GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **376 - 400** of **499** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
GABA synthesis, release, reuptake and degradation	Acetylcholine regulator unc-18 Glutamate decarboxylase 1 Heat shock protein hsp-1 J domain-containing protein Putative complexin-1 Rab-3-interacting molecule unc-10 Ras-related protein Rab-3 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Synaptotagmin-1 Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Vesicular GABA transporter t-SNARE protein aex-4	A5PEW5 E5QCE7 G5EBK2 G5EDB7 G5EEN8 O02495 O16000 P09446 P34351 P34579 P34693 P34815 Q19767 Q22366 Q94057 Q94986 Q95XH1 Q9GUM7	aex-4 cpx-1 dnj-14 hsp-1 hsp70a lan-2 rab-3 ric-4 snb-1 snb-2 snb-5 snb-6 snb-7 snt-1 tag-81 unc-10 unc-18 unc-25 unc-47 unc-64 vamp-7	Caenorhabditis elegans
Acetylcholine Neurotransmitter Release Cycle	Acetylcholine regulator unc-18 Choline O-acetyltransferase High-affinity choline transporter 1 Liprin-alpha Phorbol ester/diacylglycerol-binding protein unc-13 Putative complexin-1 Rab-3-interacting molecule unc-10 Ras-related protein Rab-3 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Synaptotagmin-1 Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Variant SH3 domain protein Vesicular acetylcholine transporter unc-17 t-SNARE protein aex-4	A5PEW5 G5EBK2 G5EEN8 O02228 O02495 O16000 P27715 P32756 P34351 P34693 P34711 P34815 Q19767 Q21049 Q22366 Q94057 Q94986 Q95XH1 Q9GUM7 Q9N415	aex-4 cha-1 cho-1 cpx-1 lan-2 rab-3 ric-4 rimb-1 snb-1 snb-2 snb-5 snb-6 snb-7 snt-1 syd-2 tag-168 tag-81 unc-10 unc-13 unc-17 unc-18 unc-64 vamp-7	Caenorhabditis elegans
Glutamate Neurotransmitter Release Cycle	Acetylcholine regulator unc-18 Amino acid transporter Amino acid transporter Excitatory amino acid transporter Liprin-alpha Major facilitator superfamily (MFS) profile domain-containing protein PRA1 family protein Phorbol ester/diacylglycerol-binding protein unc-13 Potential vesicular glutamate transporter vglu-3 Probable vesicular glutamate transporter eat-4 Putative complexin-1 Putative glutaminase 2 Putative glutaminase 3 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rab-3-interacting molecule unc-10 Ras-related protein Rab-3 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Synaptotagmin-1 Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Variant SH3 domain protein glutaminase t-SNARE protein aex-4	A5PEW5 G5EBK2 G5EEK1 G5EEN8 H2KZJ7 O02495 O16000 O18210 P27715 P34351 P34644 P34693 P34815 Q10046 Q10901 Q19013 Q19767 Q21049 Q21353 Q21751 Q22366 Q22682 Q93650 Q94057 Q94986 Q95XH1 Q9GUM7 Q9N415 Q9UAY8 U4PRW7	aex-4 cpx-1 eat-4 glna-1 glna-2 glna-3 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 lan-2 praf-3 rab-3 ric-4 rimb-1 snb-1 snb-2 snb-5 snb-6 snb-7 snt-1 syd-2 tag-168 tag-81 unc-10 unc-13 unc-18 unc-64 vamp-7 vglu-2 vglu-3	Caenorhabditis elegans
Platelet degranulation	Acetylcholine regulator unc-18 Actin-1 Actin-2 Actin-3 Actin-4 Alpha-actinin, sarcomeric Amyloid-beta-like protein Anaphase-promoting complex subunit 4-like WD40 domain-containing protein BMP-like protein unc-129 CYRIA/CYRIB Rac1 binding domain-containing protein Cadherin domain-containing protein Calponin-homology (CH) domain-containing protein Cathepsin F Cdc37 Hsp90 binding domain-containing protein Chitinase domain-containing protein 1 Cysteine proteinase Cysteine proteinase