GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **276 - 300** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Collagen biosynthesis and modifying enzymes	ADAM metallopeptidase with thrombospondin type 1 motif, 14 ADAM metallopeptidase with thrombospondin type 1 motif, 2 ADAM metallopeptidase with thrombospondin type 1, motif 3 Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(V) chain Collagen alpha-1(XI) chain Collagen alpha-1(XXIII) chain Collagen alpha-2(I) chain Collagen beta(1-O)galactosyltransferase 2 Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IV alpha 5 chain Collagen type IV alpha 6 chain Collagen type IX alpha 2 chain Collagen type IX alpha 3 chain Collagen type V alpha 2 chain Collagen type V alpha 3 chain Collagen type VI alpha 2 chain Collagen type VI alpha 3 chain Collagen type VI alpha 5 chain Collagen type VI alpha 6 chain Collagen type VII alpha 1 chain Collagen type VIII alpha 1 chain Collagen type VIII alpha 2 chain Collagen type X alpha 1 chain Collagen type XI alpha 2 chain Collagen type XIII alpha 1 chain Collagen type XIV alpha 1 chain Collagen type XIX alpha 1 chain Collagen type XV alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVII alpha 1 chain Collagen type XVIII alpha 1 chain Collagen type XX alpha 1 chain Collagen type XXII alpha 1 chain Collagen type XXV alpha 1 chain Collagen type XXVI alpha 1 chain Collagen type XXVIII alpha 1 chain G protein-coupled receptor 162 Metalloendopeptidase Metalloendopeptidase Metalloendopeptidase Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 Procollagen C-endopeptidase enhancer 1 Procollagen C-endopeptidase enhancer 2 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Prolyl 3-hydroxylase 2 Prolyl 4-hydroxylase subunit alpha-1 Prolyl 4-hydroxylase subunit alpha-3 Protein disulfide-isomerase Serpin H1 procollagen-proline 4-dioxygenase	A0A0G2JTX7 A0A0G2JV12 A0A0G2K069 A0A0G2K2Q8 A0A0G2K601 A0A0G2K742 A0A0G2K7A5 A0A0G2K8N4 A0A8I5ZMX2 A0A8I5ZZ86 A0A8I6AHL9 A0A8I6ASK1 A0A8I6GBI7 A0A8I6GLR1 D3Z8U5 D3Z9Z7 D3ZA74 D3ZCQ0 D3ZE04 D3ZII5 D3ZL10 D3ZN64 D3ZNT5 D3ZTE7 D3ZX71 D3ZZT9 D4AAS1 D4AC70 D4ADG9 F1LND0 F1LNH3 F1LQ00 F1LRJ1 F1M280 F1M6Q3 F1M798 F1M897 F1MA59 F7EVZ0 M0RAM0 M0RD26 O08628 P02454 P02466 P04785 P05539 P13941 P20909 P29457 P54001 Q4KLM6 Q5U367 Q63321 Q6W3E9 Q810Y4 Q811A3 Q9JI03	Adamts14 Adamts2 Adamts3 Bmp1 Cbp1 Col10a1 Col11a1 Col11a2 Col13a1 Col14a1 Col15a1 Col16a1 Col17a1 Col18a1 Col19a1 Col1a1 Col1a2 Col20a1 Col22a1 Col23a1 Col25a1 Col26a1 Col28a1 Col2a1 Col3a1 Col4a1 Col4a2 Col4a3 Col4a4 Col4a5 Col4a6 Col5a1 Col5a2 Col5a3 Col6a2 Col6a3 Col6a5 Col6a6 Col7a1 Col8a1 Col8a2 Col9a2 Col9a3 Colgalt2 Glt25d2 Gpr162 Hsp47 LOC100909752 LOC100911572 LOC687064 Leprel1 P3h2 P3h3 P4ha P4ha1 P4ha2 P4ha3 P4hb PCOLCE2 Pcolce Pcpe1 Pdia1 Plod Plod1 Plod2 Plod3 RGD1564680 Serpinh1 Tll1 Tll2	Rattus norvegicus (Norway rat)
