GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **376 - 400** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism
Activation of Ca-permeable Kainate Receptor	Calmodulin-3 Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Glutamate receptor ionotropic, kainate 1 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate 3 Glutamate receptor ionotropic, kainate 4 Glutamate receptor ionotropic, kainate 5 Neurocalcin-delta	P0DP31 P22756 P31016 P42260 P42264 Q01812 Q5PQN0 Q62696 Q62936 Q63273	CaMIII Calm3 Cam3 Camc Dlg1 Dlg3 Dlg4 Dlgh1 Dlgh3 Dlgh4 Glur5 Glur6 Glur7 Grik1 Grik2 Grik3 Grik4 Grik5 Ncald Psd95	Rattus norvegicus (Norway rat)
RHO GTPases activate PAKs	Calmodulin-3 Cell division control protein 42 homolog Filamin A LIM domain kinase 1 Merlin (Fragment) Myosin heavy chain 14 Myosin light chain kinase, smooth muscle Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein phosphatase PP1-beta catalytic subunit	A0A8I5ZV49 A0A8I6AUI8 D3ZFU9 D3ZIC4 F1LNF0 P0DP31 P18666 P35465 P53669 P62142 Q10728 Q62812 Q62829 Q63648 Q64122 Q64303 Q6RUV5 Q8CFN2 Q9JLT0	CaMIII Calm3 Cam3 Camc Cdc42 Flna LOC685883 Limk Limk1 Mbs Mrlc2 Mrlcb Myh10 Myh14 Myh9 Myl12b Myl6 Myl9 Mylc2b Mylk Mypt1 Myrl2 Nf2 Pak1 Pak2 Pak3 Ppp1cb Ppp1r12a Ppp1r12b Rac Rac1	Rattus norvegicus (Norway rat)
CaMK IV-mediated phosphorylation of CREB	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type IV Calmodulin-3	O88831 P0DP31 P13234 P97756	CaMIII Calm3 Cam3 Camc Camk4 Camkk1 Camkk2	Rattus norvegicus (Norway rat)
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type IV Calmodulin-3	O88831 P0DP31 P13234 P97756	CaMIII Calm3 Cam3 Camc Camk4 Camkk1 Camkk2	Rattus norvegicus (Norway rat)
Activation of RAC1 downstream of NMDARs	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type 1 Calmodulin-3	O88831 P0DP31 P97756 Q63450	CaMIII Calm3 Cam3 Camc Camk1 Camkk1 Camkk2	Rattus norvegicus (Norway rat)
CLEC7A (Dectin-1) induces NFAT activation	Calcineurin subunit B type 1 Calmodulin-3 Nuclear factor of activated T-cells 1 Nuclear factor of activated T-cells 2 Nuclear factor of activated T-cells, cytoplasmic 3 Protein phosphatase 3 catalytic subunit alpha Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	A0A0G2JTY4 D3ZE20 D4A0I8 P0DP31 P20651 P63100 P63329	CaMIII Calm3 Calna Cam3 Camc Cna2 Cnb Nfat4 Nfatc1 Nfatc2 Nfatc3 Ppp3ca Ppp3cb Ppp3r1 RGD1560225	Rattus norvegicus (Norway rat)
Calcineurin activates NFAT	Calcineurin subunit B type 1 Calmodulin-3 Nuclear factor of activated T-cells 1 Nuclear factor of activated T-cells 2 Nuclear factor of activated T-cells, cytoplasmic 3 Peptidyl-prolyl cis-trans isomerase FKBP1A Protein phosphatase 3 catalytic subunit alpha Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	A0A0G2JTY4 D3ZE20 D4A0I8 P0DP31 P20651 P63100 P63329 Q62658	CaMIII Calm3 Calna Cam3 Camc Cna2 Cnb Fkbp1 Fkbp1a Nfat4 Nfatc1 Nfatc2 Nfatc3 Ppp3ca Ppp3cb Ppp3r1 RGD1560225	Rattus norvegicus (Norway rat)
