GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Bicarbonate transporters	Anion exchange protein Anion exchange protein	B3WFV9 Q58QG8	abts-1 abts-4	Caenorhabditis elegans
Glutathione conjugation	Glutathione S-Transferase Glutathione S-transferase P Glutathione S-transferase omega Glutathione S-transferase omega Glutathione S-transferase Glutathione s-transferase kappa 2 Glutathione transferase omega-1 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Probable glutathione transferase omega-2 Probable maleylacetoacetate isomerase S-formylglutathione hydrolase	D7SFI3 G5EF86 O17234 O45352 P10299 P34277 P34345 P91020 P91997 P91998 Q17568 Q18903 Q18938 Q18973 Q21274 Q21945 Q22352 Q23320 Q9NAI5 Q9U2J5	C01G5.5 C02D5.4 C07D8.6 C56G3.2 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_Y48G10A.1 CELE_ZC443.1 exc-15 gst-1 gst-11 gst-42 gst-44 gstk-2 gsto-1 gsto-2 gsto-3	Caenorhabditis elegans
Signaling by MST1	Kringle domain-containing protein Protein kinase domain-containing protein Tyrosine-protein kinase receptor svh-2	H2KZU7 P91823 Q9XVQ7	CELE_F11E6.8 CELE_T22A3.6 svh-2	Caenorhabditis elegans
Cyclin A:Cdk2-associated events at S phase entry	BRCT domain-containing protein Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor G2/mitotic-specific cyclin-A1 GNAT family N-acetyltransferase M-phase inducer phosphatase cdc-25.1 M-phase inducer phosphatase cdc-25.2 M-phase inducer phosphatase cdc-25.3 M-phase inducer phosphatase Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2	A0A131MD44 G5EEJ2 O44552 O44628 O61847 P30634 P34638 Q17941 Q21762 Q22319 Q9XTG7	CELE_T07F10.5 CELE_T24A6.1 akt-1 akt-2 cdc-25.1 cdc-25.2 cdc-25.3 cdc-25.4 cdk-2 cki-2 cya-1	Caenorhabditis elegans
Highly calcium permeable nicotinic acetylcholine receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Proton-gated ion channel subunit pbo-6	G5EDF1 P48181 P48182 Q19351 Q23022 Q23355 Q27218 Q93149 Q93329 Q9N4M3 Q9N587	acr-12 acr-2 acr-3 acr-6 acr-8 lev-1 lev-7 lev-8 lgc-3 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Keratan sulfate degradation	Beta-galactosidase Beta-hexosaminidase A Glycoside hydrolase 35 catalytic domain-containing protein	O76632 Q22492 Q27526	bgal-1 bgal-2 hex-1	Caenorhabditis elegans	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	CED-5 Cell death abnormality protein 12 Cell death abnormality protein 2 Protein kinase domain-containing protein Protein nipi-4 Ras-like GTP-binding protein rhoA Ras-related protein ced-10 Rho-GAP domain-containing protein Tyrosine-protein kinase	A0A4V0IL59 G5EEN3 O16262 O45611 Q03206 Q22038 Q8STE5 Q9N3S5 Q9NHC3	CELE_Y47G6A.5 ced-10 ced-12 ced-2 ced-5 nipi-4 rac-1 rga-5 rho-1 rhoa trk-1	Caenorhabditis elegans
Smooth Muscle Contraction	Aldehyde dehydrogenase domain-containing protein EF-hand domain-containing protein EF-hand domain-containing protein EF-hand domain-containing protein FERM domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Myosin regulatory light chain 1 Myosin regulatory light chain 2 Myosin regulatory light chain Myosin, essential light chain Myosin-11 Myosin-11 Myosin-2 essential light chain SH3 domain-containing protein Sorbin and SH3 domain-containing protein 1 homolog Tropomodulin Tropomodulin Tropomyosin isoforms a/b/d/f Uncharacterized integrin beta-like protein C05D9.3 Vinculin	G5EBY3 G5EC32 G5EGK1 O01479 P19625 P19626 P19826 P34446 P53014 Q09510 Q18501 Q20238 Q20641 Q20780 Q21201 Q22866 Q27874 Q69Z12 Q8I7M7 Q9GYK2 Q9XVI9	C05D9.3 C36E8.4 alh-1 cal-7 deb-1 lev-11 mlc-1 mlc-2 mlc-3 mlc-4 mlc-5 mlc-6 mlc-7 nmy-1 nmy-2 pat-2 pat-3 sorb-1 tln-1 tmd-1 tmd-2 tmy-1 unc-94	Caenorhabditis elegans
