GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **499** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	FERM domain-containing protein Moesin/ezrin/radixin homolog 1 PIPK domain-containing protein Sema domain-containing protein Sema domain-containing protein Semaphorin-1A Semaphorin-2A Tyrosine protein-kinase src-1	G5EE56 G5EGK1 O01759 O17905 Q17330 Q95XP4 Q9TYS4 U4PRY7	frm-3 mab-20 plx-1 ppk-1 sema-1a smp-1 smp-2 src-1 tln-1	Caenorhabditis elegans
SDK interactions	Protein sidekick homolog	Q9N3X8	rig-4	Caenorhabditis elegans
SCF(Skp2)-mediated degradation of p27/p21	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 BRCT domain-containing protein Cullin-1 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor Cyclin-dependent kinases regulatory subunit F-box domain-containing protein G1/S-specific cyclin-E G2/mitotic-specific cyclin-A1 GNAT family N-acetyltransferase MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Skp1-related protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A131MD44 G5ECU1 G5EEJ2 O01501 O16368 O17071 O17586 O44156 O61742 O61792 O61847 O62102 O76371 O76577 P0CG71 P34638 P37165 P46502 P49632 P90868 P91477 Q04908 Q09397 Q10920 Q17389 Q17868 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q22319 Q23237 Q23449 Q27488 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9XTT9 Q9XUV0	CELE_F35G12.12 CELE_T07F10.5 CELE_T24A6.1 cdk-2 cki-2 cks-1 cul-1 cya-1 cye-1 dom-6 lin-19 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 skpt-1 skr-1 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Role of phospholipids in phagocytosis	PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein Phospholipase Probable phospholipase D F09G2.8 Protein kinase C-like 1 Protein kinase C-like 1B phospholipase A2	G5EDU3 H2KZ05 O17405 P34722 P34885 Q19056 Q8I4C7 Q95YD2	C45B2.6 CELE_E04F6.4 CELE_T05C3.6 CELE_Y51A2D.13 F09G2.8 PLD kin-13 pkc-1 pld-1 tpa-1 ttx-4	Caenorhabditis elegans
Reuptake of GABA	Transporter	G5EF43	snf-11	Caenorhabditis elegans
Retinoid metabolism and transport	Beta,beta-carotene 9',10'-oxygenase Beta,beta-carotene 9',10'-oxygenase Carotenoid oxygenase Fatty acid-binding protein homolog 5 Fatty acid-binding protein homolog 6 Fatty acid-binding protein homolog 7 Fatty acid-binding protein homolog 8 LiPocalin-Related protein Lipase_GDSL domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Probable 5-hydroxyisourate hydrolase R09H10.3 Probable 5-hydroxyisourate hydrolase ZK697.8	G5EEB8 H2L060 O01812 O01814 O02323 O02324 O44578 P91020 P91997 P91998 Q17568 Q18903 Q21274 Q21882 Q22352 Q23320 Q9N2Z4 Q9NAI5 Q9TXT9 Q9U2E4 Q9U2J5	C01G5.5 C07D8.6 C56G3.2 CELE_F49E10.2 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_Y65B4BR.1 CELE_ZC443.1 R09H10.3 ZK697.8 bcmo-1 bcmo-2 exc-15 lbp-5 lbp-6 lbp-7 lbp-8 lpr-2	Caenorhabditis elegans
Response to elevated platelet cytosolic Ca2+	Protein kinase C-like 2	P90980	kin-11 pkc-2	Caenorhabditis elegans
Regulation of ornithine decarboxylase (ODC)	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antizyme inhibitor 1 MPN domain-containing protein Ornithine decarboxylase antizyme Ornithine decarboxylase PCI domain-containing protein Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5	O01579 O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P41931 P46502 P90868 P91477 Q04908 Q10920 Q17971 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q27488 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9NHZ6 Q9XTT9 Q9XUV0	C14C10.5 CELE_F35G12.12 CELE_F53F10.2 oaz-1 odc-1 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6	Caenorhabditis elegans