Ca2+ pathway	Calcineurin subunit B type 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calmodulin-3 Catenin beta-1 Frizzled class receptor 3 Frizzled-2 Frizzled-4 Frizzled-5 Frizzled-6 G protein subunit alpha transducin 2 GTPase KRas Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Lymphoid enhancer-binding factor 1 Mitogen-activated protein kinase kinase kinase 7 Nuclear factor of activated T-cells 1 Phosphodiesterase Phosphodiesterase Protein Wnt-5a Protein Wnt Protein phosphatase 3 catalytic subunit alpha Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Serine/threonine-protein kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Transcription factor 7 like 2	A0A8I6A9A2 A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D3Z8C9 D3ZDI8 D3ZE20 D3ZSZ3 D4AA42 D4AAI1 F2Z3T8 G3V6L1 G3V819 G3V8K2 M0R4R9 M0RCN5 O35353 P08644 P0C8E4 P0DP31 P11275 P20651 P43425 P52287 P54311 P54313 P59215 P61954 P62882 P63077 P63100 P63219 P63329 Q08464 Q8CHL0 Q9QXN1 Q9QXQ7 Q9QZH0 Q9WU82	CaMIII Calm3 Calna Cam3 Camc Camk2a Catnb Cna2 Cnb Ctnnb1 Fzd2 Fzd3 Fzd4 Fzd5 Fzd6 Gna0 Gnao Gnao1 Gnat2 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Kras Kras2 Lef1 Map3k7 Nfatc1 Nlk Pde6a Pde6b Pde6g Ppp3ca Ppp3cb Ppp3r1 RGD1560225 Tcf7l2 Wnt-5a Wnt11 Wnt5a	Rattus norvegicus (Norway rat)
Reversible hydration of carbon dioxide	Carbonic anhydrase 14 Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 3 Carbonic anhydrase 4 Carbonic anhydrase 5A, mitochondrial Carbonic anhydrase 5B, mitochondrial Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase	A0A8I6AHH2 B0BNN3 B5DFG6 F1LQ08 F7FAJ9 F7FL00 P14141 P27139 P43165 P48284 Q66HG6	Ca1 Ca2 Ca3 Ca4 Ca5 Ca5a Ca5b Car1 Car12 Car13 Car14 Car5b Car6 Car9	Rattus norvegicus (Norway rat)
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 G protein subunit alpha transducin 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit gamma Phosphodiesterase Phosphodiesterase Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin	A0A8I5ZN27 D3Z8C9 D3ZDI8 D3ZSS5 D4AAI1 M0R4R9 P51489 P54311 Q62927	CNCG2 CNCG3L CNCG4 Cncg Cncg1 Cnga1 Cngb1 Gnat1 Gnb1 Gngt1 Pde6a Pde6b Pde6g RCNC2 Rho	Rattus norvegicus (Norway rat)
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-3 Calmodulin-lysine N-methyltransferase Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 G protein subunit alpha transducin 1 G protein-coupled receptor kinase 4 Glycylpeptide N-tetradecanoyltransferase 1 Glycylpeptide N-tetradecanoyltransferase Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 2 Methionine aminopeptidase 2 Methionine aminopeptidase Phosphodiesterase Phosphodiesterase Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Recoverin Regulator of G protein signaling 9 binding protein Regulator of G-protein signaling 9 Retinal guanylyl cyclase 1 Retinal guanylyl cyclase 2 Rhodopsin kinase GRK1 Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin S-arrestin Serine/threonine-protein phosphatase with EF-hands 1	A0A8I5ZLL5 A0A8I5ZN27 B0K012 D3Z8C9 D3ZC97 D3ZDI8 D3ZE72 D3ZID7 D3ZII9 D3ZSS5 D4AAI1 G3V6G4 M0R4R9 P0DP31 P15887 P38062 P49805 P51489 P51840 P51842 P62882 P70507 Q02293 Q04631 Q3SWT6 Q62927 Q63651 Q8K1Q0	CNCG2 CNCG3L CNCG4 CaMIII Calm3 Cam3 Camc Camkmt Clnmt Cncg Cncg1 Cnga1 Cngb1 Fnta Fntb Gnat1 Gnb5 Gngt1 Gprk2l Grk1 Grk4 Guc2e Guc2f Guca1a Guca1b Gucy2d Gucy2e Gucy2f Metap1 Metap2 Mnpep Nmt1 Nmt2 P67eif2 Pde6a Pde6b Pde6g Ppef1 RCNC2 Rcvrn Rgs9 Rgs9bp Rho Rhok Sag	Rattus norvegicus (Norway rat)
Terminal pathway of complement	Complement C5 Complement component C6	P08650 Q811M5	C5 C6	Rattus norvegicus (Norway rat)
