GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **499** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Glycolysis	ATP-dependent 6-phosphofructokinase 1 ATP-dependent 6-phosphofructokinase 2 Enolase Fructose-bisphosphate aldolase 1 Fructose-bisphosphate aldolase 2 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase 1 Glyceraldehyde-3-phosphate dehydrogenase 2 Glyceraldehyde-3-phosphate dehydrogenase 3 Glyceraldehyde-3-phosphate dehydrogenase 4 Phosphoglucomutase-2 Phosphotransferase Phosphotransferase Phosphotransferase Probable ADP-dependent glucokinase Probable glucosamine-6-phosphate isomerase Probable phosphoglycerate kinase Pyruvate kinase Pyruvate kinase Triosephosphate isomerase	B7WNA0 O45934 P04970 P17329 P17330 P17331 P46563 P54216 P91427 Q10657 Q19440 Q23539 Q27483 Q27527 Q7K707 Q86S40 Q9N4A5 Q9TZL8 Q9XU15 Q9XVJ2	C50D2.7 CELE_Y43F4B.5 T03F6.3 aldo-1 aldo-2 enol-1 gpd-1 gpd-2 gpd-3 gpd-4 gpi-1 hxk-1 hxk-2 hxk-3 pfk-1.1 pfk-1.2 pgk-1 pyk-1 pyk-2 tpi-1	Caenorhabditis elegans	G58161NS
Degradation of the extracellular matrix	Cathepsin L-like Contactin rig-6 Disintegrin and metalloproteinase domain-containing protein adm-2 Disintegrin and metalloproteinase domain-containing protein unc-71 Ig-like domain-containing protein Kringle domain-containing protein MMP-like protein Matrix metalloproteinase-A Matrix metalloproteinase-B Matrix metalloproteinase-C Peptidase M12B domain-containing protein Peptidase metallopeptidase domain-containing protein Titin homolog Uncharacterized protein Zinc metalloproteinase nas-39	C6KRM7 G4SLH0 G5EBU3 G5ECC4 G5EDW5 G5EFD5 G5EGM1 H2KZ60 O17913 O44836 O45734 P91823 Q20176 Q21182 Q9N5X7	CELE_K03B8.6 CELE_T22A3.6 adm-1 adm-2 cpl-1 nas-39 rig-5 rig-6 tag-275 ttn-1 unc-71 zmp-1 zmp-2 zmp-3 zmp-5 zmp-6	Caenorhabditis elegans
HS-GAG biosynthesis	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 GlyPicaN Heparan sulfate 2-O-sulfotransferase hst-2 Heparan-sulfate 6-O-sulfotransferase Ig-like domain-containing protein InTestinal NeureXin-like LONg Laminin G domain-containing protein Probable syndecan Sulfotransferase domain-containing protein Sulfotransferase domain-containing protein Thioredoxin domain-containing protein Titin homolog UDP-sugar transporter sqv-7	C6KRM7 G4SLH0 G5ECV3 G5EFN7 G5EGU4 O17645 O45000 P50605 Q18530 Q18779 Q22574 Q4TTA0 Q966W3 Q9TZK5	C03H12.1 CELE_T19D12.6 gpn-1 hst-1 hst-2 hst-3.1 hst-3.2 hst-6 itx-1 lon-2 rig-5 sdn-1 sqv-7 ttn-1	Caenorhabditis elegans
HS-GAG degradation	Alpha-N-acetylglucosaminidase Beta-galactosidase Beta-glucuronidase GlyPicaN Glycoside hydrolase 35 catalytic domain-containing protein Ig-like domain-containing protein InTestinal NeureXin-like LONg Laminin G domain-containing protein Probable syndecan Thioredoxin domain-containing protein Titin homolog	C6KRM7 G4SLH0 G5ECV3 G5EGU4 O45000 O76632 P50605 Q18530 Q22574 Q27526 Q95Q32 Q9NAP6	C03H12.1 CELE_K09E4.4 CELE_T19D12.6 CELE_Y105E8B.9 bgal-1 bgal-2 gpn-1 itx-1 lon-2 rig-5 sdn-1 ttn-1	Caenorhabditis elegans	G01550VL G09546QO
Laminin interactions	Ig-like domain-containing protein Integrin alpha ina-1 Integrin beta pat-3 Multiple epidermal growth factor-like domains protein 6 Titin homolog Uncharacterized integrin beta-like protein C05D9.3	C6KRM7 G4SLH0 G5EFX3 Q03600 Q27874 Q9GYK2	C05D9.3 CELE_Y64G10A.7 ina-1 pat-3 rig-5 ttn-1	Caenorhabditis elegans
