPC	PhosphoLipase A2 Group	Q21515	plag-15	Caenorhabditis elegans
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase A EF-hand domain-containing protein Hyaluronidase Na(+)/H(+) exchanger protein 7	G5EBK1 G5ECE8 Q22492 Q23643 Q95Q32	CELE_Y105E8B.9 Chnase chhy-1 chpf-1 hex-1 nhx-7 pbo-4	Caenorhabditis elegans	G35674CY
Hyaluronan biosynthesis and export	Multidrug resistance-associated protein 5	G5EE72	mrp-5	Caenorhabditis elegans	G35674CY
Histamine receptors	Dopamine receptor 2 G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Muscarinic acetylcholine receptor gar-3	E7EM37 G5EGH0 O45601 Q9U7D5	dop-2 dop-2L gar-3 ser-4 tag-89	Caenorhabditis elegans
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Proton-gated ion channel subunit pbo-6	G5EDF1 P48181 P48182 Q19351 Q23022 Q23355 Q27218 Q93149 Q93329 Q9N4M3 Q9N587	acr-12 acr-2 acr-3 acr-6 acr-8 lev-1 lev-7 lev-8 lgc-3 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor (51.1 kD) (Acr-22) Acetylcholine receptor subunit alpha-type acr-5 Acetylcholine receptor subunit alpha-type deg-3 Acetylcholine receptor subunit alpha-type des-2 Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Betaine receptor acr-23 Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-gated ion channel 4 Neur_chan_LBD domain-containing protein Neur_chan_memb domain-containing protein Neurotransmitter-gated ion-channel ligand binding domain protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Proton-gated ion channel subunit pbo-6	A0A3P6P985 B1Q281 G5EDF1 G5EE87 G5EG88 G5EGR1 H2KML8 O18228 O44452 O61216 O61519 O61520 O76554 P48181 P48182 P54244 P54245 P54246 Q19351 Q23022 Q23355 Q27218 Q65XS8 Q6BEQ0 Q93149 Q93329 Q95Y94 Q9N4M3 Q9N587 V6CJ96	acr-12 acr-2 acr-20 acr-21 acr-22 acr-23 acr-24 acr-25 acr-3 acr-4 acr-5 acr-6 acr-8 deg-3 des-2 lev-1 lev-7 lev-8 lgc-10 lgc-11 lgc-12 lgc-3 lgc-30 lgc-31 lgc-4 lgc-5 lgc-6 lgc-7 lgc-8 lgc-9 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Highly calcium permeable nicotinic acetylcholine receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Proton-gated ion channel subunit pbo-6	G5EDF1 P48181 P48182 Q19351 Q23022 Q23355 Q27218 Q93149 Q93329 Q9N4M3 Q9N587	acr-12 acr-2 acr-3 acr-6 acr-8 lev-1 lev-7 lev-8 lgc-3 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Heme signaling	C-type lectin domain-containing protein C-type lectin domain-containing protein Protein vem-1 Proton-coupled folate transporter SoLute Carrier family Related SoLute Carrier family Related Solute carrier family 46 member 3	A0A061AD52 G5EFM5 H2KZC0 Q20236 Q7YZW5 Q9UAZ6 Q9XWL3	C25G4.17 clec-185 slc-46A slc-46a slcr-46.1 slcr-46.2 slcr-46.3 vem-1	Caenorhabditis elegans
Heme degradation	ABC transmembrane type-1 domain-containing protein ABC transporter domain-containing protein ABC transporter family G domain-containing protein Fatty acid-binding protein homolog 5 Fatty acid-binding protein homolog 6 Fatty acid-binding protein homolog 7 Fatty acid-binding protein homolog 8 Multidrug resistance protein mrp-7 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member	D7SFK1 G5EFP3 O01812 O01814 O02323 O02324 Q19048 Q19585 Q20943 Q3S1M2 Q93550 Q9U2G5 Q9XW61	CELE_F21G4.1 abcx-1 lbp-5 lbp-6 lbp-7 lbp-8 mrp-1 mrp-2 mrp-3 mrp-4 mrp-7 mrp-8 wht-5	Caenorhabditis elegans