Unblocking of NMDA receptors, glutamate binding and activation	Alpha-actinin, sarcomeric Calcium/calmodulin-dependent protein kinase type II Disks large homolog 1 EF-hand domain-containing protein GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 LITAF domain-containing protein NMDA-type ionotropic glutamate receptor NMR-2 Protein lap1	A0A1T5HUM0 G5ECY0 G5EEH3 G5EGQ9 O01623 O61967 O62305 P34299 Q10914 Q17697 Q18136 Q21415 Q23158 Q8MXV8	atn-1 cal-5 dlg-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 let-413 nmr-1 nmr-2 unc-43	Caenorhabditis elegans
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Kringle domain-containing protein Myoblast growth factor receptor egl-15 PIPK domain-containing protein PIPK domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Ras-related protein Rab-18 Ras-related protein ced-10 Ras-related protein rac-2 Receptor tyrosine-protein kinase let-23 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Sex muscle abnormal protein 5 Striatin N-terminal domain-containing protein Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2	A0A1I6CMA1 A0A486WY88 A9UJN4 G5EDP9 G5EE56 G5EEF1 G5EFK8 G5EGK8 H2KZU7 O01759 O18178 O44191 P24348 P29355 P91823 Q03206 Q09543 Q10656 Q11184 Q17941 Q18758 Q21046 Q94124 Q94125 Q95ZV7 Q9BL44 Q9BL73 Q9N413 Q9TZA0 Q9XTG7 Q9XVQ7	CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_T22A3.6 CELE_Y71H2AM.12 aap-1 age-1 akt-1 akt-2 cash-1 ced-10 ddr-2 egl-15 egl-17 kin-36 kin-7 klo-1 klo-2 let-23 let-756 let-92 paa-1 ppk-1 ppk-2 pptr-1 pptr-2 pvf-1 rac-1 rac-2 rme-2 sem-5 src-1 svh-2 svh-4	Caenorhabditis elegans
Platelet homeostasis	1-alkyl-2-acetylglycerophosphocholine esterase Platelet-activating factor acetylhydrolase homolog 2	G5EGT1 Q22943	paf-1 paf-2	Caenorhabditis elegans
O-linked glycosylation of mucins	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 C-type lectin domain-containing protein Calcineurin-interacting protein 2 Core-2/I-Branching enzyme EGF-like domain-containing protein EGF-like domain-containing protein GLY-16 GLYcosylation related GLYcosylation related Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 N-acetylgalactosaminide beta-1,3-galactosyltransferase N-acetylgalactosaminide beta-1,3-galactosyltransferase N-acetylgalactosaminide beta-1,3-galactosyltransferase N-acetylgalactosaminide beta-1,3-galactosyltransferase N-acetylgalactosaminide beta-1,3-galactosyltransferase N-acetylgalactosaminide beta-1,3-galactosyltransferase N-acetylgalactosaminide beta-1,3-galactosyltransferase N-acetylgalactosaminide beta-1,3-galactosyltransferase Polypeptide N-acetylgalactosaminyltransferase 3 Polypeptide N-acetylgalactosaminyltransferase 4 Probable N-acetylgalactosaminyltransferase 6 Probable N-acetylgalactosaminyltransferase 7 Probable N-acetylgalactosaminyltransferase 8 Probable N-acetylgalactosaminyltransferase 9 Putative polypeptide N-acetylgalactosaminyltransferase 10 Putative polypeptide N-acetylgalactosaminyltransferase 11 Uncharacterized protein F37A4.3	G5EBK7 G5ECK8 G5ECT3 G5EDP7 G5EEZ8 O02315 O16535 O17053 O17747 O18184 O44563 O45293 O45579 O45947 O61394 O61397 P34678 P41881 Q18515 Q19730 Q22900 Q7K755 Q8I136 Q9U2C4 Q9U2D6 Q9XUF9 Q9XWC4	C02H6.1 C16D9.6 C17A2.3 C38H2.2 C49C3.4 CELE_E03H4.3 CELE_F56H6.1 CELE_W09D10.5 CELE_Y38C1AB.1 F37A4.3 bus-4 cnp-2 gly-1 gly-10 gly-11 gly-15 gly-16 gly-17 gly-18 gly-19 gly-3 gly-4 gly-6 gly-7 gly-8 gly-9 paml-1	Caenorhabditis elegans