Regulation of localization of FOXO transcription factors	14-3-3-like protein 1 14-3-3-like protein 2 Forkhead box protein O Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2	O16850 P41932 Q17941 Q20655 Q9XTG7	akt-1 akt-2 daf-16 ftt-1 ftt-2 par-5	Caenorhabditis elegans
Regulation of insulin secretion	EF-hand domain-containing protein Facilitated glucose transporter homolog Facilitated glucose transporter protein 1 Guanylate kinase/L-type calcium channel beta subunit domain-containing protein MFS domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein SH3 domain-containing protein Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent calcium channel unc-36	A0A078BQJ0 A0A3B1E663 G5EC93 O01661 O16547 O44616 O44827 O45920 P34374 Q19376 Q20734 Q21381 Q21382 Q21385 Q23535 Q23626 Q5WRR9 Q8MQA1 Q95QY6 Q9GPA2 Q9GYQ1 Q9N309 Q9NEI8 Q9U2K5 Q9XU83 Q9XVL3	C03B1.13 C35A11.4 CELE_F11D5.5 CELE_F11D5.7 CELE_F13B12.2 CELE_F48E3.2 CELE_F53H8.3 CELE_K08F9.1 CELE_K08H10.6 CELE_K09C4.1 CELE_K09C4.4 CELE_K09C4.5 CELE_Y37A1A.3 CELE_Y39B6A.41 CELE_Y39E4B.5 CELE_Y61A9LA.1 CELE_ZK829.9 R09B5.11 ccb-1 ccb-2 egl-19 fdgt-2 fgt-1 slcf-2 unc-2 unc-36 unc-72	Caenorhabditis elegans	G58161NS
Regulation of expression of SLITs and ROBOs	Dystroglycan 1 Slit homolog 1 protein	G5EFX6 Q22629	dgn-1 slt-1	Caenorhabditis elegans
Regulation of actin dynamics for phagocytic cup formation	Actin-1 Actin-2 Actin-3 Actin-4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog FERM domain-containing protein Inactive tyrosine-protein kinase kin-32 Membrane-associated protein gex-3 Mitogen-activated protein kinase mpk-1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Probable actin-related protein 2/3 complex subunit 2 Probable actin-related protein 2/3 complex subunit 3 Probable actin-related protein 2/3 complex subunit 4 Protein BRICK1 Ras-related protein ced-10 SH3 domain-containing protein SPIN90/Ldb17 leucine-rich domain-containing protein Serine/threonine-protein kinase pak-1 Sex muscle abnormal protein 5 Tyrosine-protein kinase abl-1 WASH complex subunit homolog 1 Wiskott-Aldrich syndrome protein family member	A0A3P6PCS5 A5Z2X2 H2KYX3 O18195 O44518 O61861 P03949 P0DM41 P0DM42 P10984 P10986 P29355 P39745 P53489 P55163 P58798 Q03206 Q05062 Q10929 Q17850 Q8WTM6 Q95PX0 Q95YD4 Q9N372 Q9N4I0 Q9XVK6 Q9XWV3	CELE_Y55F3AM.5 CELE_Y57G11C.1147 abi-1 abl-1 act-1 act-2 act-3 act-4 arp-2 arx-1 arx-2 arx-3 arx-4 arx-5 arx-6 arx-7 cdc-42 ced-10 ddl-2 gex-2 gex-3 kin-32 mpk-1 nck-1 nfm-1 pak-1 rac-1 sem-5 sur-1 wve-1	Caenorhabditis elegans
