GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **499** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Gap-filling DNA repair synthesis and ligation in TC-NER	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 Cullin-4 Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA ligase 1 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 3 DNA polymerase epsilon catalytic subunit DNA polymerase epsilon subunit 3 DNA polymerase kappa DNA repair and recombination protein RAD54-like DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 Intron-binding protein aquarius Polyubiquitin-A Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor SYF1 Probable DNA polymerase delta small subunit Probable DNA polymerase epsilon subunit 2 Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable replication factor A 73 kDa subunit Probable replication factor C subunit 5 Proliferating cell nuclear antigen Protein isy-1 Putative transcription elongation factor S-II RING-box protein 1 RNA polymerase Rpb4/RPC9 core domain-containing protein RPA_C domain-containing protein Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 UV-stimulated scaffold protein A homolog Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein WD_REPEATS_REGION domain-containing protein Zinc finger protein 830	G5EFV5 K8F7X5 O02092 O02115 O17245 O44175 O44499 O62218 P0CG71 P16356 P34409 P34429 P34567 P37165 P49632 P52652 P53016 P90829 P91175 P91356 Q09645 Q10051 Q10578 Q17392 Q17684 Q18547 Q18841 Q18963 Q19196 Q19366 Q19537 Q19826 Q20716 Q21554 Q21730 Q22139 Q22798 Q23088 Q23457 Q27474 Q7JKC3 Q86D18 Q93338 Q95PZ4 Q965S0 Q9GR61 Q9N390 Q9N3C9 Q9N3L2 Q9N5K2 Q9U1Q7 Q9U3I0 Q9XVH6	CELE_F53H4.6 CELE_R04F11.3 CELE_T26A5.8 F10C2.4 F12F6.7 F44B9.8 T24H10.1 ama-1 cdk-7 csa-1 cul-4 ddb-1 emb-4 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2h1 gtf-2h3 isy-1 lig-1 math-33 mnat-1 pcn-1 pole-1 pole-2 polk-1 prp-19 rbx-1 rfc-1 rfc-2 rfc-3 rfc-4 rpa-1 rpa-4 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 sel-13 syf-1 ubia ubib ubl-1 ubq-1 ubq-2 usp-7 uvs-1 xpb-1 xpd-1	Caenorhabditis elegans
Formation of the Early Elongation Complex	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIF subunit 2 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase Rpb4/RPC9 core domain-containing protein Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha	G5EFV5 K8F7X5 O01763 O02092 O17245 O44499 P16356 P34567 Q09645 Q10578 Q17558 Q17684 Q19826 Q21338 Q8MYM8 Q93338 Q93594 Q95PZ4 Q95QG8 Q965S0 Q9GR61 Q9N390 Q9N3C9 Q9N3L2 Q9N5K2 Q9TZ93 Q9U3I0 Q9XVH6	ama-1 cbp-20 cbp-80 cdk-7 fcp-1 gtf-2F1 gtf-2F2 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2f1 gtf-2f2 gtf-2h1 gtf-2h3 mnat-1 ncbp-1 ncbp-2 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 spt-4 spt-5 xpb-1 xpd-1	Caenorhabditis elegans
mRNA Capping	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIF subunit 2 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 RNA polymerase Rpb4/RPC9 core domain-containing protein Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme	G5EFV5 K8F7X5 O01763 O02092 O17245 O44499 P16356 P34567 Q09645 Q10578 Q17558 Q17607 Q17684 Q19826 Q21338 Q8MYM8 Q93338 Q93594 Q95PZ4 Q965S0 Q9GR61 Q9N390 Q9N3C9 Q9N3L2 Q9N5K2 Q9U3I0 Q9XVH6 Q9XVS1	ama-1 cbp-20 cbp-80 cdk-7 cel-1 gtf-2F1 gtf-2F2 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2f1 gtf-2f2 gtf-2h1 gtf-2h3 mnat-1 ncbp-1 ncbp-2 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 spt-5 tag-72 xpb-1 xpd-1	Caenorhabditis elegans
