GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **499** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
RHOD GTPase cycle	Adducin-related protein 1 Adducin-related protein 2 Alpha-actinin, sarcomeric Anion exchange protein C2 domain-containing protein Caveolin-1 Caveolin-2 Cortactin-binding protein-2 N-terminal domain-containing protein EF-hand domain-containing protein ERGIC-53-like protein F-actin-capping protein subunit beta FH2 domain-containing protein GEX Interacting protein GTPase-activating protein pac-1 Golgin subfamily A conserved domain-containing protein Intermediate filament protein ifa-1 Intermediate filament protein ifa-2 Intermediate filament protein ifa-3 Intermediate filament protein ifa-4 Intermediate filament protein ifb-1 Intermediate filament protein ifb-2 Intermediate filament protein ifc-1 Intermediate filament protein ifc-2 Intermediate filament protein ifd-1 Intermediate filament protein ifd-2 Intermediate filament protein ifp-1 Lamin-1 Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Nicotinic receptor-associated protein 1 Phosphoinositide 3-kinase adapter subunit Plexin-2 Protein let-99 Protein vem-1 Rac GTPase-activating protein 1 Ras-like GTP-binding protein rhoA Ras-related protein Rab-7a Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho-GAP domain-containing protein Rho-GAP domain-containing protein Sema domain-containing protein Serine/threonine-protein kinase VRK1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Target of ERK kinase mpk-1 Torsin-1B Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325	A0A2K5AU23 A0A679L8R0 B3WFV9 G5EDE8 G5EDP9 G5EFU0 H2KY90 H2KZH5 H2KZV6 O01630 O02163 O02365 O02495 O17099 O44782 O45168 O45611 O45657 P34288 P34686 P46941 P90900 P90901 P91330 Q09501 Q10956 Q17955 Q18879 Q19286 Q19289 Q19479 Q19782 Q19848 Q19989 Q20952 Q20981 Q21065 Q21067 Q21341 Q21443 Q22038 Q22622 Q23130 Q23146 Q23158 Q7JP75 Q7K7J0 Q7YZW5 Q86DC6 Q94051 Q95QQ9 Q95XR9 Q9U2A6 Q9U9K0 Q9XUB9 Q9XUS9 U4PRY7	C14A4.8 C49H3.6 CELE_F42G2.5 CELE_F54H5.3 CELE_F58E6.5 CELE_T04C9.1 CELE_T09B4.2 CELE_Y38F2AR.10 CELE_ZC196.2 aap-1 abts-1 add-1 add-2 atn-1 cap-2 cav-1 cav-2 cyk-1 cyk-4 efhd-1 esyt-2 gap gei-18 golg-2 hpo-28 ifa-1 ifa-2 ifa-3 ifa-4 ifb-1 ifb-2 ifc-1 ifc-2 ifd-1 ifd-2 ifp-1 ile-1 inft-2 lam-1 let-99 lmn-1 mua-6 nra-1 osm-10 pac-1 pak-2 plx-1 plx-2 rab-7 rga-1 rga-5 rga-8 rho-1 rhoa snb-1 tag-325 toe-2 vang-1 vem-1 vpr-1 vrk-1	Caenorhabditis elegans
RHOB GTPase cycle	Anillin-like protein 2 Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 CRAL-TRIO domain-containing protein Cadherin domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 DH domain-containing protein DH domain-containing protein FH2 domain-containing protein FH2 domain-containing protein Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphoinositide 3-kinase adapter subunit Probable rho GDP-dissociation inhibitor Protein ECT2 Protein kinase domain-containing protein Protein let-99 Protein vav-1 Rac GTPase-activating protein 1 Ras-like GTP-binding protein rhoA Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho guanine nucleotide exchange factor osg-1 Rho-GAP domain-containing protein Rho-associated protein kinase let-502 SH2 domain-containing protein START domain-containing protein