Hedgehog 'on' state	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 BTB and MATH domain-containing protein 40 BTB and MATH domain-containing protein 41 BTB and MATH domain-containing protein 42 BTB domain-containing protein Cullin-3 MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Protein maternal effect lethal 26 Protein patched homolog 1 Protein patched homolog 3 RING-box protein 1 Speckle-type POZ protein homolog Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	H2KYJ3 H2L0G5 O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P34371 P34568 P37165 P41886 P46502 P49632 P90868 P91477 Q04908 Q09614 Q10920 Q17391 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q23457 Q27488 Q94420 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9NF14 Q9XTT9 Q9XUV0	CELE_F35G12.12 bath-40 bath-41 bath-42 bath-43 bath-44 cul-3 mel-26 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 ptc-1 ptc-3 rbx-1 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 spop-1 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
HSP90 chaperone cycle for SHRs	DNaJ domain (Prokaryotic heat shock protein) DNaJ domain (Prokaryotic heat shock protein) DUF148 domain-containing protein Heat shock protein 90 Heat shock protein hsp-1 Stress-induced-phosphoprotein 1	G5EC99 O16259 O16303 O45502 P09446 Q18688	CELE_F11F1.1 daf-21 dnj-12 dnj-19 hsp-1 hsp70a sti-1	Caenorhabditis elegans
HSF1-dependent transactivation	Calcium/calmodulin-dependent protein kinase type II DAF-15 DUF148 domain-containing protein Heat shock factor-binding protein 1 Heat shock protein 90 Heat shock protein Hsp-12.2 Heat shock protein hsp-1 Heat shock transcription factor hsf-1 Target of rapamycin complex subunit lst8 Target of rapamycin homolog	G5EC99 G5EFT5 O62305 P09446 P34328 P91040 Q18688 Q68TI8 Q95Q95 Q9U3B7	CELE_F11F1.1 CeTor daf-15 daf-21 hsb-1 hsf-1 hsp-1 hsp-12.2 hsp12-2 hsp70a let-363 mlst-8 unc-43	Caenorhabditis elegans
HSF1 activation	Co-chaperone protein daf-41 Elongation factor 1-alpha Heat shock protein 90 Heat shock transcription factor hsf-1 Histone deacetylase domain-containing protein Transitional endoplasmic reticulum ATPase homolog 2	G5EFT5 P53013 P54812 Q18688 Q23280 Q9U266	cdc-48.2 daf-21 daf-41 eft-3 eft-4 hda-10 hsf-1 p23	Caenorhabditis elegans
HS-GAG degradation	Alpha-N-acetylglucosaminidase Beta-galactosidase Beta-glucuronidase GlyPicaN Glycoside hydrolase 35 catalytic domain-containing protein Ig-like domain-containing protein InTestinal NeureXin-like LONg Laminin G domain-containing protein Probable syndecan Thioredoxin domain-containing protein Titin homolog	C6KRM7 G4SLH0 G5ECV3 G5EGU4 O45000 O76632 P50605 Q18530 Q22574 Q27526 Q95Q32 Q9NAP6	C03H12.1 CELE_K09E4.4 CELE_T19D12.6 CELE_Y105E8B.9 bgal-1 bgal-2 gpn-1 itx-1 lon-2 rig-5 sdn-1 ttn-1	Caenorhabditis elegans	G01550VL G09546QO
HS-GAG biosynthesis	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 GlyPicaN Heparan sulfate 2-O-sulfotransferase hst-2 Heparan-sulfate 6-O-sulfotransferase Ig-like domain-containing protein InTestinal NeureXin-like LONg Laminin G domain-containing protein Probable syndecan Sulfotransferase domain-containing protein Sulfotransferase domain-containing protein Thioredoxin domain-containing protein Titin homolog UDP-sugar transporter sqv-7	C6KRM7 G4SLH0 G5ECV3 G5EFN7 G5EGU4 O17645 O45000 P50605 Q18530 Q18779 Q22574 Q4TTA0 Q966W3 Q9TZK5	C03H12.1 CELE_T19D12.6 gpn-1 hst-1 hst-2 hst-3.1 hst-3.2 hst-6 itx-1 lon-2 rig-5 sdn-1 sqv-7 ttn-1	Caenorhabditis elegans
HDL remodeling	PhosphoLipase A2 Group	Q21515	plag-15	Caenorhabditis elegans
Growth hormone receptor signaling	Fibronectin type-III domain-containing protein	Q9UB28	let-805	Caenorhabditis elegans