Non-integrin membrane-ECM interactions	Ig-like domain-containing protein Platelet-derived growth factor (PDGF) family profile domain-containing protein Probable 5-hydroxyisourate hydrolase R09H10.3 Probable 5-hydroxyisourate hydrolase ZK697.8 Protein kinase domain-containing protein Protein let-756 Titin homolog	C6KRM7 G4SLH0 O44578 Q10915 Q11184 Q21882 Q9N413	B0252.1 R09H10.3 ZK697.8 let-756 pvf-1 rig-5 ttn-1	Caenorhabditis elegans
ECM proteoglycans	Dystroglycan 1 Fibrinogen C-terminal domain-containing protein Fibrinogen C-terminal domain-containing protein Fibrinogen C-terminal domain-containing protein Fibronectin type-III domain-containing protein Ig-like domain-containing protein InTestinal NeureXin-like Integrin alpha ina-1 Integrin alpha pat-2 Integrin beta pat-3 Laminin G domain-containing protein SPARC Titin homolog Uncharacterized integrin beta-like protein C05D9.3	C6KRM7 G4SLH0 O45000 P34446 P34714 Q03600 Q18096 Q18705 Q22574 Q22629 Q27874 Q5ZR75 Q9GYK2 Q9XXE9	C05D9.3 C18E9.7 C49C8.5 CELE_T15B7.1 CELE_T19D12.6 CELE_Y43C5A.2 dgn-1 ina-1 itx-1 ost-1 pat-2 pat-3 rig-5 sparc ttn-1	Caenorhabditis elegans
Cross-presentation of soluble exogenous antigens (endosomes)	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 C-type lectin domain-containing protein 161 C-type lectin domain-containing protein 87 C-type lectin domain-containing protein 88 C-type lectin domain-containing protein 91 C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein MPN domain-containing protein PCI domain-containing protein Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5	D3KFV8 G4RY15 H2KZ07 O16368 O17071 O17586 O18076 O44156 O45275 O61742 O61792 O62102 O76371 O76577 P34472 P46502 P90868 P91214 P91429 P91477 Q04908 Q10920 Q17450 Q17452 Q17971 Q18115 Q18787 Q18821 Q19324 Q1ZXU1 Q20058 Q20585 Q20665 Q20938 Q21146 Q22253 Q22591 Q23237 Q23449 Q27488 Q86NG3 Q94417 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N4W5 Q9N599 Q9TZ75 Q9XTT9 Q9XUL6 Q9XUL7 Q9XUV0 Q9XVE1 Q9XVS3 Q9XVT9 Q9XX56	C14C10.5 CELE_F35G12.12 CELE_F52E1.2 CELE_Y38H6C.8 clec-148 clec-149 clec-161 clec-178 clec-196 clec-199 clec-202 clec-204 clec-224 clec-266 clec-45 clec-47 clec-48 clec-49 clec-50 clec-51 clec-52 clec-53 clec-86 clec-87 clec-88 clec-89 clec-91 cpg-5 cpg-6 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6	Caenorhabditis elegans
Dectin-2 family	C-type lectin domain-containing protein 87 C-type lectin domain-containing protein 88 C-type lectin domain-containing protein 91 C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Calcineurin-interacting protein 2 EGF-like domain-containing protein EGF-like domain-containing protein	D3KFV8 H2KZ07 O18076 O45275 P91214 Q18821 Q1ZXU1 Q20665 Q21146 Q86NG3 Q94417 Q9N4W5 Q9U2D6 Q9XUF9 Q9XVS3 Q9XVT9 Q9XWC4 Q9XX56	C49C3.4 CELE_F52E1.2 CELE_Y38H6C.8 clec-149 clec-196 clec-199 clec-202 clec-204 clec-224 clec-266 clec-45 clec-47 clec-86 clec-87 clec-88 clec-91 cnp-2 cpg-5 cpg-6 paml-1	Caenorhabditis elegans
Asparagine N-linked glycosylation	C-type lectin domain-containing protein 87 C-type lectin domain-containing protein 88 C-type lectin domain-containing protein 91 C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein	D3KFV8 H2KZ07 O18076 O45275 P91214 Q18821 Q1ZXU1 Q20665 Q21146 Q86NG3 Q94417 Q9N4W5 Q9XVS3 Q9XVT9 Q9XX56	CELE_F52E1.2 CELE_Y38H6C.8 clec-149 clec-196 clec-199 clec-202 clec-204 clec-224 clec-266 clec-45 clec-47 clec-86 clec-87 clec-88 clec-91 cpg-5 cpg-6	Caenorhabditis elegans