Stomatin-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tight junction protein ZO-1 Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A4V0IKG6 A0A4V0ILM7 A5PEW5 D6VPA1 F0IWT2 G5EDP9 G5EEN8 G5EFE1 H2KY90 H2KYI7 H2KZH5 H2KZV6 O02495 O17772 O44326 O45611 O61528 P91406 P92199 Q09994 Q10953 Q17777 Q18825 Q18879 Q19479 Q19958 Q20440 Q20496 Q21341 Q21653 Q22038 Q23130 Q45FX5 Q5F4U0 Q7JP75 Q8I103 Q93332 Q94051 Q965J0 Q9U364 Q9XUS9	C07B5.4 CELE_T04C9.1 CELE_Y105E8A.25 aap-1 aex-4 ani-2 bar-1 cav-1 cav-2 cdh-10 cgef-1 cyk-1 cyk-4 daam-1 ect-2 ephx-1 gck-4 gcp-2.1 gcp-2.2 gei-1 hmp-2 hum-7 inft-2 let-502 let-99 osg-1 pes-7 pkn-1 pvl-1 rga-1 rga-5 rhgf-1 rhi-1 rho-1 rhoa ric-4 snb-1 spy-1 sto-2 tag-81 toe-2 unc-73 vang-1 vav-1 wrm-1 zoo-1	Caenorhabditis elegans
RHOA GTPase cycle	ACB domain-containing protein Anillin-like protein 2 Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 CED-5 CRAL-TRIO domain-containing protein Cadherin domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Conserved regulator of innate immunity protein 3 DH domain-containing protein DH domain-containing protein DH domain-containing protein DH domain-containing protein F-BAR domain-containing protein FH2 domain-containing protein FH2 domain-containing protein Formin-homology and zinc finger domains protein 1 Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor Moesin/ezrin/radixin homolog 1 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Peroxisomal Membrane Protein related Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein ECT2 Protein kinase domain-containing protein Protein let-99 Protein vav-1 Protein vav Rac GTPase-activating protein 1 Ras-like GTP-binding protein rhoA Rho GTPase-activating protein 20 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho guanine nucleotide exchange factor osg-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-associated protein kinase let-502 SH2 domain-containing protein SH3 domain-containing protein START domain-containing protein Sec1 family domain-containing protein 1 Stomatin-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tight junction protein ZO-1 UBX domain-containing protein Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A0K3AW57 A0A2K5AU23 A0A4V0IKG6 A0A4V0ILM7 A5PEW5 D6VPA1 F0IWT2 G5EDP9 G5EDU3 G5EEN3 G5EEN8 G5EF62 G5EF80 G5EFE1 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 O01443 O01847 O02495 O17772 O17905 O44326 O45611 O45628 O61528 P34489 P46941 P91406 P92199 Q09994 Q10953 Q17777 Q18598 Q18825 Q18879 Q19370 Q19479 Q19958 Q20364 Q20440 Q20496 Q21018 Q21341 Q21430 Q21653 Q22038 Q23130 Q45FX5 Q5F4U0 Q7JP75 Q8I103 Q93332 Q94051 Q965J0 Q9U364 Q9XTZ5 Q9XUS9 Q9XW53 S6EZU2 U4PAK0	C07B5.4 CELE_F23H11.4 CELE_H40L08.1 CELE_T04C9.1 CELE_Y105E8A.25 PLD aap-1 aex-4 ani-2 bar-1 cav-1 cav-2 cdh-10 ced-5 cgef-1 cri-3 cyk-1 cyk-4 daam-1 ect-2 ephx-1 fozi-1 frm-3 gck-4 gcp-2.1 gcp-2.2 gei-1 hmp-2 hum-7 inft-2 let-502 let-99 maa-1 osg-1 pes-7 pix-1 pkn-1 pld-1 pmp-2 pvl-1 rga-1 rga-2 rga-4 rga-5 rga-6 rga-8 rga-9 rhgf-1 rhgf-2 rhi-1 rho-1 rhoa ric-4 sly-1 snb-1 spv-1 spy-1 srgp-1 sto-2 tag-325 tag-81 tiam-1 toe-2 uig-1 unc-73 vang-1 vav-1 wrm-1 zoo-1	Caenorhabditis elegans
