GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **401 - 425** of **499** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
RAB geranylgeranylation	GTP-binding protein Rhes Geranylgeranyl transferase type-2 subunit alpha Probable geranylgeranyl transferase type-2 subunit beta RAB family RAB family RAB family RAB family Rab proteins geranylgeranyltransferase component A 1 Rab27 Rab8 Ras and EF-hand domain-containing protein homolog Ras-related protein Rab-10 Ras-related protein Rab-10 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-21 Ras-related protein Rab-2 Ras-related protein Rab-2A Ras-related protein Rab-2A Ras-related protein Rab-30 Ras-related protein Rab-33 Ras-related protein Rab-35 Ras-related protein Rab-3 Ras-related protein Rab-7a Ras-related protein Rab Ras-related protein rab-11.1 Ras-related protein rab-39 Ras-related protein rab-6.1 Ras-related protein rab-6.2 small monomeric GTPase	A0A2C9C2Y0 G5EBF0 G5EBS5 G5EFA6 G5EFC1 O01803 O17788 O17789 P34213 P41992 P91857 Q18969 Q1ZXR4 Q1ZXV0 Q20365 Q21137 Q22045 Q22782 Q22908 Q23146 Q8MXS1 Q93874 Q94148 Q94986 Q9BKQ5 Q9TYY0 Q9U1W9 Q9U2C3 Q9UAQ6 Q9XWZ3	CELE_M57.2 CELE_ZK669.5 aex-6 ggtb-1 glo-1 rab-1 rab-10 rab-11.1 rab-11.2 rab-14 rab-18 rab-19 rab-21 rab-3 rab-30 rab-33 rab-35 rab-37 rab-39 rab-5 rab-6.1 rab-6.2 rab-7 rab-8 rab27 rab8 rabr-1 rabr-3 rabr-4 rep-1 rsef-1 tag-312 unc-108	Caenorhabditis elegans
GABA receptor activation	Gamma-aminobutyric acid receptor exp-1 Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Ligand-Gated ion Channel Ligand-Gated ion Channel Neurotransmitter-gated ion-channel ligand-binding domain-containing protein	A0A3P6NNS2 G5ECD3 G5ECJ0 G5ECN1 O18276 Q6BET0 Q7YTP9 Q9U2E2	exp-1 gab-1 lgc-35 lgc-36 lgc-37 lgc-38 lgc-43 unc-49 unc-49B	Caenorhabditis elegans
GABA B receptor activation	Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2	G5ECB2 H2L0Q3	gbb-1 gbb-2	Caenorhabditis elegans
Nuclear signaling by ERBB4	Gamma-secretase subunit aph-1 Gamma-secretase subunit pen-2 NAD(P)-binding protein Nicastrin Presenilin sel-12 Protein kinase domain-containing protein Receptor tyrosine-protein kinase let-23 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Tyrosine protein-kinase src-1 Yes-associated protein homolog 1	D3YT30 G5EE56 O45876 P24348 P52166 Q19062 Q19404 Q20977 Q23316 Q9NAD6 Q9U357	CELE_T12G3.2 aph-1 aph-2 dhs-7 kin-7 let-23 pen-1 pen-2 sel-12 src-1 sta-1 sta-2 stat-b yap-1	Caenorhabditis elegans
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Geranylgeranyl transferase type-2 subunit alpha Probable geranylgeranyl transferase type-2 subunit beta Rab proteins geranylgeranyltransferase component A 1	P41992 Q9BKQ5 Q9TYY0	CELE_M57.2 ggtb-1 rep-1	Caenorhabditis elegans
Prednisone ADME	Glucuronosyltransferase NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein SERPIN domain-containing protein SERPIN domain-containing protein Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein	A9Z1L1 G5ECY2 G5EE40 G5EFH4 O17365 O45520 P91020 P91997 P91998 Q17568 Q18287 Q18903 Q19082 Q19651 Q21274 Q22352 Q23320 Q9NAI5 Q9U2J5 Q9XVQ1	C01G5.5 C07D8.6 C28G1.2 C56G3.2 CELE_F15D3.4 CELE_F44G3.7 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_ZC443.1 exc-15 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 ugt-57	Caenorhabditis elegans
Nicotinate metabolism	Glutamine-dependent NAD(+) synthetase NAD kinase 2, mitochondrial Nicotinamide-nucleotide adenylyltransferase Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2	P91851 Q9XXI5 Q9XXK6 Q9XXM2	nadk-2 nmat-1 nmat-2 qns-1	Caenorhabditis elegans