PKR-mediated signaling	Alpha-synuclein Cellular tumor antigen p53 Cyclin-dependent kinase 1 Cytoplasmic protein DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase FA complementation group A FA complementation group B FA complementation group E FA complementation group F FA complementation group G FA complementation group L FA complementation group M FA core complex associated protein 100 FA core complex associated protein 24 Fanconi anemia core complex-associated protein 20 Fanconi anemia group C protein homolog Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 ISG15 ubiquitin-like modifier Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Microtubule-associated protein tau Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleophosmin Protein phosphatase 2 scaffold subunit A alpha RBR-type E3 ubiquitin transferase RISC-loading complex subunit TARBP2 RNA helicase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Sphingosine kinase 1 Tripartite motif-containing 25 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin/ISG15-conjugating enzyme E2 L6 mitogen-activated protein kinase kinase	A0A0G2JWL4 A0A0G2JX93 A0A0G2K7F0 A0A8I5ZNL4 A0A8I6ABZ7 A0A8I6AGX8 A0A8I6AH74 A0A8I6ANR6 B2RZ33 D3ZAU3 D3ZDI7 D3ZE71 D3ZXL1 D4A3X3 D4A5I2 D4A9N5 D4AAA5 F1M0R6 F1M286 O35870 P0DMW0 P0DMW1 P10361 P13084 P14659 P19332 P35233 P37377 P39951 P52631 P55063 P55266 P62716 P63018 P63331 Q3SWU0 Q4QQT4 Q4V8C7 Q4V8J2 Q5XI34 Q63184 Q66HG9 Q6TMG5 Q7TP98 Q91V26 Q925D6 Q9JIL3 Q9QY78 Q9R0T3	Adar Arih1 Cdc2 Cdc2a Cdk1 Cdkn1 Chuk Dhx9 Dnajc3 Dsrad Eif2ak2 Faap100 Faap20 Faap24 Facc Fanca Fancb Fancc Fance Fancf Fancg Fancl Fancm Hsc70 Hsc73 Hsp70-1 Hsp70-2 Hsp70-3 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hst70 Ikbkb Ikbkg Ikkb Ilf2 Ilf3 Ips1 Isg15 Map2k6 Mapt Mavs Mkk6 Mtapt Nck1 Nemo Npm1 P53 P58ipk Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Prkr Prkra Ptpn2 RGD1564719 Snca Sphk1 Stat1 Stat3 Stat4 Tarbp2 Tau Tp53 Trim25 Ube2l6 Visa	Rattus norvegicus (Norway rat)
Ubiquinol biosynthesis	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 4-hydroxybenzoate polyprenyltransferase, mitochondrial 5-demethoxyubiquinone hydroxylase, mitochondrial (Fragment) All trans-polyprenyl-diphosphate synthase PDSS2 Atypical kinase COQ8A, mitochondrial Atypical kinase COQ8B, mitochondrial Decaprenyl diphosphate synthase subunit 1 Ubiquinone biosynthesis O-methyltransferase, mitochondrial Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial Ubiquinone biosynthesis protein COQ9, mitochondrial	M0R6Q9 Q499N4 Q4FZU1 Q4G064 Q5BJQ0 Q5U2R1 Q63159 Q63619 Q68FT1 Q68FU7 Q6AY19	Adck3 Adck4 Cabc1 Coq2 Coq3 Coq4 Coq5 Coq6 Coq7 Coq8a Coq8b Coq9 Dlp1 LOC100364990 Pdss1 Pdss2	Rattus norvegicus (Norway rat)
Hedgehog 'off' state	Adenylate cyclase type 10 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Cytoplasmic dynein 2 heavy chain 1 G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Intraflagellar transport 140 Intraflagellar transport 52 Intraflagellar transport 88 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 57 homolog Kinesin family member 7 Kinesin-like protein Ofd1 centriole and centriolar satellite protein Patched Protein fuzzy homolog Protein inturned Protein smoothened Rpgrip1-like Suppressor of fused homolog Tectonic-like complex member MKS1 Tetratricopeptide repeat domain 21B Tubby-like protein WD repeat domain 19 WD repeat-containing protein 35 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A0G2JZL6 A0A8I5Y075 A0A8I5ZPQ6 A0A8I6A606 A0A8I6AA62 A0A8I6GBB8 A6N6J5 D3Z8G3 D4A1V1 D4A3N4 D4A9P0 D4ACE5 F1LQT1 F1LQZ3 F1LV01 F1LY69 F1M2B7 F1M5Q2 F1M656 F1M9H1 G3V6X8 M0R5U4 P09456 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 P97698 Q03343 Q04400 Q3B756 Q499Q5 Q6UY90 Q9JJ79 Q9JKU3 Q9Z286	Adcy1 Adcy10 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Dhc1b Dlp4 Dnch2 Dnchc2 Dync2h1 Fuz Gli1 Gli2 Gli3 Gpr161 Ift122 Ift140 Ift172 Ift52 Ift57 Ift88 Intu Kif3a Kif7 LOC100364088 Mks1 Ofd1 Pdzd6 Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b Ptch Ptch1 Rpgrip1l Sac Slb Smo Smoh Sufu Ttc21b Tulp3 Wdr19 Wdr35	Rattus norvegicus (Norway rat)
