GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **499** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Nucleotide catabolism	Deoxynucleoside triphosphate triphosphohydrolase sahd-1	Q09374	sahd-1	Caenorhabditis elegans
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Derlin-1 E3 ubiquitin-protein ligase hrd-like protein 1 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-A Probable 26S proteasome regulatory subunit 4 Transitional endoplasmic reticulum ATPase homolog 2 UBX domain-containing protein 1 UV excision repair protein RAD23 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	O16368 P0CG71 P37165 P49632 P54812 P90859 Q23451 Q93561 Q9TW67 Q9TXH9	cdc-48.2 cup-2 der-1 hrdl-1 png-1 rad-23 rpt-2 ubia ubib ubl-1 ubq-1 ubq-2 ubxn-1	Caenorhabditis elegans
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase family member 2	Q18253	dpf-2	Caenorhabditis elegans
Regulation of KIT signaling	Discoidin domain-containing receptor tyrosine kinase B E3 ubiquitin-protein ligase CBL Protein kinase C-like 2 Protein kinase domain-containing protein Protein kinase domain-containing protein Sex muscle abnormal protein 5 Son of sevenless homolog	A0A1I6CMA1 P29355 P90980 Q19019 Q21046 Q95ZV7 Q9N5D3	CELE_F59F5.3 ddr-2 kin-11 kin-36 let-341 pkc-2 sem-5 sli-1 sos-1 svh-4	Caenorhabditis elegans
RAF/MAP kinase cascade	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Inactive tyrosine-protein kinase kin-32 Kringle domain-containing protein Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Ral guanine nucleotide dissociation stimulator-like 1 Rap guanine nucleotide exchange factor Ras guanyl-releasing protein 3 Ras protein let-60 Ras-GEF domain-containing family member 1B Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5 Son of sevenless homolog Spectrin alpha chain Spectrin beta chain Spectrin beta chain Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Tyrosine-protein phosphatase Lar-like Uncharacterized protein C50C3.2	A0A1I6CMA1 E0AHA7 G5EDB9 G5EDP9 G5EE56 G5EEF1 G5EFK8 G5EFW3 H2KZU7 O44191 P22981 P24348 P29355 P34367 P39745 P91823 Q10656 Q11184 Q18758 Q19770 Q19852 Q21046 Q21408 Q94125 Q95YD4 Q95ZV7 Q9BMN8 Q9N413 Q9N5D3 Q9TZA0 Q9XVQ7 W6RS10	C50C3.2/C50C3.3 CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_R05G6.10 CELE_T22A3.6 aap-1 age-1 ddr-2 egl-15 egl-17 kin-32 kin-36 kin-7 klo-1 klo-2 let-23 let-341 let-60 let-756 lin-34 mpk-1 ptp-3 pvf-1 pxf-1 ra-gef rgef-1 rgl-1 rme-2 sem-5 sma-1 sos-1 spc-1 src-1 sur-1 svh-2 svh-4 unc-70	Caenorhabditis elegans
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Kringle domain-containing protein Myoblast growth factor receptor egl-15 PIPK domain-containing protein PIPK domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Ras-related protein Rab-18 Ras-related protein ced-10 Ras-related protein rac-2 Receptor tyrosine-protein kinase let-23 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Sex muscle abnormal protein 5 Striatin N-terminal domain-containing protein Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2	A0A1I6CMA1 A0A486WY88 A9UJN4 G5EDP9 G5EE56 G5EEF1 G5EFK8 G5EGK8 H2KZU7 O01759 O18178 O44191 P24348 P29355 P91823 Q03206 Q09543 Q10656 Q11184 Q17941 Q18758 Q21046 Q94124 Q94125 Q95ZV7 Q9BL44 Q9BL73 Q9N413 Q9TZA0 Q9XTG7 Q9XVQ7	CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_T22A3.6 CELE_Y71H2AM.12 aap-1 age-1 akt-1 akt-2 cash-1 ced-10 ddr-2 egl-15 egl-17 kin-36 kin-7 klo-1 klo-2 let-23 let-756 let-92 paa-1 ppk-1 ppk-2 pptr-1 pptr-2 pvf-1 rac-1 rac-2 rme-2 sem-5 src-1 svh-2 svh-4	Caenorhabditis elegans