Glutathione conjugation	Glutathione S-Transferase Glutathione S-transferase P Glutathione S-transferase omega Glutathione S-transferase omega Glutathione S-transferase Glutathione s-transferase kappa 2 Glutathione transferase omega-1 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Probable glutathione transferase omega-2 Probable maleylacetoacetate isomerase S-formylglutathione hydrolase	D7SFI3 G5EF86 O17234 O45352 P10299 P34277 P34345 P91020 P91997 P91998 Q17568 Q18903 Q18938 Q18973 Q21274 Q21945 Q22352 Q23320 Q9NAI5 Q9U2J5	C01G5.5 C02D5.4 C07D8.6 C56G3.2 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_Y48G10A.1 CELE_ZC443.1 exc-15 gst-1 gst-11 gst-42 gst-44 gstk-2 gsto-1 gsto-2 gsto-3	Caenorhabditis elegans
Signaling by ROBO receptors	GlyPicaN LONg Protein sax-3 Slit homolog 1 protein Thioredoxin domain-containing protein	G5EBF1 G5ECV3 G5EFX6 G5EGU4 Q18530	C03H12.1 gpn-1 lon-2 sax-3 slt-1	Caenorhabditis elegans
Sema4D induced cell migration and growth-cone collapse	Guanine nucleotide exchange factor Plexin-2 Ras-like GTP-binding protein rhoA Receptor tyrosine-protein kinase let-23 Rho-associated protein kinase let-502 Sema domain-containing protein Semaphorin-1A Semaphorin-2A	G5EFE1 O45657 P24348 P92199 Q17330 Q22038 Q95XP4 Q9TYS4	kin-7 let-23 let-502 mab-20 plx-2 rhgf-1 rho-1 rhoa sema-1a smp-1 smp-2	Caenorhabditis elegans
Phase 2 - plateau phase	Guanylate kinase/L-type calcium channel beta subunit domain-containing protein SH3 domain-containing protein STarGazin (Mammalian calcium channel) homolog STarGazin (Mammalian calcium channel) homolog Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent calcium channel unc-36	A0A078BQJ0 G5EBI8 G5EDT2 O01661 P34374 Q8MQA1	STG-1 ccb-1 ccb-2 egl-19 stg-1 stg-2 unc-36 unc-72	Caenorhabditis elegans
Phase 0 - rapid depolarisation	Guanylate kinase/L-type calcium channel beta subunit domain-containing protein SH3 domain-containing protein STarGazin (Mammalian calcium channel) homolog STarGazin (Mammalian calcium channel) homolog Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent calcium channel unc-36	A0A078BQJ0 G5EBI8 G5EDT2 O01661 P34374 Q8MQA1	STG-1 ccb-1 ccb-2 egl-19 stg-1 stg-2 unc-36 unc-72	Caenorhabditis elegans
Drug-mediated inhibition of ERBB2 signaling	Heat shock protein 90 Probable Hsp90 co-chaperone cdc37 Receptor tyrosine-protein kinase let-23	O02108 P24348 Q18688	cdc-37 daf-21 kin-7 let-23	Caenorhabditis elegans
Myogenesis	Helix-loop-helix protein hlh-2 MEF2 transcription factor homolog Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 Myoblast determination protein 1 homolog Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein	G5EEG9 G5EFV1 O44514 P22980 P91267 Q17446 Q8MXI4 Q93344 Q9U325 Q9U3L3 Q9XX60 Q9XXC0	C49C3.10 CELE_F21F3.2 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 CeMef-2 gska-3 gskl-2 hlh-1 hlh-2 mef-2 pmk-1 pmk-2 pmk-3	Caenorhabditis elegans
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	High mobility group protein hmg-12 Histone H1.3 Intermediate filament protein ifa-1 Intermediate filament protein ifa-2 Intermediate filament protein ifa-3 Intermediate filament protein ifa-4 Intermediate filament protein ifb-1 Intermediate filament protein ifb-2 Intermediate filament protein ifc-1 Intermediate filament protein ifc-2 Intermediate filament protein ifd-1 Intermediate filament protein ifd-2 Intermediate filament protein ifp-1 Lamin-1 Probable histone chaperone asf-1 Protein HIRA Pry-1 Interacting and CABIN1 Domain containing	A0A0K3AUI7 G5EDQ2 O02365 O45168 P90900 P90901 Q09501 Q09589 Q19286 Q19289 Q19326 Q19743 Q19782 Q21065 Q21067 Q21443 Q86DC6	asf-1 hil-3 hira-1 hmg-12 hmg-I-beta ifa-1 ifa-2 ifa-3 ifa-4 ifb-1 ifb-2 ifc-1 ifc-2 ifd-1 ifd-2 ifp-1 lam-1 lmn-1 mua-6 picd-1 unc-85	Caenorhabditis elegans