Phase 2 - plateau phase	Guanylate kinase/L-type calcium channel beta subunit domain-containing protein SH3 domain-containing protein STarGazin (Mammalian calcium channel) homolog STarGazin (Mammalian calcium channel) homolog Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent calcium channel unc-36	A0A078BQJ0 G5EBI8 G5EDT2 O01661 P34374 Q8MQA1	STG-1 ccb-1 ccb-2 egl-19 stg-1 stg-2 unc-36 unc-72	Caenorhabditis elegans
RHOB GTPase cycle	Anillin-like protein 2 Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 CRAL-TRIO domain-containing protein Cadherin domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 DH domain-containing protein DH domain-containing protein FH2 domain-containing protein FH2 domain-containing protein Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphoinositide 3-kinase adapter subunit Probable rho GDP-dissociation inhibitor Protein ECT2 Protein kinase domain-containing protein Protein let-99 Protein vav-1 Rac GTPase-activating protein 1 Ras-like GTP-binding protein rhoA Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho guanine nucleotide exchange factor osg-1 Rho-GAP domain-containing protein Rho-associated protein kinase let-502 SH2 domain-containing protein START domain-containing protein Stomatin-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tight junction protein ZO-1 Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A4V0IKG6 A0A4V0ILM7 A5PEW5 D6VPA1 F0IWT2 G5EDP9 G5EEN8 G5EFE1 H2KY90 H2KYI7 H2KZH5 H2KZV6 O02495 O17772 O44326 O45611 O61528 P91406 P92199 Q09994 Q10953 Q17777 Q18825 Q18879 Q19479 Q19958 Q20440 Q20496 Q21341 Q21653 Q22038 Q23130 Q45FX5 Q5F4U0 Q7JP75 Q8I103 Q93332 Q94051 Q965J0 Q9U364 Q9XUS9	C07B5.4 CELE_T04C9.1 CELE_Y105E8A.25 aap-1 aex-4 ani-2 bar-1 cav-1 cav-2 cdh-10 cgef-1 cyk-1 cyk-4 daam-1 ect-2 ephx-1 gck-4 gcp-2.1 gcp-2.2 gei-1 hmp-2 hum-7 inft-2 let-502 let-99 osg-1 pes-7 pkn-1 pvl-1 rga-1 rga-5 rhgf-1 rhi-1 rho-1 rhoa ric-4 snb-1 spy-1 sto-2 tag-81 toe-2 unc-73 vang-1 vav-1 wrm-1 zoo-1	Caenorhabditis elegans
TP53 Regulates Transcription of DNA Repair Genes	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 Cyclin-T1.1 Cyclin-T1.2 Cyclin-dependent kinase 12 Cyclin-dependent kinase 7 Cyclin-like domain-containing protein DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-C FACT complex subunit SSRP1-A FACT complex subunit spt-16 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIF subunit 2 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 OCEL domain-containing protein Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable cyclin-dependent kinase 9 Putative transcription elongation factor S-II RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II transcription factor SIII p18 subunit RNA polymerase Rpb4/RPC9 core domain-containing protein Transcription elongation factor B polypeptide 3 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha	G5ECR7 G5EFV5 K8F7X5 O02092 O17245 O17869 O44499 P16356 P34424 P34425 P34567 P41848 P46551 P52652 Q09413 Q09645 Q10578 Q17558 Q17684 Q19826 Q21338 Q8MYM8 Q93338 Q95PZ4 Q95QG8 Q965S0 Q9BKS1 Q9GR61 Q9N390 Q9N3C9 Q9N3L2 Q9N554 Q9N5K2 Q9N5R9 Q9TVL3 Q9TZ93 Q9U3I0 Q9XVH6	3L686 T24H10.1 ama-1 ccnk-1 cdk-12 cdk-7 cdk-9 cdtl-7 cit-1.1 cit-1.2 elb-1 elc-1 ell-1 fcp-1 gtf-2F1 gtf-2F2 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2f1 gtf-2f2 gtf-2h1 gtf-2h3 hmg-4 mnat-1 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 spt-16 spt-4 spt-5 tceb-3 xpb-1 xpd-1	Caenorhabditis elegans