Degradation of DVL	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 Dishevelled-binding antagonist of beta-catenin 1 HECT-type E3 ubiquitin transferase Kelch-like protein 12 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 Segment polarity protein dishevelled homolog DVL-1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6AG92 A0A8I6GKX7 B0BN93 B5DF89 D3ZB71 D4A3W8 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q8R2H4 Q9JHW0 Q9WTV5 Q9WVB9 Q9Z2X3	C3ip1 Cul3 Dact1 Dvl1 Dvl2 Dvl3 Hecw1 Klhl12 LOC100360645 LOC100360846 LOC100361515 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Alternative complement activation	Complement C3	P01026	C3	Rattus norvegicus (Norway rat)
Activation of C3 and C5	Complement C2 Complement C3 Complement C4 Complement C4B (Chido blood group) Complement C5	A0A8J8YKQ8 P01026 P08649 P08650 Q6MG90	C2 C3 C4 C4a C4b C5 Cfb	Rattus norvegicus (Norway rat)
Serotonin Neurotransmitter Release Cycle	Complexin-1 Liprin-alpha-3 Liprin-alpha-4 (Fragment) PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2	A0A1B0GWS0 A0A8I6AK94 O70441 P09951 P21707 P32851 P60881 P61765 P63012 P63041 P63045 Q01827 Q62769 Q63537 Q91Z79 Q91Z80 Q9JIR0 Q9JIR4	Bzrap1 Cplx1 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Rab3a Rbp1 Rim1 Rims1 Sap Slc18a2 Snap Snap25 Stx1a Stxbp1 Svat Syb2 Syn1 Syn2 Syn3 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Vmat2	Rattus norvegicus (Norway rat)
Norepinephrine Neurotransmitter Release Cycle	Amine oxidase [flavin-containing] A Complexin-1 Liprin-alpha-3 Liprin-alpha-4 (Fragment) PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2	A0A1B0GWS0 A0A8I6AK94 P21396 P21707 P32851 P60881 P61765 P63012 P63041 P63045 Q01827 Q62769 Q63089 Q91Z79 Q91Z80 Q9JIR0 Q9JIR4 Q9R0W2	Bzrap1 Cplx1 Maoa Oct1 Oct2 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Rab3a Rbp1 Rim1 Rims1 Sap Slc18a2 Slc22a1 Slc22a2 Snap Snap25 Stx1a Stxbp1 Svat Syb2 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Vmat2	Rattus norvegicus (Norway rat)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 High affinity choline transporter 1 Liprin-alpha-3 Liprin-alpha-4 (Fragment) PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular acetylcholine transporter	A0A1B0GWS0 A0A8I6AK94 P21707 P32738 P32851 P60881 P61765 P63012 P63041 P63045 Q62666 Q62769 Q91Z79 Q91Z80 Q9JIR0 Q9JIR4 Q9JMD7	Bzrap1 Chat Cht1 Cplx1 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Rab3a Rbp1 Rim1 Rims1 Sap Slc18a3 Slc5a7 Snap Snap25 Stx1a Stxbp1 Syb2 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vacht Vamp2 Vat	Rattus norvegicus (Norway rat)
Pyrimidine catabolism	5', 3'-nucleotidase, cytosolic 5',3'-nucleotidase, mitochondrial 5'-nucleotidase, cytosolic IA 5'-nucleotidase 5'-nucleotidase Beta-ureidopropionase Dihydropyrimidinase Dihydropyrimidine dehydrogenase [NADP(+)] Thymidine phosphorylase Uridine phosphorylase Uridine phosphorylase	A0A8I5ZYY7 A0A8I6AHB0 D3ZWR1 D4A5J2 D4A9N9 F7F0D5 O89000 P21588 Q03248 Q5FVR2 Q63150	Bup1 DPD Dpyd Dpys Ecgf1 Nt5 Nt5c Nt5c1a Nt5c3a Nt5e Nt5m Nte Tymp Upb1 Upp1 Upp2	Rattus norvegicus (Norway rat)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 Glycogen synthase kinase-3 beta Nuclear factor erythroid 2-related factor 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6G2R1 B0BN93 F1LMQ3 F1LMZ8 F7FGV7 G3V6W6 G3V8G2 O54968 O88761 P0CG51 P17220 P18266 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Cul1 Gsk3b LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Nfe2l2 Nrf2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Degradation of GLI1 by the proteasome	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 E3 