Dauer larva development regulatory growth factor daf-7 EF-hand domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein ELRR (Extracellular Leucine-Rich Repeat) ONly FERM domain-containing protein Fibronectin type-III domain-containing protein Fructose-bisphosphate aldolase 1 Fructose-bisphosphate aldolase 2 Hyaluronan/mRNA-binding protein domain-containing protein ILEI/PANDER domain-containing protein Ig-like and fibronectin type-III domain-containing protein 1 Ig-like and fibronectin type-III domain-containing protein 2 Ig-like and fibronectin type-III domain-containing protein C27B7.7 Ig-like domain-containing protein Ig-like domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Kringle domain-containing protein LAMP family protein lmp-1 Lipid droplet localized protein Lysosome-associated membrane glycoprotein 5 MICOS complex subunit MIC27 Mesencephalic astrocyte-derived neurotrophic factor homolog Multidrug resistance-associated protein lethal(2)03659 NTR domain-containing protein Obg-like ATPase 1 Papain family cysteine protease Pept_C1 domain-containing protein Pept_C1 domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Phosphatase and actin regulator 2 Platelet-derived growth factor (PDGF) family profile domain-containing protein Probable Hsp90 co-chaperone cdc37 Protein dbl-1 Protein lin-49 Protein unc-112 Putative metalloproteinase inhibitor tag-225 Rab27 SCAVenger receptor (CD36 family) related SCAVenger receptor (CD36 family) related SCAVenger receptor (CD36 family) related SERPIN domain-containing protein SERPIN domain-containing protein SPARC Saposin B-type domain-containing protein Saposin B-type domain-containing protein Sensory neuron membrane protein 2 Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Sulfhydryl oxidase Superoxide dismutase [Cu-Zn] Sushi domain-containing protein Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Syntaxin-binding protein 1 Tetraspanin Tetraspanin Thioredoxin domain-containing protein Torsin-like protein Torsin Torsin Tr-type G domain-containing protein Uncharacterized integrin beta-like protein C05D9.3 Uncharacterized protein C03F11.3 Uncharacterized protein R07B1.3 Vinculin	A0A1N7SYP5 A9Z1L1 G5EBM7 G5EBS5 G5EBY8 G5ECY2 G5EE40 G5EEL5 G5EFH4 G5EFK8 G5EGK1 H2KYR1 H2KZY5 H2L0F2 O01764 O02108 O16454 O17255 O17365 O17939 O18016 O18023 O44191 O44412 O45271 O45520 P0DM41 P0DM42 P10984 P10986 P19826 P34446 P34697 P34714 P34815 P46563 P54216 P91110 P91823 P91855 P91917 P92172 Q09387 Q09606 Q10651 Q11117 Q11124 Q17526 Q18096 Q18136 Q18245 Q18276 Q18279 Q18287 Q18607 Q18685 Q18740 Q18849 Q19140 Q19344 Q19625 Q19651 Q19663 Q20318 Q21154 Q21265 Q21267 Q21810 Q22174 Q23030 Q23158 Q27874 Q2AAB9 Q5F4U0 Q688B0 Q93539 Q95NU5 Q9BL26 Q9GYK0 Q9GYK2 Q9GZE9 Q9N3B0 Q9N413 Q9N4L6 Q9U2X1 Q9XTT3 Q9XVI4 Q9XVQ1 Q9XXG5 Q9XXQ7 U4PBJ9 U4PME4	C03F11.3 C05D9.3 C18E9.7 C27B7.7 C28G1.2 C32B5.13 C32B5.7 C54G4.4 CELE_F14B4.1 CELE_F15D3.4 CELE_F21C10.7 CELE_F26H9.2 CELE_F44G3.7 CELE_F47B7.2 CELE_K02E7.10 CELE_K07E8.6 CELE_R07E3.1 CELE_R07G3.8 CELE_R09F10.1 CELE_T22A3.6 CELE_Y113G7B.15 CELE_Y51A2D.8 CELE_Y71H2AM.25 CELE_Y71H2AR.2 CELE_ZK973.11 R07B1.3 act-1 act-2 act-3 act-4 aex-6 aipl-1 aldo-1 aldo-2 apl-1 atn-1 cal-5 cdc-37 cdh-10 cet-1 cfh-1 chil-10 daf-7 dbl-1 deb-1 famp-1 fln-1 igdb-1 igdb-2 iglr-1 lan-2 ldp-1 lin-49 lmp-1 lmp-2 lron-6 manf-1 moma-1 mrp-6 ola-1 ooc-5 ost-1 pat-2 pat-3 pvf-1 rab27 rme-2 scav-2 scav-3 scav-4 scav-6 slfl-5 sod-1 sparc spp-10 spp-8 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 tag-196 tag-210 tag-225 tag-329 timp-1 tln-1 tor-1 tor-2 tsp-11 tsp-7 unc-112 unc-129 unc-18 uncp-18 vig-1	Caenorhabditis elegans