PI3K/AKT Signaling	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Kringle domain-containing protein Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Protein nipi-3 RICTOR_N domain-containing protein Ras-related protein Rab-18 Ras-related protein ced-10 Ras-related protein rac-2 Receptor tyrosine-protein kinase let-23 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Serine/threonine-protein kinase sgk-1 Sex muscle abnormal protein 5 Stress-activated map kinase-interacting protein 1 homolog Striatin N-terminal domain-containing protein Target of rapamycin complex subunit lst8 Target of rapamycin homolog Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 non-specific serine/threonine protein kinase	A0A1I6CMA1 A0A486WY88 G5EDP9 G5EE56 G5EED4 G5EEF1 G5EFK8 G5EFN2 H2KZU7 O44191 P24348 P29355 P91040 P91823 Q03206 Q10656 Q11184 Q17941 Q18758 Q21046 Q2PJ68 Q94124 Q94125 Q95Q95 Q95ZV7 Q9BL44 Q9N413 Q9NA80 Q9TZA0 Q9UA62 Q9XTG7 Q9XVQ7	CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_T22A3.6 CELE_W04B5.5 CELE_Y71H2AM.12 CeTor aap-1 age-1 akt-1 akt-2 cash-1 ced-10 ddr-2 egl-15 egl-17 kin-36 kin-7 klo-1 klo-2 let-23 let-363 let-756 mlst-8 nipi-3 pvf-1 rac-1 rac-2 rict-1 rme-2 sem-5 sgk-1 sinh-1 src-1 svh-2 svh-4	Caenorhabditis elegans
FLT3 Signaling	Discoidin domain-containing receptor tyrosine kinase B Forkhead box protein O Protein kinase domain-containing protein Protein kinase domain-containing protein Ras protein let-60 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Sex muscle abnormal protein 5 Son of sevenless homolog	A0A1I6CMA1 O16850 P22981 P29355 Q17941 Q21046 Q95ZV7 Q9N5D3 Q9XTG7	CELE_F59F5.3 akt-1 akt-2 daf-16 ddr-2 kin-36 let-341 let-60 lin-34 sem-5 sos-1 svh-4	Caenorhabditis elegans
Signaling by PDGF	Discoidin domain-containing receptor tyrosine kinase B Furin-like protease kpc-1 Kringle domain-containing protein Platelet-derived growth factor (PDGF) family profile domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein VWFA domain-containing protein VWFA domain-containing protein VWFA domain-containing protein VWFA domain-containing protein VWFA domain-containing protein VWFA domain-containing protein VWFA domain-containing protein	A0A1I6CMA1 G5EGU7 O01545 O17798 O76836 P91823 Q18048 Q21046 Q21394 Q95ZV7 Q9GZF5 Q9N413 Q9N5F6	C16E9.1 C18H7.1 C29A12.6 CELE_F31F7.2 CELE_F59F5.3 CELE_K09E2.1 CELE_R193.2 CELE_T19D12.4 CELE_T22A3.6 ddr-2 kin-36 kpc-1 pvf-1 svh-4	Caenorhabditis elegans
Signaling by SCF-KIT	Discoidin domain-containing receptor tyrosine kinase B Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein kinase domain-containing protein Protein kinase domain-containing protein Protein vav-1 Ras protein let-60 Ras-related protein ced-10 Sex muscle abnormal protein 5 Son of sevenless homolog	A0A1I6CMA1 G5EDP9 P22981 P29355 Q03206 Q21046 Q45FX5 Q94125 Q95ZV7 Q9N5D3	CELE_F59F5.3 aap-1 age-1 ced-10 ddr-2 kin-36 let-341 let-60 lin-34 rac-1 sem-5 sos-1 svh-4 vav-1	Caenorhabditis elegans
Synaptic adhesion-like molecules	Disks large homolog 1 GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 LITAF domain-containing protein Muscle M-line assembly protein unc-89 NMDA-type ionotropic glutamate receptor NMR-2 Reticulon-like protein Tyrosine-protein phosphatase Lar-like Tyrosine-protein phosphatase domain-containing protein	A0A1T5HUM0 G5ECY0 G5EDI2 G5EEH3 G5EGQ9 O01623 O01761 P34299 Q10914 Q17697 Q21415 Q8MXV8 Q95XL1 Q9BMN8	CELE_Y54F10BM.3 dlg-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 nmr-1 nmr-2 ptp-3 ret-1 unc-89	Caenorhabditis elegans
