GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
RHOH GTPase cycle	ANK_REP_REGION domain-containing protein Amino acid transporter Amino acid transporter Anion exchange protein Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 Caveolin-1 Caveolin-2 Excitatory amino acid transporter Glutamate carboxypeptidase 2 homolog Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial N-acetylated-alpha-linked acidic dipeptidase 2 Probable methionine synthase Probable rho GDP-dissociation inhibitor Protein FAM91A1 Protein kinase domain-containing protein Putative NipSnap protein K02D10.1 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rap-GAP domain-containing protein Ras-related protein Rab-18 Ras-related protein Rab-7a Ras-related protein ced-10 Ras-related protein rac-2 Rho-associated protein kinase let-502 Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Stomatin-2 Synaptobrevin-1 Transitional endoplasmic reticulum ATPase homolog 2 Tyrosine protein-kinase src-1 Tyrosine-protein kinase csk-1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase UBX domain-containing protein 2 Vang-like protein WD_REPEATS_REGION domain-containing protein	A0A061ADQ6 A0A0K3ARA3 B3WFV9 G5EBM6 G5ECJ6 G5EE56 G5EFU0 G5EGQ3 H2KY90 H2KZ40 O02495 O18210 O44326 O62219 P34492 P54812 P91406 P92199 Q03206 Q09582 Q10901 Q10953 Q17850 Q18462 Q18825 Q18879 Q19958 Q20496 Q21353 Q21751 Q22682 Q23146 Q23571 Q23595 Q93332 Q94051 Q94124 Q9BL44 Q9N2W5 Q9N4S6 Q9U3B5 Q9UAY8 Q9XW34 V6CLC2	C34F11.5 CELE_F33H2.2 CELE_K09B11.5 CELE_R151.1 CELE_T25B9.5 CELE_Y110A7A.9 CELE_Y52D5A.2 CELE_Y69E1A.3 CELE_Y71H2AM.12 CELE_ZK792.4 K02D10.1 abts-1 bar-1 cav-1 cav-2 cdc-48.2 ced-10 csk-1 dbt-1 gcp-2.1 gcp-2.2 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 hgap-1 hmp-2 kin-21 let-502 max-2 metr-1 pak-1 pak-2 pvl-1 rab-7 rac-1 rac-2 rhi-1 snb-1 spy-1 src-1 sto-2 ubxn-2 vang-1 wrm-1	Caenorhabditis elegans
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor gar-3	Q9U7D5	gar-3	Caenorhabditis elegans
RAF activation	14-3-3-like protein 1 14-3-3-like protein 2 BRCA1-associated protein homolog 2 GTP binding protein Kinase suppressor of Ras A Leucine-rich repeat protein soc-2 Mitochondrial prohibitin complex protein 1 Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Raf homolog serine/threonine-protein kinase Ras protein let-60 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase par-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Serine/threonine-protein phosphatase PP1-alpha Serine/threonine-protein phosphatase	A9UJN4 G5EC18 G5EFD2 G5EGA7 G5EGK8 O18178 P22981 P41932 Q07292 Q09543 Q20655 Q22875 Q27497 Q95QN6 Q9BKU4 Q9NAC7 Q9TW45	CELE_Y53F4B.1 Ras2 brap-2 ftt-1 ftt-2 gsp-1 ksr-1 let-60 let-92 lin-34 lin-45 paa-1 par-1 par-5 phb-1 pph-1 pptr-1 pptr-2 raf-1 ras-2 soc-2 sur-8	Caenorhabditis elegans
Signaling by EGFR	EGF-like domain-containing protein EGF-like domain-containing protein Leucine-rich repeats and immunoglobulin-like domains protein sma-10 Receptor tyrosine-protein kinase let-23 Tyrosine protein-kinase src-1 WD_REPEATS_REGION domain-containing protein	E0R7L2 G5EE56 G5EFK8 O44191 P24348 Q965M2	CELE_F14B4.1 CELE_Y111B2A.12 kin-7 let-23 rme-2 sma-10 src-1	Caenorhabditis elegans