G alpha (z) signalling events	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 20 adenylate cyclase	A0A8I5ZV65 A0A8I6AF64 A0A8I6GAY3 A0A8I6GBE3 A0A8I6GLD4 D4A3N4 D4AAI1 F1LQT1 F2Z3T8 G3V8K2 M0R5U4 O35353 P19328 P19627 P21932 P22086 P22909 P26769 P26770 P40146 P43425 P52287 P54311 P54313 P56700 P61954 P62882 P63077 P63219 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Adra2a Adra2b Adra2c Gnaz Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Rgs16 Rgs17 Rgs20 Rgsr	Rattus norvegicus (Norway rat)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Calmodulin-3 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	D4A3N4 F1LQT1 M0R5U4 P09456 P0DP31 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 CaMIII Calm3 Cam3 Camc Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b	Rattus norvegicus (Norway rat)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3 adenylate cyclase	D4A3N4 F1LQT1 M0R5U4 P04897 P08753 P10824 P21932 P26769 P26770 P29348 P38406 P40146 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnal Gnat-3 Gnat3	Rattus norvegicus (Norway rat)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Guanine nucleotide-binding protein G(olf) subunit alpha adenylate cyclase	D4A3N4 F1LQT1 M0R5U4 P21932 P26769 P26770 P38406 P40146 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Gnal	Rattus norvegicus (Norway rat)
Adrenaline,noradrenaline inhibits insulin secretion	Adenylate cyclase type 5 Adenylate cyclase type 6 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 P04897 P10824 P22086 P22909 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63219 Q03343 Q04400	Adcy5 Adcy6 Adra2a Adra2c Gnai-1 Gnai-2 Gnai1 Gnai2 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9	Rattus norvegicus (Norway rat)
Glucagon-type ligand receptors	Gastric inhibitory polypeptide receptor Gastric inhibitory polypeptide Glucagon receptor Glucagon-like peptide 1 receptor Glucagon-like peptide 2 receptor Growth hormone-releasing hormone receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Pituitary adenylate cyclase-activating polypeptide Pro-glucagon Secretin receptor Secretin Somatoliberin VIP peptides Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal polypeptide receptor 2	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 P01283 P06883 P09916 P11384 P13589 P23811 P30082 P30083 P32301 P35000 P43219 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63219 Q02644 Q06145 Q63803 Q9Z0W0	Adcyap1 Gcg Gcgr Ghrh Ghrhr Gip Gipr Glp1r Glp2r Glpr Gnas Gnas1 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Grfr Sct Sctr Vip Vipr1 Vipr2	Rattus norvegicus (Norway rat)