Neurexins and neuroligins	Disks large homolog 1 Moesin/ezrin/radixin homolog 1 Moesin/ezrin/radixin homolog 1 Neurexin-3-beta Neuroligin-1 Neuroligin-like protein glit-1 Protein lin-2 Protein shank SH3 domain-containing protein Sorbin and SH3 domain-containing protein 1 homolog	B7WN72 G5EC32 G5ECY0 G5EEG8 H2KZV9 I2HAJ6 P54936 Q18501 Q20826 Q9XTG1	C36E8.4 dlg-1 frm-1 frm-2 glit-1 lin-2 nlg-1 nrx-1 shn-1 sorb-1	Caenorhabditis elegans
Dopamine receptors	Dopamine receptor 2 Dopamine receptor 3 G-protein coupled receptors family 1 profile domain-containing protein	E7EM37 G5EGH0 Q6RYS9	dop-2 dop-2L dop-3 ser-4	Caenorhabditis elegans
Histamine receptors	Dopamine receptor 2 G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Muscarinic acetylcholine receptor gar-3	E7EM37 G5EGH0 O45601 Q9U7D5	dop-2 dop-2L gar-3 ser-4 tag-89	Caenorhabditis elegans
Serotonin receptors	Dopamine receptor 2 G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein	E7EM37 G5EGH0 P91096 Q22895 Q7JP61 Q86ME6	dop-1 dop-2 dop-2L dop-6 octr-1 ser-4 ser-7	Caenorhabditis elegans
Thyroxine biosynthesis	Dual oxidase 1 Iodotyrosine dehalogenase 1 homolog NAD(P)H oxidase (H2O2-forming) Peroxidasin homolog pxn-1 Peroxidasin homolog pxn-2 Sodium-coupled monocarboxylate transporter 2 Sodium-dependent multivitamin transporter	G5EG78 O01795 O17394 O61213 P34273 Q1ENI8 Q23616	CELE_F52H2.4 bli-3 duox-2 pxn-1 pxn-2 slc-5A12 sup-18	Caenorhabditis elegans
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Dwarfin sma-4 E3 ubiquitin-protein ligase Histone deacetylase Homeobox domain-containing protein Homeobox protein ceh-60 Mitogen-activated protein kinase mpk-1 Polyubiquitin-A Probable sodium/potassium-transporting ATPase subunit beta-3 Protein phosphatase ppm-1.A Smad protein daf-8 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta UBA domain-containing protein Ubiquitin-conjugating enzyme E2 2 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized protein T27F2.1	A0A061ACQ8 G5ECH0 G5EG81 P0CG71 P35129 P37165 P39745 P45897 P49632 Q17788 Q19775 Q21733 Q22836 Q45EK2 Q93235 Q9XUG9 Q9XUY5	CELE_T24B8.7 CELE_Y92H12A.2 T27F2.1 ceh-57 ceh-60 cem-3 daf-8 hda-3 let-70 mpk-1 nkb-1 nkb-2 nkb-3 ppm-1.A sma-4 sur-1 ubc-2 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Apoptotic execution phase	Dynamin-1-like protein drp-1 Endoplasmic reticulum transmembrane protein	G5EBI0 Q8WQC9	4D656 drp-1	Caenorhabditis elegans
ECM proteoglycans	Dystroglycan 1 Fibrinogen C-terminal domain-containing protein Fibrinogen C-terminal domain-containing protein Fibrinogen C-terminal domain-containing protein Fibronectin type-III domain-containing protein Ig-like domain-containing protein InTestinal NeureXin-like Integrin alpha ina-1 Integrin alpha pat-2 Integrin beta pat-3 Laminin G domain-containing protein SPARC Titin homolog Uncharacterized integrin beta-like protein C05D9.3	C6KRM7 G4SLH0 O45000 P34446 P34714 Q03600 Q18096 Q18705 Q22574 Q22629 Q27874 Q5ZR75 Q9GYK2 Q9XXE9	C05D9.3 C18E9.7 C49C8.5 CELE_T15B7.1 CELE_T19D12.6 CELE_Y43C5A.2 dgn-1 ina-1 itx-1 ost-1 pat-2 pat-3 rig-5 sparc ttn-1	Caenorhabditis elegans
Regulation of expression of SLITs and ROBOs	Dystroglycan 1 Slit homolog 1 protein	G5EFX6 Q22629	dgn-1 slt-1	Caenorhabditis elegans