Sema3A PAK dependent Axon repulsion	Fer-related kinase 1 Ras-related protein ced-10 Sema domain-containing protein Sema domain-containing protein Semaphorin-1A Semaphorin-2A Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Tyrosine protein-kinase src-1	G5EE56 G5EGQ3 Q03206 Q17330 Q17850 Q22146 Q95XP4 Q9TYS4 U4PRY7	ced-10 frk-1 mab-20 max-2 pak-1 plx-1 rac-1 sema-1a smp-1 smp-2 src-1	Caenorhabditis elegans
Rap1 signalling	14-3-3-like protein 1 14-3-3-like protein 2 Raf homolog serine/threonine-protein kinase Rap guanine nucleotide exchange factor 1 Rap-GAP domain-containing protein Rap-GAP domain-containing protein Ras guanyl-releasing protein 3 Ras-related protein Rap-1 cAMP-dependent protein kinase catalytic subunit cGMP-dependent protein kinase egl-4	H2L055 H2L2C2 O76360 P21137 P34578 P41932 Q07292 Q18246 Q19770 Q20655	CELE_F53A10.2 cgk-1 egl-4 epac-1 ftt-1 ftt-2 kin-1 lin-45 odr-9 par-5 raf-1 rap-1 rgef-1 sipa-1	Caenorhabditis elegans
MET activates PTK2 signaling	Inactive tyrosine-protein kinase kin-32 Integrin alpha ina-1 Integrin alpha pat-2 Kringle domain-containing protein Multiple epidermal growth factor-like domains protein 6 Protein kinase domain-containing protein Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Uncharacterized integrin beta-like protein C05D9.3	G5EE56 G5EFX3 H2KZU7 P34446 P91823 Q03600 Q95YD4 Q9GYK2 Q9XVQ7	C05D9.3 CELE_F11E6.8 CELE_T22A3.6 CELE_Y64G10A.7 ina-1 kin-32 pat-2 src-1 svh-2	Caenorhabditis elegans
MET activates RAS signaling	Kringle domain-containing protein Protein kinase domain-containing protein Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog Tyrosine-protein kinase receptor svh-2	H2KZU7 P22981 P29355 P91823 Q9N5D3 Q9XVQ7	CELE_F11E6.8 CELE_T22A3.6 let-341 let-60 lin-34 sem-5 sos-1 svh-2	Caenorhabditis elegans
PI3K/AKT Signaling	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Kringle domain-containing protein Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Protein nipi-3 RICTOR_N domain-containing protein Ras-related protein Rab-18 Ras-related protein ced-10 Ras-related protein rac-2 Receptor tyrosine-protein kinase let-23 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Serine/threonine-protein kinase sgk-1 Sex muscle abnormal protein 5 Stress-activated map kinase-interacting protein 1 homolog Striatin N-terminal domain-containing protein Target of rapamycin complex subunit lst8 Target of rapamycin homolog Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 non-specific serine/threonine protein kinase	A0A1I6CMA1 A0A486WY88 G5EDP9 G5EE56 G5EED4 G5EEF1 G5EFK8 G5EFN2 H2KZU7 O44191 P24348 P29355 P91040 P91823 Q03206 Q10656 Q11184 Q17941 Q18758 Q21046 Q2PJ68 Q94124 Q94125 Q95Q95 Q95ZV7 Q9BL44 Q9N413 Q9NA80 Q9TZA0 Q9UA62 Q9XTG7 Q9XVQ7	CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_T22A3.6 CELE_W04B5.5 CELE_Y71H2AM.12 CeTor aap-1 age-1 akt-1 akt-2 cash-1 ced-10 ddr-2 egl-15 egl-17 kin-36 kin-7 klo-1 klo-2 let-23 let-363 let-756 mlst-8 nipi-3 pvf-1 rac-1 rac-2 rict-1 rme-2 sem-5 sgk-1 sinh-1 src-1 svh-2 svh-4	Caenorhabditis elegans