Miscellaneous transport and binding events	Alpha-adducin Beta-adducin Cystinosin, lysosomal cystine transporter Dematin actin binding protein Gamma-adducin Leucine rich repeat containing 8 VRAC subunit B Lysosomal amino acid transporter 1 homolog Magnesium transporter MRS2 homolog, mitochondrial Magnesium transporter protein 1 Mineralization regulator ANKH NIPA magnesium transporter 1 NIPA magnesium transporter 2 NIPA-like domain containing 1 NIPA-like domain containing 2 NIPA-like domain containing 3 NIPA-like domain containing 4 Prolactin-inducible protein homolog Tumor suppressor candidate 3 Volume-regulated anion channel subunit LRRC8A Volume-regulated anion channel subunit LRRC8C Volume-regulated anion channel subunit LRRC8D Volume-regulated anion channel subunit LRRC8E Zinc-alpha-2-glycoprotein	A0A0G2K4T6 A0A8I5ZXT2 A0A8I6GMM8 B0BMY1 D3ZA72 D3ZG79 D3ZKE2 D3ZUV1 D4A758 F1M5J3 O35777 O70417 P58366 Q05764 Q3KRC6 Q498T9 Q4V8I7 Q5U308 Q62847 Q63028 Q63678 Q6AY49 Q9ET09	Add1 Add2 Add3 Ank Ankh Azgp1 Ctns Dmtn Iag2 Lrrc5 Lrrc8 Lrrc8a Lrrc8b Lrrc8c Lrrc8d Lrrc8e Magt1 Mrs2 Mrs2l Nipa1 Nipa2 Nipal1 Nipal2 Nipal3 Nipal4 Pip Pqlc2 Rpt Slc66a1 Tusc3	Rattus norvegicus (Norway rat)
Caspase-mediated cleavage of cytoskeletal proteins	Alpha-adducin Caspase 7 Caspase-3 Caspase-6 Caspase-8 Gelsolin Growth arrest-specific 2 Microtubule-associated protein tau Plectin Sorbin and SH3 domain-containing protein 2 Spectrin alpha chain, non-erythrocytic 1 Vimentin	A0A8I5ZQU7 G3V857 O35397 O35413 P16086 P19332 P30427 P31000 P55213 Q63028 Q68FP1 Q9JHX4	Add1 Argbp2 Casp3 Casp6 Casp7 Casp8 Cpp32 Gas2 Gsn Mapt Mch2 Mtapt Plec Plec1 Sorbs2 Spna2 Spta2 Sptan1 Tau Vim	Rattus norvegicus (Norway rat)
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E2 Adhesion G protein-coupled receptor E5 CD55 molecule (Cromer blood group) Corticoliberin Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor receptor 2 Corticotropin-releasing factor-binding protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Tuberoinfundibular peptide of 39 residues Urocortin 3 Urocortin-2 Urocortin	A0A0G2JSI4 A0A8I5XWT0 A1YKY5 P01143 P04089 P0C172 P13085 P24388 P25961 P35353 P47866 P55090 P70555 Q5Y4N8 Q91WW1	Adgre1 Adgre5 Cd55 Crf2r Crh Crhbp Crhr Crhr1 Crhr2 Emr1 Pth Pth1r Pth2 Pth2r Pthlh Pthr Pthr1 Pthr2 Pthrp Tip39 Tipf39 Ucn Ucn2 Ucn3	Rattus norvegicus (Norway rat)
RA biosynthesis pathway	Alcohol dehydrogenase 1 Aldehyde dehydrogenase 1A1 Aldehyde dehydrogenase 8 family, member A1 Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Cellular retinoic acid-binding protein 1 Cytochrome P450 26A1 Cytochrome P450 26B1 Cytochrome P450, family 26, subfamily C, polypeptide 1 Dehydrogenase/reductase SDR family member 4 Dehydrogenase/reductase SDR family member 9 LRRGT00111 Retinal dehydrogenase 2 Retinaldehyde dehydrogenase 3 Retinol dehydrogenase 10 Retinol dehydrogenase 13 Retinol dehydrogenase 14 Retinol dehydrogenase 7 Short chain dehydrogenase/reductase family 16C, member 5	D3ZFR9 D3ZS85 D3ZUY0 D3ZXY4 D4AAL3 G3V7X8 G3V861 P06757 P51647 P55006 P62966 Q3MHS3 Q63639 Q64563 Q6AYQ2 Q6TUD3 Q80ZF7 Q8K4D8 Q8VD48 Q8VID1	Adh-1 Adh1 Adh2 Adh4 Akr1c1 Akr1c21 Aldh Aldh1a1 Aldh1a2 Aldh1a3 Aldh6 Aldh8a1 Crabp1 Cyp26a1 Cyp26b1 Cyp26c1 Dhrs4 Dhrs9 Hsd17b5 LOC683474 Raldh2 Raldh3 Rdh10 Rdh11 Rdh13 Rdh14 Rdh3 Rdh7 Sdr16c5 eRolDH	Rattus norvegicus (Norway rat)
