luminal breast carcinoma A

Summary
Synonym
  • Luminal A Breast Carcinoma
Definition
A breast carcinoma that is characterized by high expression of genes characteristic of luminal epithelial cells, including estrogen receptor (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3.
Super Class
breast carcinoma
External Links
Disease Ontology
DOID:0060548
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
31 ACACA acetyl-CoA carboxylase alpha
142 PARP1 poly(ADP-ribose) polymerase 1
1012 CDH13 cadherin 13
1588 CYP19A1 cytochrome P450 family 19 subfamily A member 1
2194 FASN fatty acid synthase
3161 HMMR hyaluronan mediated motility receptor
3418 IDH2 isocitrate dehydrogenase (NADP(+)) 2
5162 PDHB pyruvate dehydrogenase E1 subunit beta
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5335 PLCG1 phospholipase C gamma 1

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024