Phase 4 - resting membrane potential	IRK_C domain-containing protein Inward rectifier potassium channel irk-1 Inward rectifier potassium channel irk-1 Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein TWiK family of potassium channels protein 18 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Uncharacterized protein B0310.1	A0A1C3NSK2 A0A1C3NSN6 A1EHR5 F5GUD1 G5EBQ2 G5ECW6 G5EG92 G5EGD4 H2KZ66 O17185 O45422 O45891 O45894 P52192 Q10937 Q18120 Q21467 Q22042 Q22043 Q23297 Q65XY3 Q6BES3 Q6EUT8 Q9BL31 Q9NEV3 Q9XTV6 U4PFA8	B0310.1 irk-1 irk-2 irk-3 irk-4 sup-9 twk-1 twk-11 twk-14 twk-18 twk-20 twk-21 twk-22 twk-24 twk-25 twk-26 twk-31 twk-33 twk-34 twk-35 twk-36 twk-39 twk-42 twk-44 twk-45 twk-46 twk-49 twk-8	Caenorhabditis elegans
Nectin/Necl trans heterodimerization	Ig-like domain-containing protein	A7LPD6	igcm-3	Caenorhabditis elegans
Laminin interactions	Ig-like domain-containing protein Integrin alpha ina-1 Integrin beta pat-3 Multiple epidermal growth factor-like domains protein 6 Titin homolog Uncharacterized integrin beta-like protein C05D9.3	C6KRM7 G4SLH0 G5EFX3 Q03600 Q27874 Q9GYK2	C05D9.3 CELE_Y64G10A.7 ina-1 pat-3 rig-5 ttn-1	Caenorhabditis elegans
Non-integrin membrane-ECM interactions	Ig-like domain-containing protein Platelet-derived growth factor (PDGF) family profile domain-containing protein Probable 5-hydroxyisourate hydrolase R09H10.3 Probable 5-hydroxyisourate hydrolase ZK697.8 Protein kinase domain-containing protein Protein let-756 Titin homolog	C6KRM7 G4SLH0 O44578 Q10915 Q11184 Q21882 Q9N413	B0252.1 R09H10.3 ZK697.8 let-756 pvf-1 rig-5 ttn-1	Caenorhabditis elegans
MET activates PTK2 signaling	Inactive tyrosine-protein kinase kin-32 Integrin alpha ina-1 Integrin alpha pat-2 Kringle domain-containing protein Multiple epidermal growth factor-like domains protein 6 Protein kinase domain-containing protein Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Uncharacterized integrin beta-like protein C05D9.3	G5EE56 G5EFX3 H2KZU7 P34446 P91823 Q03600 Q95YD4 Q9GYK2 Q9XVQ7	C05D9.3 CELE_F11E6.8 CELE_T22A3.6 CELE_Y64G10A.7 ina-1 kin-32 pat-2 src-1 svh-2	Caenorhabditis elegans
NCAM signaling for neurite out-growth	Inactive tyrosine-protein kinase kin-32 Mitogen-activated protein kinase mpk-1 Putative ribosomal protein S6 kinase alpha-2 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog Spectrin alpha chain Spectrin beta chain Spectrin beta chain Tyrosine protein-kinase src-1 Tyrosine-protein phosphatase Lar-like Uncharacterized protein C50C3.2	E0AHA7 G5EE56 G5EFW3 P22981 P29355 P34367 P39745 Q18846 Q21408 Q95YD4 Q9BMN8 Q9N5D3	C50C3.2/C50C3.3 kin-32 let-341 let-60 lin-34 mpk-1 ptp-3 rskn-2 sem-5 sma-1 sos-1 spc-1 src-1 sur-1 unc-70	Caenorhabditis elegans
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Inositol 1,4,5-trisphosphate receptor itr-1 Stromal interaction molecule 1 Transient receptor ion channel domain-containing protein	G5EF60 Q8I6Y9 Q9Y0A1	dec-4 itr-1 lfe-1 stim-1 trp-2	Caenorhabditis elegans
Insulin receptor recycling	Insulin-like receptor Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit S1 V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q22494 Q23680 Q95X44 Q95YD5 Q968Y9 Q9N5A0 Q9TYW1 Q9XW92 Q9XXU9	daf-2 fus-1 rdy-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-19 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
Cross-presentation of particulate exogenous antigens (phagosomes)	Integrin alpha pat-2 Integrin beta pat-3 SCAVenger receptor (CD36 family) related SCAVenger receptor (CD36 family) related SCAVenger receptor (CD36 family) related Sensory neuron membrane protein 2 Uncharacterized integrin beta-like protein C05D9.3 Uncharacterized protein C03F11.3 Uncharacterized protein R07B1.3	G5EBM7 P34446 Q09606 Q11124 Q19140 Q19344 Q27874 Q9GYK2 Q9XTT3	C03F11.3 C05D9.3 R07B1.3 pat-2 pat-3 scav-2 scav-3 scav-4 scav-6	Caenorhabditis elegans
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Integrin alpha pat-2 Uncharacterized integrin beta-like protein C05D9.3	P34446 Q9GYK2	C05D9.3 pat-2	Caenorhabditis elegans

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