Golgi Associated Vesicle Biogenesis	ADP-ribosylation factor 1-like 1 ADP-ribosylation factor 1-like 2 AP complex mu/sigma subunit domain-containing protein AP complex subunit beta AP complex subunit sigma AP-1 complex subunit gamma AP-1 complex subunit mu-1-I AP-3 complex subunit beta Beta-arrestin arr-1 Carboxypeptidase D Clathrin light chain Dynamin E3 ubiquitin-protein ligase arc-1 Endophilin-A homolog Glutamate carboxypeptidase 2 homolog Huntington interacting protein related 1 J domain-containing protein MHD domain-containing protein N-acetylated-alpha-linked acidic dipeptidase 2 NECAP PHear domain-containing protein PX domain-containing protein PX domain-containing protein Phosphatidylinositol-binding clathrin assembly protein unc-11 Probable clathrin heavy chain 1 Protein YIPF Rab-GAP TBC domain-containing protein Rho-GAP domain-containing protein SNAPIN protein homolog Sorting nexin lst-4 Synaptobrevin-1 Synaptobrevin-like protein 5 Uncharacterized protein F13E6.1 V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein small monomeric GTPase	A0A486WXP9 B1V8A0 C6KRN3 D9PTP5 G5EBE2 G5EBK2 O01755 O02495 O16369 O17590 O44445 O45718 P34351 P34574 P35602 P39055 P51485 P55326 P90961 P91359 P91406 P91857 Q02328 Q09654 Q10943 Q19767 Q8I4E2 Q8T874 Q8WQB3 Q93332 Q94057 Q94231 Q95XH1 Q9GYJ9 Q9N489 Q9N4F3 Q9XZI6	CELE_W02D9.2 F13E6.1 apb-1 apb-3 apg-1 apm-1 aps-1 aps-3 arc-1 arf-1 arf-1.1 arf-1.2 arl-4 arl-6 arr-1 chc-1 clic-1 cpd-1 dnj-25 dyn-1 gcp-2.1 gcp-2.2 hipr-1 lst-4 ncap-1 ocrl-1 rab-5 snb-1 snb-2 snb-5 snb-6 snb-7 snpn-1 snx-1 snx-6 tbc-9 unc-101 unc-11 unc-57 vamp-7	Caenorhabditis elegans
Glyoxylate metabolism and glycine degradation	Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase D-amino-acid oxidase D-aspartate oxidase 1 D-aspartate oxidase 2 D-aspartate oxidase 3 FMN hydroxy acid dehydrogenase domain-containing protein Proline dehydrogenase 1, mitochondrial	B1GRK5 O01739 O02158 O45228 O45307 Q17994 Q19564 Q94055 Q95XG9	CELE_F41E6.5 CELE_T09B4.8 agxt-1 daao-1 ddo-1 ddo-2 ddo-3 got-2.2 prdh-1 prodh	Caenorhabditis elegans
Glycosphingolipid catabolism	Acid ceramidase Alpha-galactosidase Beta-galactosidase Beta-hexosaminidase A Bis(5'-adenosyl)-triphosphatase Glycoside hydrolase 35 catalytic domain-containing protein Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Non-lysosomal glucosylceramidase Putative galactocerebrosidase Putative glucosylceramidase 4 Putative neutral sphingomyelinase Saposin B-type domain-containing protein Saposin B-type domain-containing protein Sphingomyelin phosphodiesterase 2 Sphingomyelin phosphodiesterase 4 Uncharacterized protein	O01893 O02106 O45686 O45870 O76632 Q17540 Q18276 Q18279 Q18758 Q21801 Q22492 Q23498 Q27526 Q95QT2 Q95ZR2 Q9TZA0 Q9UB00	C01B10.9 C29E4.10 CELE_R05D11.9 CELE_R08F11.1 T27F6.6 asah-1 asm-2 bgal-1 bgal-2 gana-1 gba-4 hex-1 klo-1 klo-2 mlt-8 spp-10 spp-8	Caenorhabditis elegans	G09546QO G27025MB G58161NS
Glycosphingolipid biosynthesis	Ceramide glucosyltransferase 2 Ceramide kinase 1 Hexosyltransferase L-Fucosyltransferase Putative UDP-glucuronosyltransferase ugt-60	G5EC84 O61739 P34317 Q8MQG4 Q9TZI1	B0024.15 B0205.4 cerk-1 cgt-2 ugt-60	Caenorhabditis elegans
Glycolysis	ATP-dependent 6-phosphofructokinase 1 ATP-dependent 6-phosphofructokinase 2 Enolase Fructose-bisphosphate aldolase 1 Fructose-bisphosphate aldolase 2 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase 1 Glyceraldehyde-3-phosphate dehydrogenase 2 Glyceraldehyde-3-phosphate dehydrogenase 3 Glyceraldehyde-3-phosphate dehydrogenase 4 Phosphoglucomutase-2 Phosphotransferase Phosphotransferase Phosphotransferase Probable ADP-dependent glucokinase Probable glucosamine-6-phosphate isomerase Probable phosphoglycerate kinase Pyruvate kinase Pyruvate kinase Triosephosphate isomerase	B7WNA0 O45934 P04970 P17329 P17330 P17331 P46563 P54216 P91427 Q10657 Q19440 Q23539 Q27483 Q27527 Q7K707 Q86S40 Q9N4A5 Q9TZL8 Q9XU15 Q9XVJ2	C50D2.7 CELE_Y43F4B.5 T03F6.3 aldo-1 aldo-2 enol-1 gpd-1 gpd-2 gpd-3 gpd-4 gpi-1 hxk-1 hxk-2 hxk-3 pfk-1.1 pfk-1.2 pgk-1 pyk-1 pyk-2 tpi-1	Caenorhabditis elegans	G58161NS

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