Regulation of TP53 Activity through Acetylation	Chromatin modification-related protein MEAF6 Chromodomain-helicase-DNA-binding protein 3 homolog DIOX_N domain-containing protein Histone deacetylase 1 Histone deacetylase ING family member lsy-13 Probable histone-binding protein lin-53 Probable histone-binding protein rba-1 Protein let-418 Protein lin-49 RING-type E3 ubiquitin transferase RING-type domain-containing protein RING-type domain-containing protein Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Transcription factor dcp-66 histone acetyltransferase	A3QMD7 G5EBZ4 G5ECH0 G5ED20 G5ED89 H2L0K3 O17695 O61907 P90916 P90917 Q17941 Q19818 Q20318 Q22516 Q8WQC3 Q95ZX6 Q9XTG7	B0025.4 akt-1 akt-2 chd-3 dcp-66 evl-11 hda-1 hda-3 let-418 lin-40 lin-49 lin-53 lsy-13 mys-4 nhl-2 nhl-3 rba-1 rba-2 tam-1	Caenorhabditis elegans
Regulation of TLR by endogenous ligand	BPI1 domain-containing protein BPI2 domain-containing protein BPI2 domain-containing protein BPI2 domain-containing protein High mobility group protein 1.2 Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Nose resistant to fluoxetine protein 5 Uncharacterized protein T19C3.5	A8WFJ7 H9G2Z8 O17768 Q09390 Q10011 Q17654 Q17738 Q18869 Q20380 Q23365 Q93796	C05C9.1 C06E8.5 C06G1.1 C55C3.1 CELE_F01G10.10 CELE_F10D11.6 CELE_F44A2.3 CELE_ZC513.2 T19C3.5 hmg-1.2 nrf-5	Caenorhabditis elegans
Regulation of RUNX3 expression and activity	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 BMP-like protein unc-129 Core-binding factor subunit beta homolog bro-1 Dauer larva development regulatory growth factor daf-7 MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Protein dbl-1 Runt-related transcription factor rnt-1 Tyrosine protein-kinase src-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	G5EBY8 G5EE56 G5EEL5 G5EFQ5 O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P37165 P46502 P49632 P90868 P91477 P92172 Q04908 Q10920 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q27488 Q95005 Q95008 Q95PZ7 Q95ZL9 Q966I8 Q9GZH5 Q9N599 Q9XTT9 Q9XUV0	CELE_F35G12.12 bro-1 cet-1 daf-7 dbl-1 mab-2 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rnt-1 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 run-1 src-1 ubia ubib ubl-1 ubq-1 ubq-2 unc-129	Caenorhabditis elegans
Regulation of RUNX2 expression and activity	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase CHIP F-box domain-containing protein MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 RING-box protein 1 Runt-related transcription factor rnt-1 Skp1-related protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	G5ECU1 G5ECY6 G5EFQ5 O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P37165 P46502 P49632 P90868 P91477 Q04908 Q09397 Q10920 Q17389 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q23457 Q27488 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9XTT9 Q9XUV0	1G758 CELE_F35G12.12 chn-1 cul-1 lin-19 mab-2 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rbx-1 rnt-1 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 run-1 skpt-1 skr-1 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Regulation of RUNX1 Expression and Activity	Core-binding factor subunit beta homolog bro-1 G1/S-specific cyclin-D RING-type E3 ubiquitin transferase RING-type domain-containing protein RING-type domain-containing protein Runt-related transcription factor rnt-1	G5ED20 G5EFQ5 H2L0K3 Q19818 Q95ZL9 Q9U2M5	bro-1 cyd-1 mab-2 nhl-2 nhl-3 rnt-1 run-1 tam-1	Caenorhabditis elegans