Highly calcium permeable nicotinic acetylcholine receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Proton-gated ion channel subunit pbo-6	G5EDF1 P48181 P48182 Q19351 Q23022 Q23355 Q27218 Q93149 Q93329 Q9N4M3 Q9N587	acr-12 acr-2 acr-3 acr-6 acr-8 lev-1 lev-7 lev-8 lgc-3 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Proton-gated ion channel subunit pbo-6	G5EDF1 P48181 P48182 Q19351 Q23022 Q23355 Q27218 Q93149 Q93329 Q9N4M3 Q9N587	acr-12 acr-2 acr-3 acr-6 acr-8 lev-1 lev-7 lev-8 lgc-3 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Neurotransmitter receptors and postsynaptic signal transmission	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor (51.1 kD) (Acr-22) Acetylcholine receptor subunit alpha-type acr-5 Acetylcholine receptor subunit alpha-type deg-3 Acetylcholine receptor subunit alpha-type des-2 Acetylcholine-gated chloride channel subunit acc-1 Acetylcholine-gated chloride channel subunit acc-2 Acetylcholine-gated chloride channel subunit acc-3 Acetylcholine-gated ion channel acc-4 Betaine receptor acr-23 Glutamate-gated ChLoride channel Glutamate-gated chloride channel alpha Glutamate-gated chloride channel subunit beta Glutamate-gated chloride channel subunit Glycine receptor subunit beta-type 4 Ig-like domain-containing protein Ig-like domain-containing protein Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-gated ion channel 4 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Neur_chan_LBD domain-containing protein Neur_chan_LBD domain-containing protein Neur_chan_memb domain-containing protein Neur_chan_memb domain-containing protein Neurotransmitter-gated ion-channel ligand binding domain protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Probable ligand-gated ion channel 46 Serotonin-gated chloride channel mod-1	A0A1N7SYW0 A0A3P6P985 A0A4V0IK40 A0A4V0IN81 B1Q281 G5EBR3 G5ECH3 G5EDN0 G5EE87 G5EEC1 G5EEX8 G5EEZ3 G5EG88 G5EGR1 H2KML8 H2KYN9 O17041 O17274 O17402 O18228 O44452 O61216 O61519 O61520 O76554 P41849 P54244 P54245 P54246 P90876 P91985 Q09453 Q10052 Q17328 Q18812 Q21005 Q21420 Q22588 Q22741 Q6BEQ0 Q95Q97 Q95QT7 Q95Y52 Q95Y94 Q9GQ00 Q9N517 Q9NA62 Q9U358 V6CJ96 X5LVB0	acc-1 acc-2 acc-3 acc-4 acr-20 acr-21 acr-22 acr-23 acr-24 acr-4 acr-5 avr-14 avr-15 deg-3 des-2 gbr-4 ggr-1 ggr-2 ggr-3 glc-1 glc-2 glc-3 glc-4 lgc-10 lgc-11 lgc-12 lgc-30 lgc-31 lgc-32 lgc-34 lgc-39 lgc-4 lgc-40 lgc-41 lgc-42 lgc-44 lgc-45 lgc-46 lgc-47 lgc-48 lgc-49 lgc-5 lgc-50 lgc-51 lgc-52 lgc-53 lgc-54 lgc-55 lgc-56 lgc-58 lgc-6 lgc-7 lgc-8 lgc-9 mod-1	Caenorhabditis elegans
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor (51.1 kD) (Acr-22) Acetylcholine receptor subunit alpha-type acr-5 Acetylcholine receptor subunit alpha-type deg-3 Acetylcholine receptor subunit alpha-type des-2 Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Betaine receptor acr-23 Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-gated ion channel 4 Neur_chan_LBD domain-containing protein Neur_chan_memb domain-containing protein Neurotransmitter-gated ion-channel ligand binding domain protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Proton-gated