Autodegradation of the E3 ubiquitin ligase COP1	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 RING-type domain-containing protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P37165 P46502 P49632 P90868 P91477 Q04908 Q10920 Q17971 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q27488 Q95005 Q95008 Q95PZ7 Q965F9 Q966I8 Q9GZH5 Q9N599 Q9XTT9 Q9XUV0	C14C10.5 CELE_F35G12.12 par-2 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
SRP-dependent cotranslational protein targeting to membrane	60S ribosomal protein L29 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23B Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5B Large ribosomal subunit protein uL6 Plectin/S10 N-terminal domain-containing protein Probable signal recognition particle 19 kDa protein Ribosomal Protein, Small subunit Ribosomal protein L37 Signal recognition particle 14 kDa protein Signal recognition particle 54 kDa protein Signal recognition particle 9 kDa protein Signal recognition particle subunit SRP68 Signal recognition particle subunit SRP72 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS9 Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein	G4S0D4 G5EE80 O01504 O01692 O01802 O01868 O01869 O02056 O02639 O16927 O17218 O17570 O18240 O18650 O44480 O45226 O45499 O45946 O61749 O62388 P34334 P34642 P34662 P37165 P46769 P47991 P48150 P48152 P48154 P48156 P48158 P48166 P49041 P49180 P49181 P49196 P49197 P49405 P50880 P51403 P51404 P52814 P52819 P52821 P61866 P90983 P91053 P91055 P91128 P91240 P91374 P91913 P91914 Q09533 Q19162 Q19869 Q19877 Q1XFY9 Q20206 Q20228 Q20647 Q20822 Q21930 Q22054 Q22716 Q23312 Q27389 Q8WQA8 Q93572 Q95Y04 Q95Y90 Q966C6 Q9BKU5 Q9BL19 Q9N3X2 Q9N4I4 Q9NEN6 Q9TXP0 Q9U2A8 Q9U332 Q9XVE9 Q9XVF7 Q9XVP0 Q9XWS4	C16C8.14 C16C8.16 C16C8.20 C37A2.7 CELE_F21D5.7 CELE_W01D2.1 CELE_Y37E3.8 F25G6.8 F37F2.2 ZK512.4 rla-0 rla-1 rpa-0 rpa-1 rpl-1 rpl-10 rpl-10a rpl-11.2 rpl-12 rpl-13 rpl-14 rpl-15 rpl-16 rpl-17 rpl-18 rpl-19 rpl-2 rpl-20 rpl-21 rpl-22 rpl-23 rpl-24.1 rpl-25.2 rpl-26 rpl-27 rpl-28 rpl-29 rpl-3 rpl-30 rpl-31 rpl-32 rpl-33 rpl-35 rpl-36 rpl-36.A rpl-37a rpl-38 rpl-39 rpl-4 rpl-41 rpl-43 rpl-5 rpl-6 rpl-7 rpl-7A rpl-8 rpl-9 rps-0 rps-1 rps-10 rps-11 rps-12 rps-13 rps-14 rps-15 rps-16 rps-17 rps-18 rps-19 rps-2 rps-20 rps-21 rps-22 rps-23 rps-24 rps-25 rps-26 rps-27 rps-28 rps-29 rps-3 rps-4 rps-5 rps-6 rps-7 rps-8 rps-9 srpa-68 srpa-72 ubl-1	Caenorhabditis elegans
RHO GTPases Activate WASPs and WAVEs	Actin-1 Actin-2 Actin-3 Actin-4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog Inactive tyrosine-protein kinase kin-32 Membrane-associated protein gex-3 Mitogen-activated protein kinase mpk-1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Probable actin-related protein 2/3 complex subunit 2 Probable actin-related protein 2/3 complex subunit 3 Probable actin-related protein 2/3 complex subunit 4 Protein BRICK1 Ras-related protein ced-10 SH3 domain-containing protein SPIN90/Ldb17 leucine-rich domain-containing protein Sex muscle abnormal protein 5 Tyrosine-protein kinase abl-1 WASH complex subunit homolog 1 Wiskott-Aldrich syndrome protein family member	A0A3P6PCS5 A5Z2X2 O18195 O44518 O61861 P03949 P0DM41 P0DM42 P10984 P10986 P29355 P39745 P53489 P55163 P58798 Q03206 Q05062 Q10929 Q8WTM6 Q95PX0 Q95YD4 Q9N372 Q9N4I0 Q9XVK6 Q9XWV3	CELE_Y55F3AM.5 CELE_Y57G11C.1147 abi-1 abl-1 act-1 act-2 act-3 act-4 arp-2 arx-1 arx-2 arx-3 arx-4 arx-5 arx-6 arx-7 cdc-42 ced-10 ddl-2 gex-2 gex-3 kin-32 mpk-1 nck-1 rac-1 sem-5 sur-1 wve-1	Caenorhabditis elegans