PKR-mediated signaling	ATP-dependent RNA helicase A Cyclin-dependent kinase 1 DRBM domain-containing protein DRBM domain-containing protein DZF domain-containing protein DZF domain-containing protein Dual specificity mitogen-activated protein kinase kinase jkk-1 Dual specificity mitogen-activated protein kinase kinase mek-1 Dual specificity mitogen-activated protein kinase kinase sek-1 E3 ubiquitin-protein ligase ari-1.1 Eukaryotic translation initiation factor 2-alpha kinase pek-1 HECT domain-containing protein J domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Polyubiquitin-A Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein STE20-related kinase adapter protein strd-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Sphingosine kinase 1 Ubiquitin-conjugating enzyme E2 ubc-18 Ubiquitin-like domain-containing protein X-linked retinitis pigmentosa GTPase regulator homolog mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase	D3YT30 E9RKC7 G5EBF5 G5ECN5 G5EDF7 G5EDT6 G5EGK8 O01965 O18178 O44820 O62349 P0CG71 P34556 P91189 Q09543 Q18425 Q19192 Q20977 Q21307 Q21633 Q22307 Q58AU7 Q58AU8 Q5DX34 Q8MPS3 Q95PX0 Q9BL11 Q9NAD6 Q9TYV7 Q9XWJ9	CELE_F52C6.3 CELE_R11H6.5 CELE_T12G3.2 ari-1.1 cdk-1 dnj-7 dus-2 glo-4 herc-1 jkk-1 let-92 mek-1 mek-5 ncc-1 nck-1 paa-1 pek-1 pptr-1 rde-4 rha-1 sek-1 sek-3 sek-4 sek-5 sphk-1 sta-1 sta-2 stat-b strd-1 tag-274 ubc-18 ubia ubq-1 zfr-1	Caenorhabditis elegans
Nuclear signaling by ERBB4	Gamma-secretase subunit aph-1 Gamma-secretase subunit pen-2 NAD(P)-binding protein Nicastrin Presenilin sel-12 Protein kinase domain-containing protein Receptor tyrosine-protein kinase let-23 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Tyrosine protein-kinase src-1 Yes-associated protein homolog 1	D3YT30 G5EE56 O45876 P24348 P52166 Q19062 Q19404 Q20977 Q23316 Q9NAD6 Q9U357	CELE_T12G3.2 aph-1 aph-2 dhs-7 kin-7 let-23 pen-1 pen-2 sel-12 src-1 sta-1 sta-2 stat-b yap-1	Caenorhabditis elegans
MET activates STAT3	Kringle domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Tyrosine-protein kinase receptor svh-2	D3YT30 H2KZU7 P91823 Q20977 Q9NAD6 Q9XVQ7	CELE_F11E6.8 CELE_T12G3.2 CELE_T22A3.6 sta-1 sta-2 stat-b svh-2	Caenorhabditis elegans
Interleukin-4 and Interleukin-13 signaling	Endoplasmin homolog Protein kinase domain-containing protein Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b	D3YT30 Q20977 Q22235 Q9NAD6	CELE_T12G3.2 enpl-1 sta-1 sta-2 stat-b	Caenorhabditis elegans
Interleukin-6 signaling	Fibronectin type-III domain-containing protein Protein kinase domain-containing protein Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b	D3YT30 Q20977 Q9NAD6 Q9UB28	CELE_T12G3.2 let-805 sta-1 sta-2 stat-b	Caenorhabditis elegans
Synthesis of glycosylphosphatidylinositol (GPI)	GPI ethanolamine phosphate transferase 1 GPI mannosyltransferase pigv-1 Mannosyltransferase N-acetylglucosaminylphosphatidylinositol deacetylase Phosphatidylinositol-glycan biosynthesis class W protein	D4YWC2 D6RYD7 G4SNP0 G5EDN2 O02164	PIG-B hpo-20 pigb-1 pigl-1 pign-1 pigv-1 pigw-1	Caenorhabditis elegans
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	EF-hand domain-containing protein GTP cyclohydrolase 1 feedback regulatory protein GTP cyclohydrolase 1 Heat shock protein 90 Putative 6-pyruvoyl tetrahydrobiopterin synthase Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2	D6RYD9 O02058 Q17941 Q18136 Q18688 Q19980 Q9XTG7	akt-1 akt-2 cal-5 cat-4 daf-21 gfrp-1 ptps-1	Caenorhabditis elegans