Regulation of PTEN stability and activity	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Casein kinase II subunit alpha Casein kinase II subunit beta E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase makorin E3 ubiquitin-protein ligase wwp-1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase MPN domain-containing protein PCI domain-containing protein Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 RING-type domain-containing protein Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Tyrosine protein-kinase src-2 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein ubiquitinyl hydrolase 1	A0A061ACQ8 G5ECY6 G5EE01 O16368 O17071 O17586 O44156 O45539 O61742 O61792 O62102 O76371 O76577 P0CG71 P18334 P28548 P37165 P46502 P49632 P90868 P91477 Q04908 Q10920 Q17941 Q17971 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q27488 Q7JLI8 Q8WQB0 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N2Z7 Q9N373 Q9N3T6 Q9N599 Q9XTG7 Q9XTT9 Q9XUV0	1G758 C14C10.5 CELE_F35G12.12 CELE_Y105E8A.14 CELE_Y47G6A.14 CELE_Y92H12A.2 akt-1 akt-2 chn-1 daf-18 duo-1 kin-10 kin-22 kin-3 kin-5 lep-2 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 src-2 ubia ubib ubl-1 ubq-1 ubq-2 wwp-1	Caenorhabditis elegans
Regulation of PTEN localization	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 Polyubiquitin-A RING-type E3 ubiquitin transferase RING-type domain-containing protein RING-type domain-containing protein Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	G5ED20 G5EE01 H2L0K3 P0CG71 P37165 P49632 Q19818 Q7JKC3	daf-18 math-33 nhl-2 nhl-3 tam-1 ubia ubib ubl-1 ubq-1 ubq-2 usp-7	Caenorhabditis elegans
Regulation of PTEN gene transcription	DAF-15 GTP-binding protein Rheb homolog 1 GTP-binding protein Histone-lysine N-methyltransferase mes-2 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Polycomb protein mes-6 Probable histone-binding protein lin-53 Probable histone-binding protein rba-1 Ragulator complex protein LAMTOR2 homolog Ras-related GTP-binding protein C Repressor of RNA polymerase III transcription MAF1 Sodium-coupled neutral amino acid transporter 9 homolog Target of rapamycin complex subunit lst8 Target of rapamycin homolog Zinc finger protein egl-43	G5EGB3 O17268 O17514 P34443 P90916 P90917 P91040 Q19425 Q22024 Q22743 Q68TI8 Q8WQG5 Q95Q95 Q9GYS1 Q9N2U6 Q9TZN2	CeTor F13H10.3 daf-15 egl-43 let-363 lin-53 lmtr-2 lmtr-3 lmtr-5 mafr-1 mes-2 mes-6 mlst-8 raga-1 ragc-1 rba-1 rba-2 rheb-1	Caenorhabditis elegans
Regulation of KIT signaling	Discoidin domain-containing receptor tyrosine kinase B E3 ubiquitin-protein ligase CBL Protein kinase C-like 2 Protein kinase domain-containing protein Protein kinase domain-containing protein Sex muscle abnormal protein 5 Son of sevenless homolog	A0A1I6CMA1 P29355 P90980 Q19019 Q21046 Q95ZV7 Q9N5D3	CELE_F59F5.3 ddr-2 kin-11 kin-36 let-341 pkc-2 sem-5 sli-1 sos-1 svh-4	Caenorhabditis elegans
Regulation of IGF Activity by IGFBP	Amyloid-beta-like protein Anoctamin Apolipoprotein L, 1 Apolipoprotein L3-like BMP-like protein unc-129 Calumenin-like protein Cystatin cpi-2 DUF19 domain-containing protein Dauer larva development regulatory growth factor daf-7 Disintegrin and metalloproteinase domain-containing protein 10 homolog EGL-17 Endoplasmin homolog Extracellular serine/threonine protein kinase CeFam20 Fibronectin type-III domain-containing protein Galectin domain-containing protein Glucosidase 2 subunit beta J domain-containing protein Multiple epidermal growth