Reduction of cytosolic Ca++ levels	Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calx-beta domain-containing protein Calx-beta domain-containing protein EF-hand domain-containing protein Plasma membrane calcium-transporting ATPase mca-1	G5EEK8 G5EF08 G5EFR6 H2KYP2 Q18136 Q95XP5 Q9TYP9	cal-5 mca-1 mca-2 mca-3 mca-4 ncx-1 ncx-2 sca-1	Caenorhabditis elegans
Lewis blood group biosynthesis	ATP-dependent DNA helicase Alpha-(1,3)-fucosyltransferase fut-3 DUF38 domain-containing protein F-box C protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein F-box domain-containing protein FTH domain-containing protein FTH domain-containing protein Hexosyltransferase L-Fucosyltransferase	A0A0K3AVC3 A0A1I6CM72 D1MN84 G5EFP5 G5EGL5 O17552 O61739 Q18255 Q19309 Q4TTB2 Q8MQG4 Q9TXT7 Q9U2D4	B0024.15 B0205.4 BE10.3 C05E4.15 C27D9.1 CEFT-4 CELE_F10E7.1 CELE_F53A2.11 CELE_F53C3.11 CELE_T05A7.11 CELE_T05A7.13 CELE_Y47D3A.1 fut-3 pha-1 pha1	Caenorhabditis elegans	G39211DH G81971FM G90387AM G98173LG
Syndecan interactions	BMP-like protein unc-129 Dauer larva development regulatory growth factor daf-7 Integrin alpha ina-1 Integrin alpha pat-2 Integrin beta pat-3 Probable syndecan Protein dbl-1 Protein kinase C-like 2 Protein let-756 Uncharacterized integrin beta-like protein C05D9.3	G5EBY8 G5EEL5 P34446 P50605 P90980 P92172 Q03600 Q11184 Q27874 Q9GYK2	C05D9.3 cet-1 daf-7 dbl-1 ina-1 kin-11 let-756 pat-2 pat-3 pkc-2 sdn-1 unc-129	Caenorhabditis elegans
Dectin-2 family	C-type lectin domain-containing protein 87 C-type lectin domain-containing protein 88 C-type lectin domain-containing protein 91 C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Calcineurin-interacting protein 2 EGF-like domain-containing protein EGF-like domain-containing protein	D3KFV8 H2KZ07 O18076 O45275 P91214 Q18821 Q1ZXU1 Q20665 Q21146 Q86NG3 Q94417 Q9N4W5 Q9U2D6 Q9XUF9 Q9XVS3 Q9XVT9 Q9XWC4 Q9XX56	C49C3.4 CELE_F52E1.2 CELE_Y38H6C.8 clec-149 clec-196 clec-199 clec-202 clec-204 clec-224 clec-266 clec-45 clec-47 clec-86 clec-87 clec-88 clec-91 cnp-2 cpg-5 cpg-6 paml-1	Caenorhabditis elegans
PKR-mediated signaling	ATP-dependent RNA helicase A Cyclin-dependent kinase 1 DRBM domain-containing protein DRBM domain-containing protein DZF domain-containing protein DZF domain-containing protein Dual specificity mitogen-activated protein kinase kinase jkk-1 Dual specificity mitogen-activated protein kinase kinase mek-1 Dual specificity mitogen-activated protein kinase kinase sek-1 E3 ubiquitin-protein ligase ari-1.1 Eukaryotic translation initiation factor 2-alpha kinase pek-1 HECT domain-containing protein J domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Polyubiquitin-A Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein STE20-related kinase adapter protein