ion channel subunit pbo-6	A0A3P6P985 B1Q281 G5EDF1 G5EE87 G5EG88 G5EGR1 H2KML8 O18228 O44452 O61216 O61519 O61520 O76554 P48181 P48182 P54244 P54245 P54246 Q19351 Q23022 Q23355 Q27218 Q65XS8 Q6BEQ0 Q93149 Q93329 Q95Y94 Q9N4M3 Q9N587 V6CJ96	acr-12 acr-2 acr-20 acr-21 acr-22 acr-23 acr-24 acr-25 acr-3 acr-4 acr-5 acr-6 acr-8 deg-3 des-2 lev-1 lev-7 lev-8 lgc-10 lgc-11 lgc-12 lgc-3 lgc-30 lgc-31 lgc-4 lgc-5 lgc-6 lgc-7 lgc-8 lgc-9 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Transport of vitamins, nucleosides, and related molecules	Acetyl-coenzyme A transporter 1	Q22816	CELE_T26C5.3	Caenorhabditis elegans
GRB2:SOS provides linkage to MAPK signaling for Integrins	Abnormal cell migration protein 10 FERM domain-containing protein Fibronectin type-III domain-containing protein Inactive tyrosine-protein kinase kin-32 Integrin alpha pat-2 Integrin beta pat-3 Ras-related protein Rap-1 Sex muscle abnormal protein 5 Son of sevenless homolog Tyrosine protein-kinase src-1 Uncharacterized integrin beta-like protein C05D9.3	G5EE56 G5EGK1 P29355 P34400 P34446 Q18096 Q18246 Q27874 Q95YD4 Q9GYK2 Q9N5D3	C05D9.3 C18E9.7 kin-32 let-341 mig-10 pat-2 pat-3 rap-1 sem-5 sos-1 src-1 tln-1	Caenorhabditis elegans
Integrin signaling	Abnormal cell migration protein 10 FERM domain-containing protein Fibronectin type-III domain-containing protein Inactive tyrosine-protein kinase kin-32 Integrin alpha pat-2 Integrin beta pat-3 Rap guanine nucleotide exchange factor 1 Ras guanyl-releasing protein 3 Ras-related protein Rap-1 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Tyrosine protein-kinase src-1 Tyrosine-protein kinase csk-1 Tyrosine-protein kinase Uncharacterized integrin beta-like protein C05D9.3 non-specific serine/threonine protein kinase	G5ECJ6 G5EE56 G5EGK1 P34400 P34446 P34578 Q17941 Q18096 Q18246 Q18462 Q19770 Q27874 Q95YD4 Q9GYK2 Q9UA62 Q9XTG7	C05D9.3 C18E9.7 C34F11.5 CELE_W04B5.5 akt-1 akt-2 csk-1 epac-1 kin-32 mig-10 pat-2 pat-3 rap-1 rgef-1 src-1 tln-1	Caenorhabditis elegans
WNT ligand biogenesis and trafficking	Abnormal cell lineage protein 44 GOLD domain-containing protein PX domain-containing protein Protein Wnt-1 Protein Wnt-2 Protein Wnt Protein mom-2 Protein wntless homolog Vacuolar protein sorting-associated protein 26 Vacuolar protein sorting-associated protein 29 Vacuolar protein sorting-associated protein 35	G5EG05 O01258 P34888 P34889 Q10459 Q21053 Q21336 Q27886 Q7YWX7 Q86D99 Q9XW41	cwn-1 cwn-2 egl-20 let-553 lin-44 mig-14 mom-2 mom-3 pvl-2 snx-3 tmed-1 vps-26 vps-29 vps-35 wnt-1 wnt-2	Caenorhabditis elegans
PCP/CE pathway	Abnormal cell lineage protein 44 DiSHevelled related DiSHevelled related FH2 domain-containing protein Protein Wnt-1 Protein Wnt-2 Protein mom-2 Protein mom-5 Ras-like GTP-binding protein rhoA Ras-related protein Rab-18 Ras-related protein ced-10 Ras-related protein rac-2 Segment polarity protein dishevelled homolog mig-5	A0A0K3AUI8 A0A0K3AWM6 D6VPA1 P34888 P34889 Q03206 Q10459 Q18239 Q22038 Q22227 Q27886 Q94124 Q9BL44	CELE_Y71H2AM.12 ced-10 cwn-1 cwn-2 daam-1 dsh-1 dsh-2 lin-44 mig-5 mom-2 mom-5 rac-1 rac-2 rho-1 rhoa wnt-1 wnt-2	Caenorhabditis elegans