Vitamin C (ascorbate) metabolism	Cytochrome b5 heme-binding domain-containing protein Facilitated glucose transporter homolog Facilitated glucose transporter protein 1 Glutathione S-transferase omega Glutathione S-transferase omega Glutathione S-transferase Glutathione transferase omega-1 MFS domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Probable glutathione transferase omega-2 Solute carrier family 23 member 2 Solute carrier family 23 member 2 Solute carrier family 23 member 2 Solute carrier family 23 member 2 Solute carrier family 23 member 2 Solute carrier family 23 member 2	D6RYE3 D7SFI3 G5EC93 G8JZM6 O16547 O17234 O18057 O18061 O44616 O44827 O45352 O45920 P34277 P34345 Q18771 Q19376 Q20734 Q21381 Q21382 Q21385 Q23535 Q23626 Q5WRR9 Q93315 Q95QY6 Q9GPA2 Q9GYQ1 Q9NEI8 Q9TYX7 Q9U2K5 Q9XU83 Q9XVL3	C02D5.4 C03B1.13 C35A11.4 C51E3.6 CELE_F11D5.5 CELE_F11D5.7 CELE_F13B12.2 CELE_F48E3.2 CELE_F53H8.3 CELE_K08F9.1 CELE_K08H10.6 CELE_K09C4.1 CELE_K09C4.4 CELE_K09C4.5 CELE_R11E3.2 CELE_T07G12.2 CELE_T07G12.4 CELE_T07G12.5 CELE_Y37A1A.3 CELE_Y39B6A.41 CELE_Y39E4B.5 CELE_Y59E9AL.4 CELE_ZK829.9 R09B5.11 cytb-5.1 fdgt-2 fgt-1 gst-44 gsto-1 gsto-2 gsto-3 slcf-2	Caenorhabditis elegans
Glutathione conjugation	Glutathione S-Transferase Glutathione S-transferase P Glutathione S-transferase omega Glutathione S-transferase omega Glutathione S-transferase Glutathione s-transferase kappa 2 Glutathione transferase omega-1 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Probable glutathione transferase omega-2 Probable maleylacetoacetate isomerase S-formylglutathione hydrolase	D7SFI3 G5EF86 O17234 O45352 P10299 P34277 P34345 P91020 P91997 P91998 Q17568 Q18903 Q18938 Q18973 Q21274 Q21945 Q22352 Q23320 Q9NAI5 Q9U2J5	C01G5.5 C02D5.4 C07D8.6 C56G3.2 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_Y48G10A.1 CELE_ZC443.1 exc-15 gst-1 gst-11 gst-42 gst-44 gstk-2 gsto-1 gsto-2 gsto-3	Caenorhabditis elegans
Iron uptake and transport	ABC transporter domain-containing protein ABC transporter family G domain-containing protein Cullin-1 Cullin-associated NEDD8-dissociated protein 1 Cytochrome b561 domain-containing protein Cytochrome b561 domain-containing protein Cytoplasmic aconitate hydratase Ferritin Ferritin NEDD8 NRAMP-like transporter smf-1 Polyubiquitin-A Proton-coupled folate transporter Putative transmembrane ascorbate-dependent reductase CYB561 homolog Skp1-related protein SoLute Carrier family Related SoLute Carrier family Related Solute carrier family 46 member 3 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized MFS-type transporter C09D4.1	D7SFK1 G5ECU1 G5ED41 H2KZC0 O01735 O16271 O16272 O16453 P0CG71 P34465 P37165 P49632 Q17389 Q19585 Q20236 Q21434 Q23500 Q93725 Q9TYS3 Q9UAZ6 Q9XWL3	C09D4.1 CELE_F39G3.4 CELE_F39G3.5 F55H2.5 abcx-1 aco-1 cand-1 cul-1 ftn-1 ftn-2 gei-22 lin-19 ned-8 skr-1 slc-46A slc-46a slcr-46.1 slcr-46.2 slcr-46.3 smf-1 ubia ubib ubl-1 ubq-1 ubq-2 wht-5	Caenorhabditis elegans
Heme degradation	ABC transmembrane type-1 domain-containing protein ABC transporter domain-containing protein ABC transporter family G domain-containing protein Fatty acid-binding protein homolog 5 Fatty acid-binding protein homolog 6 Fatty acid-binding protein homolog 7 Fatty acid-binding protein homolog 8 Multidrug resistance protein mrp-7 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member	D7SFK1 G5EFP3 O01812 O01814 O02323 O02324 Q19048 Q19585 Q20943 Q3S1M2 Q93550 Q9U2G5 Q9XW61	CELE_F21G4.1 abcx-1 lbp-5 lbp-6 lbp-7 lbp-8 mrp-1 mrp-2 mrp-3 mrp-4 mrp-7 mrp-8 wht-5	Caenorhabditis elegans