RHO GTPases activate PKNs	14-3-3-like protein 1 14-3-3-like protein 2 M-phase inducer phosphatase cdc-25.1 M-phase inducer phosphatase cdc-25.2 M-phase inducer phosphatase cdc-25.3 M-phase inducer phosphatase Protein phosphatase 1 regulatory subunit 14B Ras-like GTP-binding protein rhoA Ras-related protein ced-10 Serine/threonine-protein phosphatase PP1-alpha cGMP-dependent protein kinase interacting domain-containing protein non-specific serine/threonine protein kinase protein kinase C	A0A4V0ILM7 G5ECD7 O44552 O44628 P30634 P41932 Q03206 Q20655 Q21762 Q22038 Q27497 Q7YX00 Q9UA62	CELE_F55C10.5 CELE_W04B5.5 cdc-25.1 cdc-25.2 cdc-25.3 cdc-25.4 ced-10 ftt-1 ftt-2 gsp-1 mel-11 par-5 pkn-1 rac-1 rho-1 rhoa	Caenorhabditis elegans
RHO GTPases Activate WASPs and WAVEs	Actin-1 Actin-2 Actin-3 Actin-4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog Inactive tyrosine-protein kinase kin-32 Membrane-associated protein gex-3 Mitogen-activated protein kinase mpk-1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Probable actin-related protein 2/3 complex subunit 2 Probable actin-related protein 2/3 complex subunit 3 Probable actin-related protein 2/3 complex subunit 4 Protein BRICK1 Ras-related protein ced-10 SH3 domain-containing protein SPIN90/Ldb17 leucine-rich domain-containing protein Sex muscle abnormal protein 5 Tyrosine-protein kinase abl-1 WASH complex subunit homolog 1 Wiskott-Aldrich syndrome protein family member	A0A3P6PCS5 A5Z2X2 O18195 O44518 O61861 P03949 P0DM41 P0DM42 P10984 P10986 P29355 P39745 P53489 P55163 P58798 Q03206 Q05062 Q10929 Q8WTM6 Q95PX0 Q95YD4 Q9N372 Q9N4I0 Q9XVK6 Q9XWV3	CELE_Y55F3AM.5 CELE_Y57G11C.1147 abi-1 abl-1 act-1 act-2 act-3 act-4 arp-2 arx-1 arx-2 arx-3 arx-4 arx-5 arx-6 arx-7 cdc-42 ced-10 ddl-2 gex-2 gex-3 kin-32 mpk-1 nck-1 rac-1 sem-5 sur-1 wve-1	Caenorhabditis elegans
RHO GTPases Activate Formins	Actin-1 Actin-2 Actin-3 Actin-4 Cell division control protein 42 homolog DiSHevelled related DiSHevelled related FH2 domain-containing protein FH2 domain-containing protein Formin-homology and zinc finger domains protein 1 Ras-like GTP-binding protein rhoA Ras-related protein ced-10 Rho-GAP domain-containing protein Segment polarity protein dishevelled homolog mig-5 Tyrosine protein-kinase src-1 WAPL domain-containing protein	A0A0K3AUI8 D6VPA1 G5EE56 P0DM41 P0DM42 P10984 P10986 P34489 Q03206 Q05062 Q18239 Q19370 Q19479 Q22038 Q22227 Q7JP75	act-1 act-2 act-3 act-4 cdc-42 ced-10 cyk-1 daam-1 dsh-1 dsh-2 fozi-1 inft-2 mig-5 rac-1 rho-1 rhoa src-1 srgp-1	Caenorhabditis elegans
RET signaling	GDNF/GAS1 domain-containing protein Protein kinase domain-containing protein	A0A2C9C3B4 Q95XG5	CELE_F09G2.1 CELE_Y69A2AR.31	Caenorhabditis elegans
RAF/MAP kinase cascade	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Inactive tyrosine-protein kinase kin-32 Kringle domain-containing protein Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Ral guanine nucleotide dissociation stimulator-like 1 Rap guanine nucleotide exchange factor Ras guanyl-releasing protein 3 Ras protein let-60 Ras-GEF domain-containing family member 1B Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5 Son of sevenless homolog Spectrin alpha chain Spectrin beta chain Spectrin beta chain Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Tyrosine-protein phosphatase Lar-like Uncharacterized protein C50C3.2	A0A1I6CMA1 