ubiquitin-protein ligase GLI family zinc finger 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein numb homolog Ring-box 1 S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZZU1 A0A8I6A5Y3 A0A8I6A606 A0A8I6G2R1 B0BN93 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V6X8 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q2LC84 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Cul1 Gli1 Itch LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Numb Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sufu Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Prolactin receptor signaling	Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 Growth hormone receptor Prolactin receptor Prolactin Ring-box 1 S-phase kinase-associated protein 1 SH2B adapter protein 1 Somatotropin Tyrosine-protein kinase JAK2	A0A0G2JUC8 A0A8I5Y0H0 A0A8I6G2R1 P01237 P01244 P05710 P16310 Q62689 Q62985 Q6PEC4	Btrc Cul1 Gh Gh1 Ghr Jak2 Prl Prlr Rbx1 Sh2-b Sh2b1 Sh2bpsm1 Skp1 Skp1a	Rattus norvegicus (Norway rat)
GLI3 is processed to GLI3R by the proteasome	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Casein kinase I isoform alpha Cullin 1 GLI family zinc finger 3 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6A606 A0A8I6G2R1 B0BN93 F1LMQ3 F1LMZ8 F1M6I7 F1M9H1 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18266 P18420 P18421 P18422 P21670 P27791 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 P68182 P97633 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Csnk1a1 Cul1 Gli3 Gsk3b LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Pkacb Prkaca Prkacb Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sufu Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Dectin-1 mediated noncanonical NF-kB signaling	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit Nuclear factor kappa B subunit 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta RELB proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-conjugating enzyme E2M Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZYZ8 A0A8I6A5Y3 A0A8I6ANR6 A0A8I6G2R1 A0A8I6G6F3 A0A8I6GIW9 B0BN93 D3ZTD1 D4A8H1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q99MI7 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Chuk Cul1 Fbxw11 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Map3k14 Mecl1 Mss1 Nfkb2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Relb Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba3 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube1c Ube2m	Rattus norvegicus (Norway rat)
NIK-->noncanonical NF-kB signaling	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit Nuclear factor kappa B subunit 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta RELB proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-conjugating enzyme E2M Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZYZ8 A0A8I6A5Y3 A0A8I6ANR6 A0A8I6G2R1 A0A8I6G6F3 A0A8I6GIW9 B0BN93 D3ZTD1 D4A8H1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q99MI7 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Chuk Cul1 Fbxw11 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Map3k14 Mecl1 Mss1 Nfkb2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Relb Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba3 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube1c Ube2m	Rattus norvegicus (Norway rat)

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