Transcriptional regulation by small RNAs	Argonaute (Plant)-Like protein Argonaute protein wago-1 Argonaute protein wago-4 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H3-like centromeric protein hcp-3 Histone H3.3 type 1 Histone H3 Histone H3 Histone H4 Piwi domain-containing protein Piwi domain-containing protein Piwi domain-containing protein Piwi domain-containing protein Piwi-like protein ergo-1 Piwi-like protein Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Protein argonaute-2 Protein argonaute-2 Protein argonaute-2 Putative protein tag-76 RNA polymerase Rpb4/RPC9 core domain-containing protein	D9N120 G5ED77 G5EEH0 G5EES3 H2KZD5 K7ZUH9 O02092 O16720 O61931 O62275 P08898 P09588 P16356 P34470 P34681 P62784 Q10453 Q10578 Q17684 Q19826 Q21770 Q23429 Q27485 Q27511 Q93338 Q965S0 Q9GR61 Q9N3C9 Q9N585 Q9N5K2 Q9U3I0 Q9XVF1 Q9XVH6 Q9XVI3	CENP-A alg-1 alg-2 alg-3 alg-5 ama-1 csr-1 ergo-1 hcp-3 his-1 his-10 his-12 his-13 his-14 his-16 his-17 his-18 his-19 his-2 his-21 his-25 his-26 his-27 his-28 his-3 his-30 his-31 his-32 his-33 his-35 his-37 his-38 his-40 his-42 his-43 his-45 his-46 his-47 his-49 his-5 his-50 his-51 his-53 his-55 his-56 his-57 his-59 his-6 his-60 his-61 his-63 his-64 his-65 his-67 his-68 his-7 his-71 his-9 hpo-24 htas-1 htz-1 ppw-2 rde-1 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 tag-76 vsra-1 wago-1 wago-4 wago-5	Caenorhabditis elegans
NCAM signaling for neurite out-growth	Inactive tyrosine-protein kinase kin-32 Mitogen-activated protein kinase mpk-1 Putative ribosomal protein S6 kinase alpha-2 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog Spectrin alpha chain Spectrin beta chain Spectrin beta chain Tyrosine protein-kinase src-1 Tyrosine-protein phosphatase Lar-like Uncharacterized protein C50C3.2	E0AHA7 G5EE56 G5EFW3 P22981 P29355 P34367 P39745 Q18846 Q21408 Q95YD4 Q9BMN8 Q9N5D3	C50C3.2/C50C3.3 kin-32 let-341 let-60 lin-34 mpk-1 ptp-3 rskn-2 sem-5 sma-1 sos-1 spc-1 src-1 sur-1 unc-70	Caenorhabditis elegans
Signaling by EGFR	EGF-like domain-containing protein EGF-like domain-containing protein Leucine-rich repeats and immunoglobulin-like domains protein sma-10 Receptor tyrosine-protein kinase let-23 Tyrosine protein-kinase src-1 WD_REPEATS_REGION domain-containing protein	E0R7L2 G5EE56 G5EFK8 O44191 P24348 Q965M2	CELE_F14B4.1 CELE_Y111B2A.12 kin-7 let-23 rme-2 sma-10 src-1	Caenorhabditis elegans
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Alpha-1,2-mannosyltransferase algn-9 Alpha-1,3/1,6-mannosyltransferase ALG2 Chitobiosyldiphosphodolichol beta-mannosyltransferase Dol-P-Man Dol-P-Man Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase Mannose-P-dolichol utilization defect 1 protein homolog N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase UDP-N-acetylglucosamine transferase subunit ALG14 homolog UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	E5QCI3 P52887 P54002 P92012 Q09226 Q19265 Q20157 Q22797 Q23361 Q9U1Z2 U4PE03	algn-1 algn-12 algn-13 algn-14 algn-2 algn-3 algn-6 algn-7 algn-8 algn-9 hpo-16 hpo-17 mpdu-1	Caenorhabditis elegans

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