E0AHA7 G5EDB9 G5EDP9 G5EE56 G5EEF1 G5EFK8 G5EFW3 H2KZU7 O44191 P22981 P24348 P29355 P34367 P39745 P91823 Q10656 Q11184 Q18758 Q19770 Q19852 Q21046 Q21408 Q94125 Q95YD4 Q95ZV7 Q9BMN8 Q9N413 Q9N5D3 Q9TZA0 Q9XVQ7 W6RS10	C50C3.2/C50C3.3 CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_R05G6.10 CELE_T22A3.6 aap-1 age-1 ddr-2 egl-15 egl-17 kin-32 kin-36 kin-7 klo-1 klo-2 let-23 let-341 let-60 let-756 lin-34 mpk-1 ptp-3 pvf-1 pxf-1 ra-gef rgef-1 rgl-1 rme-2 sem-5 sma-1 sos-1 spc-1 src-1 sur-1 svh-2 svh-4 unc-70	Caenorhabditis elegans
RAF activation	14-3-3-like protein 1 14-3-3-like protein 2 BRCA1-associated protein homolog 2 GTP binding protein Kinase suppressor of Ras A Leucine-rich repeat protein soc-2 Mitochondrial prohibitin complex protein 1 Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Raf homolog serine/threonine-protein kinase Ras protein let-60 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase par-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Serine/threonine-protein phosphatase PP1-alpha Serine/threonine-protein phosphatase	A9UJN4 G5EC18 G5EFD2 G5EGA7 G5EGK8 O18178 P22981 P41932 Q07292 Q09543 Q20655 Q22875 Q27497 Q95QN6 Q9BKU4 Q9NAC7 Q9TW45	CELE_Y53F4B.1 Ras2 brap-2 ftt-1 ftt-2 gsp-1 ksr-1 let-60 let-92 lin-34 lin-45 paa-1 par-1 par-5 phb-1 pph-1 pptr-1 pptr-2 raf-1 ras-2 soc-2 sur-8	Caenorhabditis elegans
RAC3 GTPase cycle	Amino acid transporter Amino acid transporter Arf-GAP domain-containing protein CRAL-TRIO domain-containing protein Cadherin-4 Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Excitatory amino acid transporter GTPase-activating protein pac-1 Glutamate carboxypeptidase 2 homolog MAGUK family Membrane-associated protein gex-3 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphoinositide 3-kinase adapter subunit Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein let-99 Protein unc-112 Protein vav-1 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rac GTPase-activating protein 1 Rap guanine nucleotide exchange factor 1 Ras-related protein Rab-7a Ras-related protein ced-10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 Wiskott-Aldrich syndrome protein family member t-SNARE protein aex-4	A0A0K3AR51 A0A2K5AU23 A5PEW5 A5Z2X2 G5EDP9 G5EEN8 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 H2KZX7 O01443 O01847 O02495 O17590 O18210 O44518 O45611 O61460 O61528 P03949 P34288 P46549 P46941 P55163 P91406 Q03206 Q05062 Q10901 Q10929 Q17850 Q18685 Q18879 Q19319 Q19370 Q19467 Q20496 Q21341 Q21353 Q21751 Q22682 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q95XW5 Q9GYK2 Q9UAY8 Q9XUS9 Q9XVK6	C05D9.3 CELE_F22G12.5 CELE_F23H11.4 CELE_T04C9.1 CELE_Y34B4A.4 CELE_Y57G11C.1147 aap-1 abi-1 abl-1 aex-4 cav-1 cav-2 cdc-42 cdh-4 ced-10 cgef-1 cyk-1 cyk-4 gap gcp-2.1 gcp-2.2 gex-2 gex-3 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 kin-18 let-99 magu-1 max-2 ocrl-1 pac-1 pak-1 pak-2 rab-7 rac-1 rga-1 rga-5 rga-6 rga-8 rhi-1 ric-4 snb-1 srgp-1 sulu syd-1 tag-325 tag-81 tiam-1 toe-2 unc-112 unc-73 vab-1 vang-1 vav-1 wve-1	Caenorhabditis elegans