Calcitonin-like ligand receptors	Calcitonin gene-related peptide 2 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Calcitonin Islet amyloid polypeptide Pro-adrenomedullin Protein ADM2 Receptor activity-modifying protein 1 Receptor activity-modifying protein 2 Receptor activity-modifying protein 3	P01257 P10093 P12969 P32214 P43145 P61312 Q63118 Q9JHJ1 Q9JJ73 Q9JJ74	Adm Adm2 Am2 Calc Calca Calcb Calcr Calcrl Cgrpr Iapp Ramp1 Ramp2 Ramp3	Rattus norvegicus (Norway rat)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Cystathionine gamma-lyase Cysteine dioxygenase type 1 Flavin-containing monooxygenase 1 Glutamate decarboxylase-like 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	A0A8I5ZWY4 A0A8I6AWC8 P18757 P21816 P24329 P36365 P97532 P97615	Ado Cdo1 Cth Fmo-1 Fmo1 Gadl1 Mpst Trx2 Tst Txn2	Rattus norvegicus (Norway rat)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P25099 P28647 P29276 P30543	Adora1 Adora2a Adora2b Adora3	Rattus norvegicus (Norway rat)
Glycolysis	ADP-dependent glucokinase ATP-dependent 6-phosphofructokinase, liver type ATP-dependent 6-phosphofructokinase, muscle type ATP-dependent 6-phosphofructokinase, platelet type Beta-enolase Enolase 4 Fructose-bisphosphate aldolase A Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase C Gamma-enolase Glucosamine-6-phosphate isomerase Glucosamine-6-phosphate isomerase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Hexokinase-1 Hexokinase-2 Hexokinase-3 Hexokinase-4 Phosphoglucomutase 2-like 1 Phosphoglycerate kinase 1 Phosphoglycerate kinase Phosphoglycerate mutase 1 Phosphoglycerate mutase 2 Phosphoglycerate mutase Pyruvate kinase PKLR Pyruvate kinase Triosephosphate isomerase Triosephosphate isomerase hexokinase	A0A8I5ZVI4 A0A8I6AB87 A0A8I6AN31 B5DEZ6 D3Z955 F1LUV3 G3V784 M0R3X7 M0RD14 P00884 P04797 P05065 P05708 P07323 P09117 P12928 P15429 P16290 P16617 P17712 P25113 P27881 P27926 P30835 P47858 P47860 P48500 Q5XIV1 Q6P6V0 Q7TP58 Q9ESV6	Adpgk Aldoa Aldob Aldoc Bpgm ENSRNOG00000066746 Eno-2 Eno-3 Eno2 Eno3 Eno4 Gapd Gapd-s Gapdh Gapdhs Gapds Gck Gnpda1 Gnpda2 Gpi Hk1 Hk2 Hk3 Hkdc1 LOC100362738 Pfk-l Pfk-m Pfkc Pfkl Pfkm Pfkp Pgam1 Pgam2 Pgk-1 Pgk1 Pgk2 Pgm2l1 Pklr Pkml1 RGD1563601 Tpi1 Tpi1l2	Rattus norvegicus (Norway rat)	G58161NS
Downregulation of SMAD2/3:SMAD4 transcriptional activity	E3 ubiquitin-protein ligase HECT-type E3 ubiquitin transferase Histone deacetylase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Nuclear receptor co-repressor 2 Poly [ADP-ribose] polymerase 1 Polyubiquitin-B Polyubiquitin-C Protein ATP1B4 Protein phosphatase 1A SKI-like proto-oncogene SNW domain-containing protein 1 Ski oncogene TGFB-induced factor homeobox 1 Tripartite motif-containing 33 Ubiquitin B-like Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JU91 A0A0G2K628 A0A8I5Y0P5 A0A8I5ZP60 A0A8I5ZTL5 A0A8I6A5Y3 A0A8I6AEH7 D3ZDK2 D3ZUK4 D3ZWL1 O70436 O70437 P0CG51 P20650 P21708 P27008 P61078 P62982 P63086 P84025 Q4QQW4 Q63429 Q9R193	Adprt Atp1b4 Erk1 Erk2 Hdac1 LOC100360645 Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Ncor2 Nedd4l Parp1 Pp2c1 Ppm1a Pppm1a Prkm1 Prkm3 Rps27a Ski Skil Smad2 Smad3 Smad4 Smurf2 Snw1 Tgif1 Trim33 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2d1 Ube2d3	Rattus norvegicus (Norway rat)