Ca2+ pathway	Abnormal cell lineage protein 44 Beta-catenin-like protein hmp-2 Calcium/calmodulin-dependent protein kinase type II EF-hand domain-containing protein Frizzled-2 Frizzled-4 G protein gamma domain-containing protein Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma Protein Wnt-2 Protein mom-2 Protein mom-5 Protein phosphatase 2B regulatory subunit cnb-1 Protein pop-1 Ras protein let-60 Serine/threonine kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit	A0A0K3AWM6 G5ECQ2 G5ECT6 G5EDN6 G5EDV1 O44326 O62305 P17343 P22981 P34889 P51875 P54406 Q0G819 Q10459 Q10666 Q18136 Q20636 Q27886 Q9U9Y8	cal-5 cfz-2 cna-1 cnb-1 cwn-2 eat-11 gbp-2 goa-1 gpb-1 gpb-2 gpc-1 gpc-2 hmp-2 let-60 lin-17 lin-34 lin-44 lit-1 mom-2 mom-5 nlk pop-1 tax-6 unc-43 wnt-2	Caenorhabditis elegans
Acyl chain remodelling of PE	Abhydrolase domain-containing protein lid-1 C-type lectin domain-containing protein 161 C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Lysophospholipid acyltransferase 5 Lysophospholipid acyltransferase Membrane Bound O-Acyl transferase, MBOAT PNPLA domain-containing protein Phospholipase A(2) Phospholipase A2 Phospholipase A2 Phospholipase A2 phospholipase A2	G4RY15 G5EC53 H9G2W5 O01925 O02218 O16654 P34472 P91429 Q17450 Q17452 Q17790 Q18339 Q22591 Q3V5J7 Q8MXR3 Q95YD2 Q9TZ75 Q9XUL6 Q9XUL7 Q9XVE1	C03H5.4 C07E3.9 C31H1.5 C45B2.6 CELE_Y69A2AL.2 LPT-1 clec-148 clec-161 clec-178 clec-48 clec-49 clec-50 clec-51 clec-52 clec-53 clec-89 ipla-6 lid-1 mboa-3 mboa-4 mboa-6	Caenorhabditis elegans
Fatty acyl-CoA biosynthesis	ATPase morc-1 Acetyl-CoA carboxylase Delta(9)-fatty-acid desaturase fat-5 Delta(9)-fatty-acid desaturase fat-6 Delta(9)-fatty-acid desaturase fat-7 Fatty acid synthase Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Palmitoyl-protein thioesterase 1 Probable ATP-citrate synthase	G5ED44 G5EGH6 G5EGN2 H2L0M0 P53585 P91871 Q18916 Q19878 Q20390 Q23243	acly-1 acs-20 acs-22 fasn-1 fat-5 fat-6 fat-7 morc-1 pod-2 ppt-1	Caenorhabditis elegans
Serotonin Neurotransmitter Release Cycle	ATP-grasp domain-containing protein Acetylcholine regulator unc-18 Liprin-alpha Major facilitator superfamily (MFS) profile domain-containing protein Phorbol ester/diacylglycerol-binding protein unc-13 Putative complexin-1 Rab-3-interacting molecule unc-10 Ras-related protein Rab-3 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Synaptotagmin-1 Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Variant SH3 domain protein t-SNARE protein aex-4	A5PEW5 G5EBK2 G5EEN8 O02495 O16000 P27715 P34351 P34693 P34815 Q19767 Q21049 Q22366 Q8MXU3 Q94057 Q94986 Q95XH1 Q9GNP0 Q9GUM7 Q9N415	aex-4 cat-1 cpx-1 lan-2 rab-3 ric-4 rimb-1 snb-1 snb-2 snb-5 snb-6 snb-7 snn-1 snt-1 syd-2 tag-168 tag-81 unc-10 unc-13 unc-18 unc-64 vamp-7	Caenorhabditis elegans
Dopamine Neurotransmitter Release Cycle	ATP-grasp domain-containing protein Acetylcholine regulator unc-18 Liprin-alpha Major facilitator superfamily (MFS) profile domain-containing protein Phorbol ester/diacylglycerol-binding protein unc-13 Protein lin-10 Protein lin-2 Protein lin-7 homolog Putative complexin-1 Rab-3-interacting molecule unc-10 Ras-related protein Rab-3 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Synaptotagmin-1 Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Variant SH3 domain protein t-SNARE protein aex-4	A5PEW5 A5PEX5 G5EBK2 G5EEN8 O02495 O16000 O17583 P27715 P34351 P34693 P34815 P54936 Q19767 Q21049 Q22366 Q8MXU3 Q94057 Q94986 Q95XH1 Q9GNP0 Q9GUM7 Q9N415	aex-4 cat-1 cpx-1 lan-2 lin-10 lin-2 lin-7 rab-3 ric-4 rimb-1 snb-1 snb-2 snb-5 snb-6 snb-7 snn-1 snt-1 syd-2 tag-168 tag-81 unc-10 unc-13 unc-18 unc-64 vamp-7	Caenorhabditis elegans