RAC2 GTPase cycle	Arf-GAP domain-containing protein Armadillo repeat-containing domain-containing protein CED-5 CRAL-TRIO domain-containing protein Cadherin-4 Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Glutamate carboxypeptidase 2 homolog MAGUK family Membrane-associated protein gex-3 Metaxin-1 homolog N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein let-99 Protein vav-1 Rac GTPase-activating protein 1 Ras-related protein Rab-18 Ras-related protein Rab-7a Ras-related protein ced-10 Ras-related protein rac-2 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein SAM50-like protein gop-3 SH3 domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Target of ERK kinase mpk-1 Uncharacterized integrin beta-like protein C05D9.3 Vang-like protein WAPL domain-containing protein Wiskott-Aldrich syndrome protein family member	A0A0K3AR51 A0A2K5AU23 A5Z2X2 G5EDP9 G5EDU3 G5EEN3 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV6 O01847 O02495 O17772 O44518 O45503 O45611 O61460 O61528 P46549 P46576 P55163 P91406 Q03206 Q05062 Q10929 Q17850 Q18879 Q19319 Q19467 Q20496 Q21341 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q94124 Q94125 Q95XW5 Q9BL44 Q9GYK2 Q9U1V2 Q9XUS9 Q9XVK6	C05D9.3 CELE_F22G12.5 CELE_T04C9.1 CELE_Y57G11C.1147 CELE_Y67A10A.7 CELE_Y71H2AM.12 PLD aap-1 abi-1 age-1 cav-1 cav-2 cdc-42 cdh-4 ced-10 ced-5 cgef-1 cyk-1 cyk-4 gcp-2.1 gcp-2.2 gex-2 gex-3 git-1 gop-3 kin-18 let-99 magu-1 max-2 mtx-1 pak-1 pak-2 pes-7 pld-1 rab-7 rac-1 rac-2 rga-1 rga-5 rga-8 rhi-1 snb-1 sulu syd-1 tiam-1 toe-2 unc-73 vab-1 vang-1 vav-1 wve-1	Caenorhabditis elegans
RAC1 GTPase cycle	Amino acid transporter Amino acid transporter Arf-GAP domain-containing protein C2 DOCK-type domain-containing protein CED-5 CRAL-TRIO domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Chimerin 2 Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Excitatory amino acid transporter F-BAR domain-containing protein FYVE, RhoGEF and PH domain-containing protein tag-77 Formin-homology and zinc finger domains protein 1 GTPase-activating protein pac-1 Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor Guanine nucleotide-binding protein alpha-12 subunit MAGUK family Membrane-associated protein gex-3 Moesin/ezrin/radixin homolog 1 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Partitioning defective protein 6 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein ECT2 Protein let-99 Protein unc-112 Protein vav-1 Protein vav Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rac GTPase-activating protein 1 Ras-related protein Rab-7a Ras-related protein ced-10 Rho GTPase-activating protein 20 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH2 domain-containing protein SH3 domain-containing protein SH3 domain-containing protein START domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase mrck-1 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Son of sevenless homolog Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A0K3AR51 A0A2K5AU23 A0A4V0ILM7 A5PEW5 A5Z2X2 F0IWT2 G5EDP9 G5EDU3 G5EEN3 G5EEN8 G5EF62 G5EF80 G5EFE1 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 O01583 O01847 O02495 O17772 O17905 O18210 O44518 O45611 O61460 O61528 P03949 P34288 P34489 P46549 P46941 P55163 P91406 Q03206 Q05062 Q10901 Q10929 Q17850 Q18685 Q18879 Q19370 Q19467 Q19572 Q20440 Q20487 Q20496 Q21025 Q21341 Q21353 Q21430 Q21751 Q22682 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q94125 Q95XW5 Q965J0 Q965N4 Q9GYK2 Q9N5D3 Q9NAN2 