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL EHS-1 Endophilin-A homolog Hepatocyte growth factor-regulated tyrosine kinase substrate Kringle domain-containing protein Leucine-rich repeats and immunoglobulin-like domains protein sma-10 Polyubiquitin-A Protein kinase domain-containing protein Protein sdf-9 Protein-tyrosine phosphatase Protein-tyrosine phosphatase Protein-tyrosine phosphatase Protein-tyrosine phosphatase Receptor-type tyrosine-protein phosphatase dep-1 Receptor-type tyrosine-protein phosphatase kappa SH3 domain-containing protein Sex muscle abnormal protein 5 Signal transducing adapter molecule 1 Tyrosine-protein kinase receptor svh-2 Tyrosine-protein phosphatase non-receptor type eak-6 Tyrosine-protein phosphatase Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	B1V8A0 G5EC69 G5EGA9 G5EGJ9 G5EGU2 H2KZU7 O01498 O01736 O44180 P0CG71 P29355 P37165 P49632 P91823 Q17796 Q19019 Q22852 Q6A573 Q965M2 Q9BIF4 Q9XVQ7 V6CJI9 W6RR46	CELE_F11E6.8 CELE_F20H11.4 CELE_M04G7.2 CELE_T13H5.1 CELE_T22A3.6 CELE_T28F4.3 CELE_Y71G12B.31 CELE_ZK616.65 cdap-2 dep-1 eak-5 eak-6 ehs-1 hgrs-1 pqn-19 sdf-9 sem-5 sli-1 sma-10 stam-1 svh-2 ubia ubib ubl-1 ubq-1 ubq-2 unc-57	Caenorhabditis elegans
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	E3 ubiquitin-protein ligase CBL IRS-type PTB domain-containing protein Polyubiquitin-A Protein kinase domain-containing protein Protein nipi-4 Rho-GAP domain-containing protein Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Tyrosine-protein kinase Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A4V0IL59 E6N0V1 H2KZV4 O16262 P0CG71 P37165 P49632 Q17941 Q19019 Q9N3S5 Q9XTG7	CELE_F23H11.4 CELE_Y47G6A.5 akt-1 akt-2 nipi-4 rog-1 sli-1 trk-1 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Netrin-1 signaling	E3 ubiquitin-protein ligase siah-1 Homeobox protein ceh-6 Laminin subunit beta-1 Moesin/ezrin/radixin homolog 1 Netrin receptor unc-40 Netrin receptor unc-5 Protein kinase C-like 1	G5EBK3 G5EF96 O44565 P20268 P34722 Q26261 Q965X6	ceh-6 erm-1 lam-1 siah-1 tpa-1 unc-40 unc-5	Caenorhabditis elegans
Downregulation of ERBB4 signaling	E3 ubiquitin-protein ligase wwp-1 E3 ubiquitin-protein ligase Polyubiquitin-A Receptor tyrosine-protein kinase let-23 Tyrosine protein-kinase src-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A061ACQ8 G5EE56 P0CG71 P24348 P37165 P49632 Q9N2Z7	CELE_Y92H12A.2 kin-7 let-23 src-1 ubia ubib ubl-1 ubq-1 ubq-2 wwp-1	Caenorhabditis elegans
Regulation of insulin secretion	EF-hand domain-containing protein Facilitated glucose transporter homolog Facilitated glucose transporter protein 1 Guanylate kinase/L-type calcium channel beta subunit domain-containing protein MFS domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein SH3 domain-containing protein Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent calcium channel unc-36	A0A078BQJ0 A0A3B1E663 G5EC93 O01661 O16547 O44616 O44827 O45920 P34374 Q19376 Q20734 Q21381 Q21382 Q21385 Q23535 Q23626 Q5WRR9 Q8MQA1 Q95QY6 Q9GPA2 Q9GYQ1 Q9N309 Q9NEI8 Q9U2K5 Q9XU83 Q9XVL3	C03B1.13 C35A11.4 CELE_F11D5.5 CELE_F11D5.7 CELE_F13B12.2 CELE_F48E3.2 CELE_F53H8.3 CELE_K08F9.1 CELE_K08H10.6 CELE_K09C4.1 CELE_K09C4.4 CELE_K09C4.5 CELE_Y37A1A.3 CELE_Y39B6A.41 CELE_Y39E4B.5 CELE_Y61A9LA.1 CELE_ZK829.9 R09B5.11 ccb-1 ccb-2 egl-19 fdgt-2 fgt-1 slcf-2 unc-2 unc-36 unc-72	Caenorhabditis elegans	G58161NS

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