Formation of Incision Complex in GG-NER	CDK-activating kinase assembly factor MAT1 Centrin 2 Chromodomain helicase DNA binding protein 1-like Cullin 4A Cullin 4B Cyclin-H Cyclin-dependent kinase 7 (Fragment) DNA damage-binding protein 1 DNA damage-binding protein 2 E3 SUMO-protein ligase PIAS3 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC excision repair 4, endonuclease catalytic subunit ERCC excision repair 5, endonuclease General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 Poly (ADP-ribose) polymerase 2 Poly [ADP-ribose] polymerase 1 Polyubiquitin-B Polyubiquitin-C Protein inhibitor of activated STAT, 1 Replication protein A 32 kDa subunit Replication protein A subunit Replication protein A3 Ring-box 1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 UV excision repair protein RAD23 homolog B UV excision repair protein RAD23 Ubiquitin B-like Ubiquitin carboxyl-terminal hydrolase Ubiquitin-ribosomal protein eS31 fusion protein XPA, DNA damage recognition and repair factor XPC complex subunit, DNA damage recognition and repair factor	A0A096MKI6 A0A0G2JUC8 A0A0G2JWQ0 A0A0G2K4S7 A0A8I5ZYW5 A0A8I6A5Y3 A0A8I6AH26 A0A8I6AJT7 A0A8I6G6T5 A0JN27 D3ZAQ9 D3ZEI7 D3ZK73 D3ZR08 D3ZT95 D4A3D8 D4A845 F7EX11 F7FJT3 F7FNG5 G3V749 G3V9W0 O70260 P0CG51 P27008 P51952 P61959 P62982 P63281 Q4G005 Q4KMA2 Q561R7 Q5I0H3 Q5XIF4 Q63429 Q63528 Q7TP21 Q9ESW0 Q9R1A0	Adprt Cak Cak1 Ccnh Cdk7 Cetn2 Chd1l Cul4a Cul4b Ddb1 Ddb2 Ercc1 Ercc2 Ercc3 Ercc4 Ercc5 Gtf2h1 Gtf2h2 Gtf2h3 Gtf2h5 LOC100360645 Mnat1 Mo15 Parp1 Parp2 Pias1 Pias3 Rad23a Rad23b Rbx1 Rpa1 Rpa2 Rpa3 Rps27a Smt3a Smt3h2 Sumo1 Sumo2 Sumo3 Uba80 Ubb Ubbl1 Ubc Ubce9 Ubcep1 Ubcl1 Ube2i Usp45 Xpa Xpc	Rattus norvegicus (Norway rat)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor	P10608 P15823 P18090 P19328 P22086 P22909 P23944 P26255 P43140	Adra1a Adra1b Adra1c Adra1d Adra2a Adra2b Adra2c Adrb1 Adrb1r Adrb2 Adrb2r Adrb3 Adrb3r	Rattus norvegicus (Norway rat)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	P19328 P22086 P22909	Adra2a Adra2b Adra2c	Rattus norvegicus (Norway rat)
G alpha (s) signalling events	3',5'-cyclic-AMP phosphodiesterase 4A 3',5'-cyclic-AMP phosphodiesterase 4C (Fragment) 3',5'-cyclic-AMP phosphodiesterase 4D Beta-2 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 5 G protein-coupled receptor kinase 6 High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (Fragment) Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B	A0A8I5ZTX5 A0A8I5ZWQ4 A0A8I6A416 O08593 P10608 P14270 P14644 P26817 P26819 P29066 P29067 P54748 P97711 Q01062 Q01066 Q62833 Q62865 Q63085 Q76KC6 Q8VID6 Q9QYJ6	Adrb2 Adrb2r Adrbk1 Adrbk2 Arrb1 Arrb2 Dpde1 Gprk5 Gprk6 Grk2 Grk3 Grk5 Grk6 Pde10a Pde11a Pde1a Pde1b Pde1b1 Pde2a Pde3a Pde3b Pde4a Pde4c Pde4d Pde7a Pde7b Pde8a Pde8b RNPDE8A	Rattus norvegicus (Norway rat)
Calmodulin induced events	Beta-adrenergic receptor kinase 1 Calmodulin-3 Protein kinase C alpha type Protein kinase C delta type Protein kinase C gamma type	P05696 P09215 P0DP31 P26817 P63319	Adrbk1 CaMIII Calm3 Cam3 Camc Grk2 Pkca Pkcc Pkcd Pkcg Prkca Prkcc Prkcd Prkcg	Rattus norvegicus (Norway rat)
Activation of SMO	Beta-adrenergic receptor kinase 1 Casein kinase I isoform alpha Protein smoothened	P26817 P97633 P97698	Adrbk1 Csnk1a1 Grk2 Smo Smoh	Rattus norvegicus (Norway rat)

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