Q9U364 Q9UAY8 Q9XUS9 Q9XVH4 Q9XVI0 Q9XVK6 Q9XW53 U4PAK0 X5LX76	C05D9.3 CELE_F22G12.5 CELE_F23H11.4 CELE_F46H5.4 CELE_T04C9.1 CELE_Y105E8A.25 CELE_Y57G11C.1147 PLD aap-1 abi-1 abl-1 aex-4 age-1 cav-1 cav-2 cdc-42 ced-10 ced-5 cgef-1 chin-1 citk-1 citk-2 cyk-1 cyk-4 ect-2 ephx-1 fozi-1 frm-3 gap gcp-2.1 gcp-2.2 gei-1 gex-2 gex-3 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 gpa-12 hum-7 kin-18 let-341 let-99 magu-1 max-2 mrck-1 pac-1 pak-1 pak-2 par-6 pes-7 pix-1 pkn-1 pld-1 rab-7 rac-1 rga-1 rga-2 rga-5 rga-8 rga-9 rhgf-1 rhi-1 ric-4 rlbp-1 snb-1 sos-1 spv-1 srgp-1 sulu syd-1 tag-325 tag-77 tag-81 tiam-1 toe-2 uig-1 unc-112 unc-73 vab-1 vang-1 vav-1 wve-1	Caenorhabditis elegans
RAB geranylgeranylation	GTP-binding protein Rhes Geranylgeranyl transferase type-2 subunit alpha Probable geranylgeranyl transferase type-2 subunit beta RAB family RAB family RAB family RAB family Rab proteins geranylgeranyltransferase component A 1 Rab27 Rab8 Ras and EF-hand domain-containing protein homolog Ras-related protein Rab-10 Ras-related protein Rab-10 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-21 Ras-related protein Rab-2 Ras-related protein Rab-2A Ras-related protein Rab-2A Ras-related protein Rab-30 Ras-related protein Rab-33 Ras-related protein Rab-35 Ras-related protein Rab-3 Ras-related protein Rab-7a Ras-related protein Rab Ras-related protein rab-11.1 Ras-related protein rab-39 Ras-related protein rab-6.1 Ras-related protein rab-6.2 small monomeric GTPase	A0A2C9C2Y0 G5EBF0 G5EBS5 G5EFA6 G5EFC1 O01803 O17788 O17789 P34213 P41992 P91857 Q18969 Q1ZXR4 Q1ZXV0 Q20365 Q21137 Q22045 Q22782 Q22908 Q23146 Q8MXS1 Q93874 Q94148 Q94986 Q9BKQ5 Q9TYY0 Q9U1W9 Q9U2C3 Q9UAQ6 Q9XWZ3	CELE_M57.2 CELE_ZK669.5 aex-6 ggtb-1 glo-1 rab-1 rab-10 rab-11.1 rab-11.2 rab-14 rab-18 rab-19 rab-21 rab-3 rab-30 rab-33 rab-35 rab-37 rab-39 rab-5 rab-6.1 rab-6.2 rab-7 rab-8 rab27 rab8 rabr-1 rabr-3 rabr-4 rep-1 rsef-1 tag-312 unc-108	Caenorhabditis elegans
Proton/oligopeptide cotransporters	Peptide transporter 3 Peptide transporter family 1 Peptide transporter family 2	O01840 Q17758 Q21219	cpta cptb opt-1 opt-2 opt-3 pep-1 pep-2 pept-1 pept-2 pept-3	Caenorhabditis elegans
Proton-coupled monocarboxylate transport	Contactin rig-6 MFS domain-containing protein MFS domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein	G5ECR3 H2KZ60 H2L0E6 O17328 Q22109 Q93896 Q9UAT3	mct-1 mct-2 mct-3 mct-4 mct-5 mct-6 rig-6 slcf-1	Caenorhabditis elegans
Protein methylation	Electron transfer flavoprotein beta subunit lysine methyltransferase homolog Electron transfer flavoprotein subunit beta Elongation factor 1-alpha Protein-lysine N-methyltransferase CELE_F29B9.1 Protein-lysine N-methyltransferase M142.8 Protein-lysine methyltransferase C42C1.13 Transitional endoplasmic reticulum ATPase homolog 2	A7IQW5 O01503 P53013 P54812 Q5WRN3 Q9GYH9 Q9TXI4	C37A2.6 C42C1.13 CELE_F23C8.5 CELE_F29B9.1 M142.8 cdc-48.2 eft-3 eft-4	Caenorhabditis elegans
Prostanoid ligand receptors	G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Neuropeptide receptor 18 Probable G-protein coupled receptor C06G4.5	A0A0K3AXD3 A0A3B1DQQ4 P34311 Q09502 Q20841 Q23033 Q9N452	C06G4.5 npr-16 npr-18 npr-23 npr-24 npr-26 npr-28	Caenorhabditis elegans