strd-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Sphingosine kinase 1 Ubiquitin-conjugating enzyme E2 ubc-18 Ubiquitin-like domain-containing protein X-linked retinitis pigmentosa GTPase regulator homolog mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase	D3YT30 E9RKC7 G5EBF5 G5ECN5 G5EDF7 G5EDT6 G5EGK8 O01965 O18178 O44820 O62349 P0CG71 P34556 P91189 Q09543 Q18425 Q19192 Q20977 Q21307 Q21633 Q22307 Q58AU7 Q58AU8 Q5DX34 Q8MPS3 Q95PX0 Q9BL11 Q9NAD6 Q9TYV7 Q9XWJ9	CELE_F52C6.3 CELE_R11H6.5 CELE_T12G3.2 ari-1.1 cdk-1 dnj-7 dus-2 glo-4 herc-1 jkk-1 let-92 mek-1 mek-5 ncc-1 nck-1 paa-1 pek-1 pptr-1 rde-4 rha-1 sek-1 sek-3 sek-4 sek-5 sphk-1 sta-1 sta-2 stat-b strd-1 tag-274 ubc-18 ubia ubq-1 zfr-1	Caenorhabditis elegans
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	High mobility group protein hmg-12 Histone H1.3 Intermediate filament protein ifa-1 Intermediate filament protein ifa-2 Intermediate filament protein ifa-3 Intermediate filament protein ifa-4 Intermediate filament protein ifb-1 Intermediate filament protein ifb-2 Intermediate filament protein ifc-1 Intermediate filament protein ifc-2 Intermediate filament protein ifd-1 Intermediate filament protein ifd-2 Intermediate filament protein ifp-1 Lamin-1 Probable histone chaperone asf-1 Protein HIRA Pry-1 Interacting and CABIN1 Domain containing	A0A0K3AUI7 G5EDQ2 O02365 O45168 P90900 P90901 Q09501 Q09589 Q19286 Q19289 Q19326 Q19743 Q19782 Q21065 Q21067 Q21443 Q86DC6	asf-1 hil-3 hira-1 hmg-12 hmg-I-beta ifa-1 ifa-2 ifa-3 ifa-4 ifb-1 ifb-2 ifc-1 ifc-2 ifd-1 ifd-2 ifp-1 lam-1 lmn-1 mua-6 picd-1 unc-85	Caenorhabditis elegans
GRB2:SOS provides linkage to MAPK signaling for Integrins	Abnormal cell migration protein 10 FERM domain-containing protein Fibronectin type-III domain-containing protein Inactive tyrosine-protein kinase kin-32 Integrin alpha pat-2 Integrin beta pat-3 Ras-related protein Rap-1 Sex muscle abnormal protein 5 Son of sevenless homolog Tyrosine protein-kinase src-1 Uncharacterized integrin beta-like protein C05D9.3	G5EE56 G5EGK1 P29355 P34400 P34446 Q18096 Q18246 Q27874 Q95YD4 Q9GYK2 Q9N5D3	C05D9.3 C18E9.7 kin-32 let-341 mig-10 pat-2 pat-3 rap-1 sem-5 sos-1 src-1 tln-1	Caenorhabditis elegans
EGFR Transactivation by Gastrin	MMP-like protein Matrix metalloproteinase-A Matrix metalloproteinase-B Matrix metalloproteinase-C Peptidase metallopeptidase domain-containing protein Protein kinase C-like 2 Ras protein let-60 Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5 Son of sevenless homolog Uncharacterized protein	G5EBU3 G5ECC4 G5EGM1 O17913 O44836 P22981 P24348 P29355 P90980 Q21182 Q9N5D3	CELE_K03B8.6 kin-11 kin-7 let-23 let-341 let-60 lin-34 pkc-2 sem-5 sos-1 zmp-1 zmp-2 zmp-3 zmp-5 zmp-6	Caenorhabditis elegans
Nuclear signaling by ERBB4	Gamma-secretase subunit aph-1 Gamma-secretase subunit pen-2 NAD(P)-binding protein Nicastrin Presenilin sel-12 Protein kinase domain-containing protein Receptor tyrosine-protein kinase let-23 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Tyrosine protein-kinase src-1 Yes-associated protein homolog 1	D3YT30 G5EE56 O45876 P24348 P52166 Q19062 Q19404 Q20977 Q23316 Q9NAD6 Q9U357	CELE_T12G3.2 aph-1 aph-2 dhs-7 kin-7 let-23 pen-1 pen-2 sel-12 src-1 sta-1 sta-2 stat-b yap-1	Caenorhabditis elegans