pre-mRNA splicing	ATP-dependent RNA helicase B30.2/SPRY domain-containing protein Beta-catenin-like protein 1 N-terminal domain-containing protein CBF1-interacting co-repressor CIR N-terminal domain-containing protein CID domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein Cell division cycle 5-like protein Chromatin target of PRMT1 protein C-terminal domain-containing protein Coiled-coil domain-containing protein 12 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 G patch domain-containing protein 1 homolog Gastrulation defective protein 1 General transcription factor IIF subunit 2 Heat shock protein hsp-1 Hepatocellular carcinoma-associated antigen 59 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein K homolog Intron-binding protein aquarius K Homology domain-containing protein NF-kappa-B-activating protein C-terminal domain-containing protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear speckle splicing regulatory protein 1 homolog PHD finger-like domain-containing protein 5A PPIase cyclophilin-type domain-containing protein PWI domain-containing protein Peptidyl-prolyl cis-trans isomerase 10 Peptidyl-prolyl cis-trans isomerase 4 Peptidyl-prolyl cis-trans isomerase sig-7 Peptidyl-prolyl cis-trans isomerase Pinin/SDK/MemA protein domain-containing protein Poly(U)-binding-splicing factor rnp-6 Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor 18 Pre-mRNA-splicing factor 8 homolog Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15 Pre-mRNA-splicing factor CWC22 homolog Pre-mRNA-splicing factor CWC25 homolog Pre-mRNA-splicing factor RBM22 Pre-mRNA-splicing factor SLU7 Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor SYF1 Pre-mRNA-splicing factor syf-2 Probable ATP-dependent RNA helicase DHX35 homolog Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable U2 small nuclear ribonucleoprotein A' Probable histone deacetylase complex subunit SAP18 Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1 Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein Sm D1 Probable small nuclear ribonucleoprotein Sm D2 Probable small nuclear ribonucleoprotein-associated protein B Probable splicing factor, arginine/serine-rich 2 Probable splicing factor, arginine/serine-rich 3 Probable splicing factor, arginine/serine-rich 4 Probable splicing factor, arginine/serine-rich 6 Probable splicing factor, arginine/serine-rich 7 Proline-rich protein PRCC Protein BUD31 homolog Protein CASC3 Protein FAM32A Protein FAM50 homolog Protein isy-1 Protein mago nashi homolog Putative RNA-binding protein PTB-1a Putative RNA-binding protein R05D3.8 RNA helicase RNA helicase RNA helicase RNA polymerase Rpb4/RPC9 core domain-containing protein RNA-binding protein 5 RNA-binding protein FUS RNA-binding protein rnp-4 RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein Replication stress response regulator SDE2 SAP domain-containing protein STING ER exit protein Schlafen-like protein 2 Serrate RNA effector molecule homolog Small nuclear ribonucleoprotein Sm D3 Spliceosome RNA helicase DDX39B homolog Spliceosome-associated protein CWC15 homolog Splicing factor 45 Splicing factor Cactin Splicing factor YJU2 TPR_REGION domain-containing protein Tr-type G domain-containing protein Transcription initiation factor IIF subunit alpha U2 snRNP-associated