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5 alpha-1,2-Mannosidase	P90787 Q18788	C52E4.5 mans-1	Caenorhabditis elegans	G70323CJ
Processing of Capped Intron-Containing Pre-mRNA	B30.2/SPRY domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage stimulation factor 50 kDa subunit DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 DUF3453 domain-containing protein General transcription factor IIF subunit 2 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein K homolog K Homology domain-containing protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase Polyadenylation and cleavage factor homolog 11 Pre-mRNA 3'-end-processing factor FIP1 Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable cleavage and polyadenylation specificity factor subunit 1 Probable cleavage and polyadenylation specificity factor subunit 2 Probable splicing factor, arginine/serine-rich 2 Probable splicing factor, arginine/serine-rich 3 Probable splicing factor, arginine/serine-rich 4 Probable splicing factor, arginine/serine-rich 6 Probable splicing factor, arginine/serine-rich 7 Protein clpf-1 Putative RNA-binding protein PTB-1a Putative RNA-binding protein R05D3.8 RNA polymerase Rpb4/RPC9 core domain-containing protein RNA-binding protein 5 RNA-binding protein FUS RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein Schlafen-like protein 2 Suppressor of forked domain-containing protein Transcription initiation factor IIF subunit alpha pre-mRNA 3' end processing protein pfs-2	A0A164D3G3 B9WRU1 C1P629 D0G911 G5EDV3 O01159 O01763 O02092 O16929 O17403 O18219 O45577 O62213 P16356 P34541 P52874 P91277 P91306 P91398 Q09345 Q09511 Q10578 Q17558 Q17684 Q18265 Q18409 Q18999 Q19614 Q19826 Q19864 Q19866 Q22037 Q23120 Q4W5P0 Q7YTG9 Q8MXR2 Q8MYM8 Q93233 Q93338 Q93594 Q93716 Q95PY8 Q95QR5 Q95Y67 Q965S0 Q9BIB7 Q9BIC2 Q9GR61 Q9N3C9 Q9N4C2 Q9N5K2 Q9NEW6 Q9NLD1 Q9U2P3 Q9U3I0 Q9XTZ2 Q9XVH6 U4PCM1	CELE_Y57G11A.5 CELE_ZK616.1 R05D3.8 ama-1 cbp-20 cbp-80 cey-1 cey-2 cey-3 cey-4 cfim-1 cfim-2 clpf-1 cpf-1 cpf-2 cpsf-1 cpsf-2 cpsf-3 cpsf-4 fipp-1 fust-1 gtf-2F1 gtf-2F2 gtf-2f1 gtf-2f2 hrp-1 hrp-2 hrpf-1 hrpf-2 hrpk-1 hrpl-1 hrpr-1 hrpu-1 ncbp-1 ncbp-2 pabp-2 pap-1 pcf-11 pes-4 pfs-2 ptb-1 rbm-5 rbp-1 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 rsp-2 rsp-3 rsp-4 rsp-6 rsp-7 rsp-8 sqd-1 srp-1 srp-2 srp-4 suf-1 symk-1 tofu-2	Caenorhabditis elegans
Presynaptic depolarization and calcium channel opening	EF-hand domain-containing protein Guanylate kinase/L-type calcium channel beta subunit domain-containing protein SH3 domain-containing protein STarGazin (Mammalian calcium channel) homolog STarGazin (Mammalian calcium channel) homolog Voltage-dependent calcium channel unc-36	A0A078BQJ0 A0A3B1E663 G5EBI8 G5EDT2 O01661 P34374	STG-1 ccb-1 ccb-2 stg-1 stg-2 unc-2 unc-36 unc-72	Caenorhabditis elegans
Prednisone ADME	Glucuronosyltransferase NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein SERPIN domain-containing protein SERPIN domain-containing protein Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein	A9Z1L1 G5ECY2 G5EE40 G5EFH4 O17365 O45520 P91020 P91997 P91998 Q17568 Q18287 Q18903 Q19082 Q19651 Q21274 Q22352 Q23320 Q9NAI5 Q9U2J5 Q9XVQ1	C01G5.5 C07D8.6 C28G1.2 C56G3.2 CELE_F15D3.4 CELE_F44G3.7 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_ZC443.1 exc-15 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 ugt-57	Caenorhabditis elegans
