GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
SHC-related events triggered by IGF1R	Growth factor receptor-bound protein 2 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 P01346 P08025 P24062 P62994 Q5M824	Ash Grb2 Igf-1 Igf-2 Igf1 Igf1r Igf2 Shc1 Sos1	Rattus norvegicus (Norway rat)
Insulin receptor signalling cascade	Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Insulin receptor Insulin-1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 P01322 P0CE43 P15127 P62994 Q5M824	Ash Grb10 Grb2 Ins-1 Ins1 Insr Shc1 Sos1	Rattus norvegicus (Norway rat)
Signalling to RAS	Growth factor receptor-bound protein 2 SHC-transforming protein 1 SHC-transforming protein 2 SHC-transforming protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 O70142 O70143 P62994 Q5M824	Ash Grb2 Nshc Sck Shc1 Shc2 Shc3 Shcc Sos1	Rattus norvegicus (Norway rat)
EGFR Transactivation by Gastrin	GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C alpha type Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1	D4A3T0 G3V6K6 P03957 P05696 P08644 P20171 P62994 Q04970 Q06175	Ash Dtr Egfr Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Mmp3 Nras Pkca Prkca Sos1	Rattus norvegicus (Norway rat)
SOS-mediated signalling	Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 F1MAL5 P35570 P62994	Ash Grb2 Irs-1 Irs1 Irs2 Sos1	Rattus norvegicus (Norway rat)
Signal attenuation	Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin-1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 F1MAL5 P01322 P0CE43 P15127 P21708 P35570 P62994 P63086 Q5M824	Ash Erk1 Erk2 Grb10 Grb2 Ins-1 Ins1 Insr Irs-1 Irs1 Irs2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Shc1 Sos1	Rattus norvegicus (Norway rat)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Guanine nucleotide-binding protein G(olf) subunit alpha adenylate cyclase	D4A3N4 F1LQT1 M0R5U4 P21932 P26769 P26770 P38406 P40146 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Gnal	Rattus norvegicus (Norway rat)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Calmodulin-3 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	D4A3N4 F1LQT1 M0R5U4 P09456 P0DP31 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 CaMIII Calm3 Cam3 Camc Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b	Rattus norvegicus (Norway rat)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3 adenylate cyclase	D4A3N4 F1LQT1 M0R5U4 P04897 P08753 P10824 P21932 P26769 P26770 P29348 P38406 P40146 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnal Gnat-3 Gnat3	Rattus norvegicus (Norway rat)
Tight junction interactions	Junctional adhesion molecule A Par-6 family cell polarity regulator beta Par-6 family cell polarity regulator gamma Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Protein kinase C iota type	D4A2F2 E9PT71 F1M7Y5 Q6B4M5 Q9JHY1 Q9Z340	F11r Jam1 Par-6a Par3 Par6a Pard3 Pard6a Pard6b Pard6g Pkcl Prkci	Rattus norvegicus (Norway rat)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Growth factor receptor-bound protein 2 Neurotrophin-4 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A244 D4A3T0 P23363 P34131 P62994 Q63604	Ash Bdnf Frs2 Grb2 Nt4 Ntf4 Ntf5 Ntrk2 Sos1 Trkb	Rattus norvegicus (Norway rat)
LDL remodeling	Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	D4A1W8 P04785	Mtp Mttp P4hb Pdia1	Rattus norvegicus (Norway rat)
VLDL assembly	Apolipoprotein B-100 Apolipoprotein C-I Apolipoprotein C-IV Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	D4A1W8 P04785 P19939 P55797 Q7TMA5	Apob Apoc1 Apoc4 Ecl Mtp Mttp P4hb Pdia1	Rattus norvegicus (Norway rat)