SURP motif-containing protein U5 small nuclear ribonucleoprotein 200 kDa helicase UPF3 domain-containing protein Uncharacterized protein F37A4.2 Uncharacterized protein T27F2.1 WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein WW domain-containing protein Zinc finger protein 830 mRNA transport homolog 4	A0A3P6MY32 A9D4S6 B9WRU1 D0G911 G5EBT5 G5EBY6 G5EC45 G5ED97 G5EDE4 G5EDH3 G5EDV3 G5EEL2 G5EEW6 G5EFC4 G5EG14 O01159 O01763 O02092 O02097 O16519 O16786 O18219 O44729 O45431 O45766 O62185 O62213 P09446 P16356 P34313 P34369 P34498 P34541 P34659 P41880 P49029 P52012 P52017 P91156 P91175 P91277 P91306 P91398 P91401 P91918 Q09250 Q09252 Q09385 Q09511 Q09530 Q10013 Q10051 Q10578 Q17336 Q17348 Q17558 Q17684 Q18212 Q18265 Q18409 Q18445 Q18535 Q18691 Q18786 Q18999 Q19211 Q19614 Q19826 Q20124 Q20716 Q20875 Q20966 Q21155 Q21278 Q21322 Q21559 Q21827 Q21832 Q22037 Q22139 Q22412 Q22417 Q22836 Q23120 Q23223 Q23463 Q4W5P0 Q8MXR2 Q8MYM8 Q8WQF3 Q93338 Q93594 Q95Q06 Q95QR5 Q95XJ1 Q95Y67 Q95YF1 Q95ZQ5 Q965K2 Q965S0 Q966L5 Q966L6 Q9BIB7 Q9BIC2 Q9BKQ8 Q9BL61 Q9BLB6 Q9GR61 Q9N3C9 Q9N3S4 Q9N4G9 Q9N5K1 Q9N5K2 Q9NEW6 Q9NLD1 Q9U1Q3 Q9U1Q7 Q9U2G0 Q9U3I0 Q9XTU6 Q9XTZ2 Q9XUW5 Q9XVH6 Q9XVH9	C16C10.4 C47E8.4 CELE_K01G5.8 CELE_T23G11.4 CELE_Y18H1A.2 CELE_Y57G11A.5 CELE_Y66D12A.8 CELE_ZK616.1 E01A2.2 F37A4.2 K07C5.6 R05D3.8 R07E5.1 RBM8 T27F2.1 Y14 acin-1 aly-3 ama-1 bcas-2 bud-31 cacn-1 casc-3 cbp-20 cbp-80 ccdc-12 ccdc-55 cdc-5L cdc-5l cey-1 cey-2 cey-3 cey-4 ctnb-1 cwc-15 cyn-10 cyn-12 cyn-15 cyn-4 cyp-10 cyp-4 ddx-15 ddx-17 ddx-35 ddx-46 eftu-2 eif-4A3 emb-4 fust-1 gad-1 gtf-2F1 gtf-2F2 gtf-2f1 gtf-2f2 hel-1 hrp-1 hrp-2 hrpf-1 hrpf-2 hrpk-1 hrpl-1 hrpr-1 hrpu-1 hsp-1 hsp70a isy-1 let-504 let-858 mag-1 mog-1 mog-2 mog-3 mog-5 mog-6 mtr-4 ncbp-1 ncbp-2 pes-4 phf-5 plrg-1 pnn-1 pqbp-1.1 prcc-1 prp-17 prp-18 prp-19 prp-8 ptb-1 rbm-17 rbm-22 rbm-5 rbp-1 rnp-2 rnp-4 rnp-5 rnp-6 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 rsp-2 rsp-3 rsp-4 rsp-6 rsp-7 rsp-8 rsr-1 sacy-1 sap-1 sap-140 scaf-6 sde-2 sel-13 sig-7 smg-4 snr-1 snr-2 snr-3 snr-4 snr-5 snr-6 snr-7 snrp-200 snrp-40.1 snrp-40.2 sqd-1 srp-1 srp-2 srp-4 syf-1 syf-2 syf-3 tag-65 tofu-2 yju-2	Caenorhabditis elegans
PKR-mediated signaling	ATP-dependent RNA helicase A Cyclin-dependent kinase 1 DRBM domain-containing protein DRBM domain-containing protein DZF domain-containing protein DZF domain-containing protein Dual specificity mitogen-activated protein kinase kinase jkk-1 Dual specificity mitogen-activated protein kinase kinase mek-1 Dual specificity mitogen-activated protein kinase kinase sek-1 E3 ubiquitin-protein ligase ari-1.1 Eukaryotic translation initiation factor 2-alpha kinase pek-1 HECT domain-containing protein J domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Polyubiquitin-A Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein STE20-related kinase adapter protein strd-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Sphingosine kinase 1 Ubiquitin-conjugating enzyme E2 ubc-18 Ubiquitin-like domain-containing protein X-linked retinitis pigmentosa GTPase regulator homolog mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase	D3YT30 E9RKC7 G5EBF5 G5ECN5 G5EDF7 G5EDT6 G5EGK8 O01965 O18178 O44820 O62349 P0CG71 P34556 P91189 Q09543 Q18425 Q19192 Q20977 Q21307 Q21633 Q22307 Q58AU7 Q58AU8 Q5DX34 Q8MPS3 Q95PX0 Q9BL11 Q9NAD6 Q9TYV7 Q9XWJ9	CELE_F52C6.3 CELE_R11H6.5 CELE_T12G3.2 ari-1.1 cdk-1 dnj-7 dus-2 glo-4 herc-1 jkk-1 let-92 mek-1 mek-5 ncc-1 nck-1 paa-1 pek-1 pptr-1 rde-4 rha-1 sek-1 sek-3 sek-4 sek-5 sphk-1 sta-1 sta-2 stat-b strd-1 tag-274 ubc-18 ubia ubq-1 zfr-1	Caenorhabditis elegans