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIF subunit 2 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 HTH TFE/IIEalpha-type domain-containing protein PHD-type domain-containing protein Prion-like-(Q/N-rich)-domain-bearing protein Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 RNA polymerase Rpb4/RPC9 core domain-containing protein RNA-binding protein FUS TAFII28-like protein domain-containing protein TAFII55 protein conserved region domain-containing protein TAFII55 protein conserved region domain-containing protein TATA-box-binding protein Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor IIF subunit alpha Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 9	E9P861 G5EF68 G5EFV5 G5EG47 G5EG49 G5EGM3 K8F7X5 O02092 O16991 O17245 O44499 O44625 O45784 O61707 P16356 P32085 P34567 Q09645 Q10578 Q17558 Q17684 Q17957 Q18265 Q19826 Q20361 Q20788 Q8MYM8 Q93338 Q95PZ4 Q95ZS0 Q965S0 Q9GR61 Q9GZI6 Q9N390 Q9N3C9 Q9N3L2 Q9N5K2 Q9NEW8 Q9NEX2 Q9TYN3 Q9U226 Q9U3I0 Q9XVH6	TFIIE-alpha TFIIE-beta ama-1 cdk-7 fust-1 gtf-2A2 gtf-2E1 gtf-2E2 gtf-2F1 gtf-2F2 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2e1 gtf-2e2 gtf-2f1 gtf-2f2 gtf-2h1 gtf-2h3 mnat-1 pqn-51 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 taf-1 taf-10 taf-11 taf-11.3 taf-12 taf-13 taf-2 taf-3 taf-4 taf-5 taf-6.1 taf-7.1 taf-7.2 taf-9 tbp tbp-1 ttb-1 xpb-1 xpd-1	Caenorhabditis elegans
MAP2K and MAPK activation	14-3-3-like protein 1 14-3-3-like protein 2 Abnormal cell migration protein 10 Beta-arrestin arr-1 Calponin-homology (CH) domain-containing protein Connector enhancer of kinase suppressor of ras Dual specificity mitogen-activated protein kinase kinase mek-2 FERM domain-containing protein Fibronectin type-III domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Interleukin cytokine receptor-related protein 2 Kinase suppressor of Ras A Kinase suppressor of Ras B Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Mitogen-activated protein kinase mpk-1 Phosphatidylethanolamine-binding protein homolog F40A3.3 Raf homolog serine/threonine-protein kinase Ragulator complex protein LAMTOR2 homolog Ras protein let-60 Ras-related protein Rap-1 Serine/threonine-protein kinase par-1 Tyrosine protein-kinase src-1 Tyrosine-protein kinase csk-1 Uncharacterized integrin beta-like protein C05D9.3 Vinculin WD repeat domain-containing protein 83	G5ECJ6 G5EDA5 G5EE56 G5EEW9 G5EFD2 G5EGK1 O16264 O17772 P19826 P22981 P34400 P34446 P39745 P41932 P51485 Q07292 Q10128 Q10664 Q18096 Q18246 Q19986 Q20655 Q27874 Q8WQG5 Q9GYK2 Q9N2U6 Q9TW45	C05D9.3 C18E9.7 F40A3.3 arr-1 cnk-1 csk-1 deb-1 ftt-1 ftt-2 ilcr-2 ksr-1 ksr-2 let-60 lin-34 lin-45 lmtr-2 lmtr-3 mek-2 mig-10 mpk-1 par-1 par-5 pat-2 pat-3 pes-7 raf-1 rap-1 src-1 sur-1 tln-1 wdr-83	Caenorhabditis elegans
Ion transport by P-type ATPases	Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II Cation-transporting ATPase catp-5 Cation-transporting ATPase EF-hand domain-containing protein P-type Cu(+) transporter Phospholipid-transporting ATPase tat-1 Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Plasma membrane calcium-transporting ATPase mca-1 Probable cation-transporting ATPase W08D2.5 Probable manganese-transporting ATPase catp-8 Probable phospholipid-transporting ATPase tat-5	G5EBH1 G5EDU1 G5EE14 G5EEK8 G5EFR6 O18182 O62305 P90747 P91203 Q18136 Q21286 Q27533 Q7JPE3 Q95XP5 Q9N323 Q9TYP9 Q9U280 U4PBV8	W08D2.5 cal-5 catp-5 catp-7 catp-8 cua-1 mca-1 mca-2 mca-3 mca-4 pmr-1 sca-1 tat-1 tat-2 tat-3 tat-4 tat-5 tat-6 unc-43	Caenorhabditis elegans