factor-like domains protein 6 NTR domain-containing protein NUCleoBindin homolog Nidogen PNPLA domain-containing protein PNPLA domain-containing protein Patanin-like phospholipase domain-containing protein atgl-1 Probable syndecan Protein dbl-1 Protein disulfide-isomerase 1 Protein disulfide-isomerase 2 Protein disulfide-isomerase A6 homolog Putative alpha-L-fucosidase Putative metalloproteinase inhibitor tag-225 SERPIN domain-containing protein SERPIN domain-containing protein SPARC Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Sulfhydryl oxidase Thioredoxin domain-containing protein Transmembrane protein 132 homolog VWFA domain-containing protein	A9Z1L1 G5EBH7 G5EBY8 G5EC87 G5ECM9 G5ECY2 G5EE40 G5EEF1 G5EEL5 G5EFD9 G5EFH4 G5EFX3 H2FLL2 H2KZY5 H2L2L3 O17365 O45520 P34714 P49713 P50605 P91189 P92172 Q09EE8 Q10651 Q11067 Q11186 Q17770 Q17967 Q18048 Q18096 Q18287 Q18948 Q19651 Q20684 Q21265 Q21267 Q22235 Q8MQ51 Q8WQF7 Q8WQF8 Q93791 Q9BL47 Q9N5Z7 Q9XTW2 Q9XVQ1	B0524.2 C16E9.1 C18E9.7 C28G1.2 CELE_D1054.1 CELE_F07F6.7 CELE_F07F6.8 CELE_F15D3.4 CELE_F44G3.7 CELE_F47B7.2 CELE_M04D5.1 CELE_W01A8.8 CELE_Y64G10A.7 CELE_ZK1307.8 W03G11.3 Y71H2AM.10 anoh-2 apl-1 atgl-1 calu-1 cet-1 cpi-2 daf-7 dbl-1 dnj-7 egl-17 enpl-1 famk-1 lec-2 nid-1 nucb-1 ost-1 pdi-1 pdi-2 pdi-6 sdn-1 sparc srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 sup-17 tag-225 tag-320 timp-1 unc-129	Caenorhabditis elegans
Regulation of HSF1-mediated heat shock response	BAG domain-containing protein BAG family molecular chaperone regulator 1 DUF148 domain-containing protein DnaJ homolog subfamily C member 2 Glycogen synthase kinase-3 Heat shock 70 kDa protein 13 Heat shock 70 kDa protein C Heat shock protein 110 Heat shock protein hsp-1 Heat shock protein hsp-6 Heat shock transcription factor hsf-1 Hikeshi-like domain-containing protein J domain-containing protein MAP kinase-activated protein kinase mak-1 MAP kinase-activated protein kinase mak-2 Mitogen-activated protein kinase mpk-1 Protein kinase domain-containing protein Putative serine/threonine-protein kinase R03D7.5 STI1 domain-containing protein	G5EC99 G5EE04 G5EFT5 K8ERU5 O44739 O61980 P09446 P11141 P27420 P39745 Q05036 Q09595 Q20752 Q21360 Q93372 Q94216 Q965G5 Q9TY07 Q9U2Q9	C44H4.6 CELE_F11F1.1 CELE_F42A6.6 R03D7.5 bag-1 dnj-11 dnj-24 gsk-3 hip-1 hsf-1 hsp-1 hsp-110 hsp-3 hsp-6 hsp70a hsp70c hsp70f mak-1 mak-2 mot-2 mpk-1 sgg-1 stc-1 sur-1 unc-23	Caenorhabditis elegans
Regulation of FZD by ubiquitination	EGF-like domain-containing protein EGF-like domain-containing protein Frizzled-2 Frizzled-4 Polyubiquitin-A Probable E3 ubiquitin-protein ligase plr-1 Protein mom-5 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A0K3AWM6 G5ECQ2 G5EDV1 G5EFK8 O44191 P0CG71 P37165 P49632 Q9U2B7	CELE_F14B4.1 cfz-2 lin-17 mom-5 plr-1 rme-2 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Reduction of cytosolic Ca++ levels	Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calx-beta domain-containing protein Calx-beta domain-containing protein EF-hand domain-containing protein Plasma membrane calcium-transporting ATPase mca-1	G5EEK8 G5EF08 G5EFR6 H2KYP2 Q18136 Q95XP5 Q9TYP9	cal-5 mca-1 mca-2 mca-3 mca-4 ncx-1 ncx-2 sca-1	Caenorhabditis elegans

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