Phase I - Functionalization of compounds	3-ketosteroid oxygenase AB hydrolase-1 domain-containing protein Aldehyde dehydrogenase Aldehyde dehydrogenase Alpha/beta hydrolase fold-3 domain-containing protein CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Cytochrome b5 heme-binding domain-containing protein Cytochrome b5 heme-binding domain-containing protein Epoxide hydrolase Epoxide hydrolase Gut esterase 1 MOSC domain-containing protein MOSC domain-containing protein MOSC domain-containing protein Probable cytochrome P450 CYP36A1 Probable cytochrome P450 cyp-35D1	A0A0M7RF98 A0A1C3NSL8 A0A486WWU7 A4UVK7 G5ECD0 G5EDJ7 G5EE22 H2KY69 H2KYS3 H2L0K7 H9G2Y9 O01302 O02627 O02628 O02641 O16220 O16362 O16482 O16670 O16671 O16673 O44555 O44649 O44650 O44651 O44652 O44655 O44656 O44657 O44658 O44704 O44706 O45364 O45394 O45659 O61204 O61935 O62377 O62378 P90771 P91321 P92016 Q04457 Q19839 Q20315 Q20976 Q21266 Q22008 Q23068 Q23268 Q27465 Q27470 Q27471 Q27482 Q27499 Q4LDP0 Q8MQ23 Q93315 Q965T7 Q9N4Q4 Q9N5I1 Q9TZ58 Q9XW75 U4PC34	C45B11.6 CELE_F22B8.7 CELE_F53E10.1 CELE_F56A11.5 CELE_F58B4.2 CELE_K01A2.5 CELE_W01A11.1 alh-4 alh-5 cest-1 cest-1.1 cest-1.2 cest-12 cest-13 cest-16 cest-17 cest-19 cest-2.1 cest-2.2 cest-2.3 cest-24 cest-26 cyp-23A1 cyp-23a1 cyp-33A1 cyp-33B1 cyp-33C1 cyp-33C11 cyp-33C12 cyp-33C2 cyp-33C3 cyp-33C4 cyp-33C5 cyp-33C6 cyp-33C7 cyp-33C8 cyp-33C9 cyp-33D1 cyp-33D3 cyp-33E1 cyp-33E2 cyp-33E3 cyp-33a1 cyp-33b1 cyp-33c1 cyp-33c11 cyp-33c12 cyp-33c2 cyp-33c3 cyp-33c4 cyp-33c5 cyp-33c6 cyp-33c7 cyp-33c8 cyp-33c9 cyp-33d1 cyp-33d3 cyp-33e1 cyp-33e2 cyp-33e3 cyp-34A1 cyp-34A10 cyp-34A2 cyp-34A5 cyp-34A6 cyp-34A7 cyp-34A8 cyp-34A9 cyp-34a1 cyp-34a10 cyp-34a2 cyp-34a4 cyp-34a5 cyp-34a6 cyp-34a7 cyp-34a8 cyp-34a9 cyp-35A1 cyp-35A2 cyp-35A3 cyp-35A4 cyp-35A5 cyp-35B1 cyp-35B2 cyp-35B3 cyp-35C1 cyp-35a1 cyp-35a2 cyp-35a3 cyp-35a4 cyp-35a5 cyp-35b1 cyp-35b2 cyp-35b3 cyp-35c1 cyp-35d1 cyp-36A1 cyp36a1 cytb-5.1 dach-1 daf-9 ges-1 trcs-1	Caenorhabditis elegans
Apoptotic cleavage of cell adhesion proteins	Beta-catenin-like protein hmp-2 Cadherin-4 Cell death protein 3 Juxtamembrane domain-associated catenin OCEL domain-containing protein Tight junction protein ZO-1	O44326 P42573 Q19319 Q8I103 Q9N554 Q9U308	cdh-4 ced-3 ell-1 hmp-2 jac-1 zoo-1	Caenorhabditis elegans
FGFR2c ligand binding and activation	EGL-17 Myoblast growth factor receptor egl-15 Protein let-756	G5EEF1 Q10656 Q11184	egl-15 egl-17 let-756	Caenorhabditis elegans
Abacavir transmembrane transport	Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Organic cation transporter 1 Putative transporter B0252.3 Putative transporter B0361.11 Uncharacterized protein F23F12.3	A0A0K3AVV4 A0A0K3AWD3 A0A238UKL7 G5EDA7 G5EEI9 G5EGL6 O18247 P46499 Q09617 Q10917 Q18613 Q18655 Q18795 Q19442 Q22686 Q23501 Q4PIX1 Q7Z118 Q9BKR9 Q9U539 Q9UAW9	B0252.3 B0361.11 C06H5.6 C44C10.3 C46C2.2 CELE_F23F12.13 CELE_F45E10.2 CELE_K05F1.6 CELE_K09E9.1 CELE_K11D9.3 CELE_T08B1.1 CELE_T12B3.2 CELE_T22F7.1 CELE_Y57G11C.23 CELE_Y82E9BR.16 CELE_ZK892.3 F23F12.3/F23F12.1 oct-1 oct-2 pes-23 suex-2	Caenorhabditis elegans