N-Glycan antennae elongation	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Q9NDH7	gly-2	Caenorhabditis elegans
Stimuli-sensing channels	Acid-sensing ion channel 1-like Acid-sensing ion channel 1 Amiloride-sensitive sodium channel Amiloride-sensitive sodium channel Anoctamin Band 7 domain-containing protein Cation/H+ exchanger domain-containing protein Cation/H+ exchanger domain-containing protein Cation/H+ exchanger domain-containing protein Chloride channel protein clh-3 Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Coelomocyte uptake defective protein 15 DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Linked to Mechanosensation DEgenerin Linked to Mechanosensation Degenerin deg-1 Degenerin del-1 Degenerin mec-10 Degenerin mec-4 Degenerin unc-8 Degenerin-like protein asic-1 Degenerin-like protein asic-2 Degenerin-like protein del-10 Degenerin-like protein unc-105 E3 ubiquitin-protein ligase wwp-1 E3 ubiquitin-protein ligase EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein FLR-1 Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Polyubiquitin-A Protein tweety homolog 1 Raf homolog serine/threonine-protein kinase Serine/threonine-protein kinase sgk-1 Stomatin-1 Stomatin-2 Stomatin-3 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized transporter slc-17.2 Uncharacterized transporter slc-17.3	A0A061ACQ8 G3MU02 G5EC75 G5EFH3 G5EFS0 G5EG93 G5EGI5 G5EGT4 H2KYN8 H2KZQ1 H2L0J1 H2L2L3 O01537 O01635 O01664 O44130 O45402 P0CG71 P24585 P24612 P34272 P34886 P37165 P49632 P91100 P91102 P91103 P91835 Q03567 Q07292 Q09274 Q09322 Q10025 Q10048 Q18077 Q18651 Q19038 Q19200 Q19777 Q19958 Q20273 Q20332 Q20657 Q20852 Q21974 Q22851 Q22970 Q23514 Q23576 Q2PJ68 Q7YZV6 Q8I4F6 Q8MPW0 Q93205 Q93597 Q9BMK9 Q9N2Z7 Q9U1T8 Q9U1T9 Q9XTS9 Q9XU88	C38C10.2 CELE_F41E7.2 CELE_Y92H12A.2 acd-1 acd-2 acd-3 acd-4 acd-5 anoh-2 asic-1 asic-2 cima-1 clc-3 clh-2 clh-3 clh-4 clh-5 clh-6 cup-15 deg-1 degt-1 del-1 del-10 del-3 del-4 del-5 del-6 del-7 del-8 del-9 delm-1 delm-2 egas-1 egas-2 egas-3 egas-4 flr-1 lin-45 mec-10 mec-13 mec-4 raf-1 sgk-1 slc-17.1 slc-17.3 slc-17.4 slc-17.5 slc-17.6 slc-17.7 slc-17.8 slc-17.9 slc-9B.1 slc-9B.2 slc-9b.1 slc-9b.2 sto-1 sto-2 sto-3 sto-5 ttyh-1 ubia ubib ubl-1 ubq-1 ubq-2 unc-105 unc-8 wwp-1	Caenorhabditis elegans
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Aminopeptidase ltah-1.1 Gamma-glutamyltransferase Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Multidrug resistance-associated protein 1	A0A486WVP7 B5BM47 G5EFT4 H2L030 H2L0B7 O18256 Q3S1M2 Q9N5V4	C53D5.5 CELE_H14N18.4 CELE_T03D8.6 CELE_T19H12.6 CELE_Y7A9A.1 CELE_Y97E10AR.2 ltah-1.1 mrp-1	Caenorhabditis elegans
Transferrin endocytosis and recycling	CUP-5L Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit S1 V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q22494 Q23680 Q8T666 Q95X44 Q95YD5 Q9N5A0 Q9TYW1 Q9XW92 Q9XXU9	cup-5 fus-1 rdy-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-19 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans

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