Formation of TC-NER Pre-Incision Complex	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 Cullin-4 Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA repair and recombination protein RAD54-like DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 Intron-binding protein aquarius Polyubiquitin-A Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor SYF1 Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Protein isy-1 Putative transcription elongation factor S-II RING-box protein 1 RNA polymerase Rpb4/RPC9 core domain-containing protein UV-stimulated scaffold protein A homolog Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein WD_REPEATS_REGION domain-containing protein XPA C-terminal domain-containing protein Zinc finger protein 830	G5EFV5 K8F7X5 O01422 O02092 O17245 O44499 P0CG71 P16356 P34567 P37165 P49632 P52652 P91001 P91175 Q09645 Q10051 Q10578 Q17392 Q17684 Q18963 Q19826 Q20716 Q21302 Q21554 Q22139 Q23088 Q23457 Q7JKC3 Q86D18 Q93338 Q95PZ0 Q95PZ4 Q965S0 Q9GR61 Q9GS00 Q9N359 Q9N390 Q9N3C9 Q9N3L2 Q9N425 Q9N5K2 Q9U1Q7 Q9U3I0 Q9XVH6	CELE_F53H4.6 T24H10.1 ama-1 cdk-7 csa-1 csn-1 csn-2 csn-3 csn-4 csn-5 csn-6 cul-4 ddb-1 emb-4 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2h1 gtf-2h3 isy-1 math-33 mnat-1 prp-19 rbx-1 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 sel-13 syf-1 ubia ubib ubl-1 ubq-1 ubq-2 usp-7 uvs-1 xpa-1 xpb-1 xpd-1	Caenorhabditis elegans
HSF1 activation	Co-chaperone protein daf-41 Elongation factor 1-alpha Heat shock protein 90 Heat shock transcription factor hsf-1 Histone deacetylase domain-containing protein Transitional endoplasmic reticulum ATPase homolog 2	G5EFT5 P53013 P54812 Q18688 Q23280 Q9U266	cdc-48.2 daf-21 daf-41 eft-3 eft-4 hda-10 hsf-1 p23	Caenorhabditis elegans
Transcriptional regulation by RUNX2	Core-binding factor subunit beta homolog bro-1 Cyclin N-terminal domain-containing protein Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B PPM-type phosphatase domain-containing protein Runt-related transcription factor rnt-1	G5EFQ5 O45926 P34556 Q10653 Q95XK4 Q95ZL9 Q9BLB5	bro-1 cdk-1 cyb-1 cyb-2.1 cyb-2.2 mab-2 ncc-1 ppm-1.D ppm-1.d rnt-1 run-1	Caenorhabditis elegans
SHC1 events in ERBB2 signaling	EGF-like domain-containing protein EGF-like domain-containing protein Receptor tyrosine-protein kinase let-23	G5EFK8 O44191 P24348	CELE_F14B4.1 kin-7 let-23 rme-2	Caenorhabditis elegans
ERBB2 Regulates Cell Motility	EGF-like domain-containing protein EGF-like domain-containing protein FH2 domain-containing protein Protein memo-1 homolog Ras-like GTP-binding protein rhoA Receptor tyrosine-protein kinase let-23 WAPL domain-containing protein	G5EFK8 O44191 P24348 Q19479 Q22038 Q22915 Q7JP75	CELE_F14B4.1 cyk-1 inft-2 kin-7 let-23 memo-1 rho-1 rhoa rme-2 tag-253	Caenorhabditis elegans
GRB2 events in EGFR signaling	EGF-like domain-containing protein EGF-like domain-containing protein Ras protein let-60 Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5 Son of sevenless homolog	G5EFK8 O44191 P22981 P24348 P29355 Q9N5D3	CELE_F14B4.1 kin-7 let-23 let-341 let-60 lin-34 rme-2 sem-5 sos-1	Caenorhabditis elegans
SHC1 events in EGFR signaling	EGF-like domain-containing protein EGF-like domain-containing protein Ras protein let-60 Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5 Son of sevenless homolog	G5EFK8 O44191 P22981 P24348 P29355 Q9N5D3	CELE_F14B4.1 kin-7 let-23 let-341 let-60 lin-34 rme-2 sem-5 sos-1	Caenorhabditis elegans
Vitamin D (calciferol) metabolism	3-ketosteroid oxygenase Nuclear hormone receptor family member daf-12 Nuclear hormone receptor family member nhr-48 Nuclear hormone receptor family member nhr-8 Suppressor of lurcher protein 1	G5EFF5 H2KYS3 Q93212 Q94407 Q9XYB7	XL285 daf-12 daf-20 daf-9 mig-7 nhr-48 nhr-8 sol-1	Caenorhabditis elegans
Sema4D induced cell migration and growth-cone collapse	Guanine nucleotide exchange factor Plexin-2 Ras-like GTP-binding protein rhoA Receptor tyrosine-protein kinase let-23 Rho-associated protein kinase let-502 Sema domain-containing protein Semaphorin-1A Semaphorin-2A	G5EFE1 O45657 P24348 P92199 Q17330 Q22038 Q95XP4 Q9TYS4	kin-7 let-23 let-502 mab-20 plx-2 rhgf-1 rho-1 rhoa sema-1a smp-1 smp-2	Caenorhabditis elegans
Ligand-independent caspase activation via DCC	Cell death protein 3 Netrin receptor unc-40	G5EF96 P42573	ced-3 unc-40	Caenorhabditis elegans
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Inositol 1,4,5-trisphosphate receptor itr-1 Stromal interaction molecule 1 Transient receptor ion channel domain-containing protein	G5EF60 Q8I6Y9 Q9Y0A1	dec-4 itr-1 lfe-1 stim-1 trp-2	Caenorhabditis elegans
