osteoporosis

Summary
Definition
A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
Super Class
bone resorption disease
Disease Ontology
DOID:11476
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 21 - 30 of 44 in total
Gene ID Gene Symbol Description Source
3552 IL1A interleukin 1 alpha
3557 IL1RN interleukin 1 receptor antagonist
3667 IRS1 insulin receptor substrate 1
3952 LEP leptin
3953 LEPR leptin receptor
4041 LRP5 LDL receptor related protein 5
4261 CIITA class II major histocompatibility complex transactivator
4318 MMP9 matrix metallopeptidase 9
4609 MYC MYC proto-oncogene, bHLH transcription factor
4982 TNFRSF11B TNF receptor superfamily member 11b
Displaying entries 31 - 38 of 38 in total
Gene ID Gene Symbol Description Source
21934 Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator
21938 Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b
21943 Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11
26416 Mapk14 mitogen-activated protein kinase 14
102866 Pls3 plastin 3 (T-isoform)
105348 Golm1 golgi membrane protein 1
384783 Irs2 insulin receptor substrate 2
666279 Dspp dentin sialophosphoprotein
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
24241 Calca calcitonin-related polypeptide alpha
24310 Ace angiotensin I converting enzyme
24483 Igf2 insulin-like growth factor 2
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
24536 Lepr leptin receptor
24577 Myc MYC proto-oncogene, bHLH transcription factor
24787 Sod2 superoxide dismutase 2
24890 Esr1 estrogen receptor 1
25149 Esr2 estrogen receptor 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
33432 dpp decapentaplegic
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
30686 myca MYC proto-oncogene, bHLH transcription factor a
393141 mycb MYC proto-oncogene, bHLH transcription factor b
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397873 bmp2.L bone morphogenetic protein 2 L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175942 pdfr-1 Calcitonin receptor-like protein 1
179068 dbl-1 Protein dbl-1
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
Displaying 1 entry
Gene ID Gene Symbol Description Source
856014 GLR1 glutathione-disulfide reductase GLR1

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Last updated: December 9, 2024