Chylomicron assembly	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase Small COPII coat GTPase SAR1B	D4A1W8 G3V8D4 P02650 P02651 P04638 P04639 P04785 P06759 Q5HZY2 Q7TMA5	Apoa1 Apoa2 Apoa4 Apob Apoc2 Apoc3 Apoe Mtp Mttp P4hb Pdia1 Sar1b	Rattus norvegicus (Norway rat)
Amine ligand-binding receptors	G protein-coupled receptor 143 Trace amine-associated receptor 1 Trace amine-associated receptor 2 Trace amine-associated receptor 3 Trace amine-associated receptor 5 Trace amine-associated receptor 6 Trace amine-associated receptor 8a Trace amine-associated receptor 8c Trace amine-associated receptor 9	D4A082 Q5QD23 Q5QD24 Q5QD25 Q923X9 Q923Y0 Q923Y5 Q923Y6 Q923Y9	Gpr143 Gpr58 Ta1 Ta10 Ta11 Ta3 Ta4 Taar1 Taar2 Taar3 Taar5 Taar6 Taar8a Taar8c Taar9 Tar1 Tar10 Tar11 Tar3 Tar4 Trar1 Trar10 Trar11 Trar3 Trar4	Rattus norvegicus (Norway rat)
Presynaptic depolarization and calcium channel opening	Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2 Voltage-dependent calcium channel subunit alpha-2/delta-3	D4A055 P54282 P54283 P54287 Q02294 Q07652 Q71RJ2 Q8CFG5 Q8CFG6 Q8VGC3 Q8VHW9	Cach4 Cach5 Cach6 Cacn3 Cacna1a Cacna1b Cacna1e Cacna2d2 Cacna2d3 Cacnb1 Cacnb2 Cacnb3 Cacnb4 Cacng2 Cacng4 Cacnl1a4 Cacnl1a5 Cacnl1a6 Cacnlb1 Cacnlb2 Cacnlb3 Stg	Rattus norvegicus (Norway rat)
Chylomicron remodeling	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Lipoprotein lipase	D3ZZL5 G3V8D4 P02650 P02651 P04638 P04639 P06759 Q06000 Q7TMA5 Q9QUH3	Apoa1 Apoa2 Apoa4 Apoa5 Apob Apoc2 Apoc3 Apoe Gpihbp1 Lpl Rap3	Rattus norvegicus (Norway rat)
Zinc efflux and compartmentalization by the SLC30 family	Proton-coupled zinc antiporter SLC30A1 Proton-coupled zinc antiporter SLC30A8 Zinc transporter	D3ZY54 P0CE46 Q62720	Slc30a1 Slc30a5 Slc30a8 Znt1 Znt8	Rattus norvegicus (Norway rat)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05	Casp8 Cd14 Fadd Ly96 Plin3 Ripk1 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05 Q9Z2P5	Casp8 Cd14 Fadd Ly96 Plin3 Rip3 Ripk1 Ripk3 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Bicarbonate transporters	Adenosylhomocysteinase-like 2 Anion exchange protein 2 Anion exchange protein 3 Anion exchange protein 4 Band 3 anion transport protein Electrogenic sodium bicarbonate cotransporter 1 Electrogenic sodium bicarbonate cotransporter 4 Electroneutral sodium bicarbonate exchanger 1 Sodium bicarbonate cotransporter 3 Sodium-driven chloride bicarbonate exchanger	D3ZWL6 P23347 P23348 P23562 Q6RI88 Q6RVG2 Q80ZA5 Q8K4V2 Q9JI66 Q9R1N3	Ae1 Ae2 Ae3 Ae4 Ahcyl2 B3rp2 B3rp3 Nbc Nbc1 Nbc2 Nbc3 Nbce1 Nbcn1 Ncbe Ndcbe1 Rnbc1 Slc4a1 Slc4a10 Slc4a2 Slc4a3 Slc4a4 Slc4a5 Slc4a7 Slc4a8 Slc4a9	Rattus norvegicus (Norway rat)
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	D3ZWI0 O35776 Q8CH92 Q8CH93 Q9QYM0	Abcc5 Cemip HAS1 HAS3 Has1 Has2 Has3 LOC282821 Mrp5 RGD1305254	Rattus norvegicus (Norway rat)	G35674CY
Ligand-independent caspase activation via DCC	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Caspase-3 Caspase-9 Netrin receptor DCC	D3ZWA8 P55213 Q63155 Q9JHK1	Appl1 Casp3 Casp9 Cpp32 Dcc RNCASP9	Rattus norvegicus (Norway rat)
FGFR2b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 7 Fibroblast growth factor binding protein 3 Fibroblast growth factor receptor Fibroblast growth factor-binding protein 1 Fibroblast growth factor Fibroblast growth factor	D3ZVI0 F1LSG7 P13109 P61149 P70492 Q02195 Q8R5L9 Q8VI79 Q9QY10	FGF22 Fgf-1 Fgf-2 Fgf-7 Fgf1 Fgf10 Fgf2 Fgf22 Fgf3 Fgf5c Fgf5d Fgf7 Fgfa Fgfbp1 Fgfbp3 Fgfr2 Kgf	Rattus norvegicus (Norway rat)
Arachidonic acid metabolism	Acyltransferase Cytosolic phospholipase A2 Fatty-acid amide hydrolase 1	D3ZVA9 P50393 P97612	Awat1 Cpla2 Faah Faah1 Pla2g4 Pla2g4a	Rattus norvegicus (Norway rat)

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