Lewis blood group biosynthesis	ATP-dependent DNA helicase Alpha-(1,3)-fucosyltransferase fut-3 DUF38 domain-containing protein F-box C protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein FTH domain-containing protein FTH domain-containing protein Hexosyltransferase L-Fucosyltransferase	A0A0K3AVC3 A0A1I6CM72 D1MN84 G5EFP5 G5EGL5 O17552 O61739 Q18255 Q19309 Q4TTB2 Q8MQG4 Q9TXT7 Q9U2D4	B0024.15 B0205.4 BE10.3 C05E4.15 C27D9.1 CEFT-4 CELE_F10E7.1 CELE_F53A2.11 CELE_F53C3.11 CELE_T05A7.11 CELE_T05A7.13 CELE_Y47D3A.1 fut-3 pha-1 pha1	Caenorhabditis elegans	G39211DH G81971FM G90387AM G98173LG
Reactions specific to the complex N-glycan synthesis pathway	ATP-dependent DNA helicase Alpha-(1,3)-fucosyltransferase fut-3 Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-mannosidase Alpha-mannosidase DUF38 domain-containing protein F-box C protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein FTH domain-containing protein FTH domain-containing protein Putative alpha-L-fucosidase	A0A0K3AVC3 A0A1I6CM72 D1MN84 G5EFE7 G5EFP5 G5EGL5 O01574 O17552 O17560 P49713 Q18255 Q19309 Q2PJ74 Q4TTB2 Q9TXT7 Q9U2D4	BE10.3 C05E4.15 C27D9.1 CEFT-4 CELE_F10E7.1 CELE_F53A2.11 CELE_F53C3.11 CELE_T05A7.11 CELE_T05A7.13 CELE_Y47D3A.1 W03G11.3 aman-2 aman-3 fut-3 fut-8 gly-20 pha-1 pha1	Caenorhabditis elegans	G70323CJ G82576YO
Glycolysis	ATP-dependent 6-phosphofructokinase 1 ATP-dependent 6-phosphofructokinase 2 Enolase Fructose-bisphosphate aldolase 1 Fructose-bisphosphate aldolase 2 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase 1 Glyceraldehyde-3-phosphate dehydrogenase 2 Glyceraldehyde-3-phosphate dehydrogenase 3 Glyceraldehyde-3-phosphate dehydrogenase 4 Phosphoglucomutase-2 Phosphotransferase Phosphotransferase Phosphotransferase Probable ADP-dependent glucokinase Probable glucosamine-6-phosphate isomerase Probable phosphoglycerate kinase Pyruvate kinase Pyruvate kinase Triosephosphate isomerase	B7WNA0 O45934 P04970 P17329 P17330 P17331 P46563 P54216 P91427 Q10657 Q19440 Q23539 Q27483 Q27527 Q7K707 Q86S40 Q9N4A5 Q9TZL8 Q9XU15 Q9XVJ2	C50D2.7 CELE_Y43F4B.5 T03F6.3 aldo-1 aldo-2 enol-1 gpd-1 gpd-2 gpd-3 gpd-4 gpi-1 hxk-1 hxk-2 hxk-3 pfk-1.1 pfk-1.2 pgk-1 pyk-1 pyk-2 tpi-1	Caenorhabditis elegans	G58161NS
Nicotinamide salvaging	ATP-dependent (S)-NAD(P)H-hydrate dehydratase NAD(P)H-hydrate epimerase NAD-capped RNA hydrolase ndx-9 Nicotinamide N-methyltransferase Nicotinate phosphoribosyltransferase Organic cation transporter 1 Sodium-dependent multivitamin transporter	P32740 P34254 Q19427 Q23616 Q95XX1 Q9U539 Q9XW15	R107.2 Y18D10A.3 anmt-1 ndx-9 nprt-1 oct-1 slc-5A12	Caenorhabditis elegans
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	AP complex subunit beta AP complex subunit sigma AP-2 complex subunit alpha AP-2 complex subunit mu Clathrin light chain Frizzled-2 Probable clathrin heavy chain 1 Protein Wnt-2 Protein mom-5 Tyrosine-protein kinase receptor cam-1	A0A0K3AWM6 G5ECQ2 G5EGK5 P34574 P34889 P35603 P90961 Q19123 Q22601 Q9N4F3	ap50 apa-2 apb-1 aps-2 cam-1 cfz-2 chc-1 clic-1 cwn-2 dpy-23 kin-8 mom-5 wnt-2	Caenorhabditis elegans

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