Negative regulation of MAPK pathway	14-3-3-like protein 1 14-3-3-like protein 2 BRCA1-associated protein homolog 2 Dual specificity protein phosphatase lip-1 Kinase suppressor of Ras A Mitogen-activated protein kinase mpk-1 Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 Phosphatidylethanolamine-binding protein homolog F40A3.3 Polyubiquitin-A Probable serine/threonine-protein phosphatase PP2A regulatory subunit Progestin and AdipoQ Receptor family Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Raf homolog serine/threonine-protein kinase Ras protein let-60 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase par-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Serine/threonine-protein phosphatase 5 Tyrosine-protein phosphatase 1 Tyrosine-protein phosphatase domain-containing protein Tyrosine-protein phosphatase vhp-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A9UJN4 G5EFD2 G5EFV1 G5EGK8 O16264 O18178 O44514 P0CG71 P22981 P28191 P37165 P39745 P41932 P49632 P91267 Q07292 Q09543 Q10038 Q17446 Q20655 Q8MXI4 Q93344 Q95QN6 Q9NES8 Q9TW45 Q9U1V1 Q9U3L3 Q9XUJ0 Q9XX60 Q9XXC0 V6CIV8	C49C3.10 CELE_F21F3.2 CELE_W09H1.1 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 F40A3.3 brap-2 ftt-1 ftt-2 gska-3 gskl-2 ksr-1 let-60 let-92 lin-34 lin-45 lip-1 mpk-1 paa-1 paqr-3 par-1 par-5 pmk-1 pmk-2 pmk-3 pph-5 pptr-1 pptr-2 ptp-1 raf-1 sur-1 ubia ubib ubl-1 ubq-1 ubq-2 vhp-1	Caenorhabditis elegans
Synaptic adhesion-like molecules	Disks large homolog 1 GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 LITAF domain-containing protein Muscle M-line assembly protein unc-89 NMDA-type ionotropic glutamate receptor NMR-2 Reticulon-like protein Tyrosine-protein phosphatase Lar-like Tyrosine-protein phosphatase domain-containing protein	A0A1T5HUM0 G5ECY0 G5EDI2 G5EEH3 G5EGQ9 O01623 O01761 P34299 Q10914 Q17697 Q21415 Q8MXV8 Q95XL1 Q9BMN8	CELE_Y54F10BM.3 dlg-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 nmr-1 nmr-2 ptp-3 ret-1 unc-89	Caenorhabditis elegans
Signaling by Hippo	14-3-3-like protein 1 14-3-3-like protein 2 Cell death protein 3 DiSHevelled related DiSHevelled related Mob1/phocein NePHronoPhthisis (Human kidney disease) homolog Protein salvador homolog 1 Segment polarity protein dishevelled homolog mig-5 Serine/threonine-protein kinase WARTS homolog Serine/threonine-protein kinase cst-1 Tight junction protein ZO-1 Yes-associated protein homolog 1 non-specific serine/threonine protein kinase	A0A0K3AUI8 G5ECP0 O45797 P41932 P42573 P91441 Q18239 Q19404 Q20186 Q20655 Q22227 Q304D8 Q8I103 Q9NB31	ced-3 cst-1 cst-2 dsh-1 dsh-2 ftt-1 ftt-2 mig-5 mob-1 nphp-4 par-5 sav-1 wts-1 yap-1 zoo-1	Caenorhabditis elegans

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