Reuptake of GABA	Transporter	G5EF43	snf-11	Caenorhabditis elegans
Surfactant metabolism	ABC transporter domain-containing protein Aspartic protease 4 G-protein coupled receptors family 1 profile domain-containing protein GATA-type domain-containing protein GATA-type domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein Saposin B-type domain-containing protein Saposin B-type domain-containing protein Sodium-dependent phosphate transport protein 2B TEStin (Human testis-derived transcript) homolog Transcription factor elt-1 Transcription factor elt-2 Transcription factor elt-6 Transcription factor elt-7	G5EF25 G5EF71 G5EGN3 O61924 P28515 Q10655 Q17525 Q18276 Q18279 Q19779 Q1ZXT2 Q20827 Q21966 Q23530 Q9TXV8	CELE_F55D10.4 CELE_ZK563.2 abt-4 ador-1 asp-4 elt-1 elt-2 elt-6 elt-7 gtr-1 med-1 med-2 spp-10 spp-8 tes-1	Caenorhabditis elegans
GDP-fucose biosynthesis	GDP-L-fucose synthase GDP-fucose transporter GDP-mannose 4,6 dehydratase 1 GHMP kinase N-terminal domain-containing protein L-fucokinase domain-containing protein	G5EER4 Q0PDK5 Q18214 Q18801 Q968A5	C26D10.4 CELE_K03H1.13 bre-1 ger-1 gmd-1 nstp-10	Caenorhabditis elegans	G85196CF
Reduction of cytosolic Ca++ levels	Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calx-beta domain-containing protein Calx-beta domain-containing protein EF-hand domain-containing protein Plasma membrane calcium-transporting ATPase mca-1	G5EEK8 G5EF08 G5EFR6 H2KYP2 Q18136 Q95XP5 Q9TYP9	cal-5 mca-1 mca-2 mca-3 mca-4 ncx-1 ncx-2 sca-1	Caenorhabditis elegans
Ion homeostasis	Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II Calx-beta domain-containing protein Calx-beta domain-containing protein EF-hand domain-containing protein Inositol 1,4,5-trisphosphate receptor itr-1 Plasma membrane calcium-transporting ATPase mca-1 Stromal interaction molecule 1 Transient receptor ion channel domain-containing protein Troponin I 1 Troponin I 2 Troponin I 3 Troponin I 4 cAMP-dependent protein kinase catalytic subunit	G5EEK8 G5EF08 G5EF60 G5EFR6 H2KYP2 O44572 O62305 P21137 Q18136 Q20334 Q8I6Y9 Q95XP5 Q9GYF1 Q9TYP9 Q9XUN9 Q9Y0A1	cal-5 dec-4 itr-1 kin-1 lfe-1 mca-1 mca-2 mca-3 mca-4 ncx-1 ncx-2 sca-1 stim-1 tni-1 tni-2 tni-3 tni-4 trp-2 unc-27 unc-43	Caenorhabditis elegans
Cyclin E associated events during G1/S transition	Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor G1/S-specific cyclin-E M-phase inducer phosphatase cdc-25.1 M-phase inducer phosphatase cdc-25.2 M-phase inducer phosphatase cdc-25.3 M-phase inducer phosphatase Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2	G5EEJ2 O01501 O44552 O44628 O61847 P30634 Q17941 Q21762 Q9XTG7	akt-1 akt-2 cdc-25.1 cdc-25.2 cdc-25.3 cdc-25.4 cdk-2 cki-2 cye-1	Caenorhabditis elegans
Myogenesis	Helix-loop-helix protein hlh-2 MEF2 transcription factor homolog Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 Myoblast determination protein 1 homolog Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein	G5EEG9 G5EFV1 O44514 P22980 P91267 Q17446 Q8MXI4 Q93344 Q9U325 Q9U3L3 Q9XX60 Q9XXC0	C49C3.10 CELE_F21F3.2 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 CeMef-2 gska-3 gskl-2 hlh-1 hlh-2 mef-2 pmk-1 pmk-2 pmk-3	Caenorhabditis elegans
FGFR1c and Klotho ligand binding and activation	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15	G5EEF1 Q10656 Q18758 Q9TZA0	egl-15 egl-17 klo-1 klo-2	Caenorhabditis elegans
betaKlotho-mediated ligand binding	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15	G5EEF1 Q10656 Q18758 Q9TZA0	egl-15 egl-17 klo-1 klo-2	Caenorhabditis elegans
FGFR2b ligand binding and activation	EGL-17 Myoblast growth factor receptor egl-15 Protein let-756	G5EEF1 Q10656 Q11184	egl-15 egl-17 let-756	Caenorhabditis elegans
FGFR3c ligand binding and activation	EGL-17 Myoblast growth factor receptor egl-15 Protein let-756	G5EEF1 Q10656 Q11184	egl-15 egl-17 let-756	Caenorhabditis elegans

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