Pre-NOTCH Processing in Golgi	CUB domain-containing protein EGF-like domain-containing protein Protein lin-12 Suppressor/enhancer of lin-12 protein 9	O17528 P14585 P90891 Q21850	CELE_F55H12.3 CELE_R08E3.1 lin-12 sel-9	Caenorhabditis elegans
Postmitotic nuclear pore complex (NPC) reformation	Apple domain-containing protein GTP-binding nuclear protein ran-1 Nuclear Pore complex Protein Nuclear pore complex protein 15 Nuclear pore complex protein 5 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup98-Nup96 Nucleoporin SEH1 Protein SEC13 homolog Ran GTPase-activating protein 2 Regulator of chromosome condensation SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier WD_REPEATS_REGION domain-containing protein	G5ECB4 G5EEH9 O17915 O45933 P34342 P34343 P55853 Q17872 Q18211 Q19131 Q22078 Q8T8M4 Q95017 Q9N4A7	CeSec13R npp-10 npp-15 npp-18 npp-2 npp-20 npp-23 npp-5 npp-6 nup133 ran-1 ran-2 ran-3 sec-13 smo-1 smt3 srap-1 sumo ubc-9	Caenorhabditis elegans
Post-translational protein phosphorylation	Amyloid-beta-like protein Anoctamin Apolipoprotein L, 1 Apolipoprotein L3-like BMP-like protein unc-129 Calumenin-like protein Cystatin cpi-2 DUF19 domain-containing protein Dauer larva development regulatory growth factor daf-7 Disintegrin and metalloproteinase domain-containing protein 10 homolog EGL-17 Endoplasmin homolog Extracellular serine/threonine protein kinase CeFam20 Fibronectin type-III domain-containing protein Galectin domain-containing protein Glucosidase 2 subunit beta J domain-containing protein Multiple epidermal growth factor-like domains protein 6 NTR domain-containing protein NUCleoBindin homolog Nidogen PNPLA domain-containing protein PNPLA domain-containing protein Patanin-like phospholipase domain-containing protein atgl-1 Probable syndecan Protein dbl-1 Protein disulfide-isomerase 1 Protein disulfide-isomerase 2 Protein disulfide-isomerase A6 homolog Putative alpha-L-fucosidase Putative metalloproteinase inhibitor tag-225 SERPIN domain-containing protein SERPIN domain-containing protein SPARC Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Sulfhydryl oxidase Thioredoxin domain-containing protein Transmembrane protein 132 homolog VWFA domain-containing protein	A9Z1L1 G5EBH7 G5EBY8 G5EC87 G5ECM9 G5ECY2 G5EE40 G5EEF1 G5EEL5 G5EFD9 G5EFH4 G5EFX3 H2FLL2 H2KZY5 H2L2L3 O17365 O45520 P34714 P49713 P50605 P91189 P92172 Q09EE8 Q10651 Q11067 Q11186 Q17770 Q17967 Q18048 Q18096 Q18287 Q18948 Q19651 Q20684 Q21265 Q21267 Q22235 Q8MQ51 Q8WQF7 Q8WQF8 Q93791 Q9BL47 Q9N5Z7 Q9XTW2 Q9XVQ1	B0524.2 C16E9.1 C18E9.7 C28G1.2 CELE_D1054.1 CELE_F07F6.7 CELE_F07F6.8 CELE_F15D3.4 CELE_F44G3.7 CELE_F47B7.2 CELE_M04D5.1 CELE_W01A8.8 CELE_Y64G10A.7 CELE_ZK1307.8 W03G11.3 Y71H2AM.10 anoh-2 apl-1 atgl-1 calu-1 cet-1 cpi-2 daf-7 dbl-1 dnj-7 egl-17 enpl-1 famk-1 lec-2 nid-1 nucb-1 ost-1 pdi-1 pdi-2 pdi-6 sdn-1 sparc srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 sup-17 tag-225 tag-320 timp-1 unc-129	Caenorhabditis elegans
Platelet homeostasis	1-alkyl-2-acetylglycerophosphocholine esterase Platelet-activating factor acetylhydrolase homolog 2	G5EGT1 Q22943	paf-1 paf-2	Caenorhabditis elegans

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