major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 161 - 170 of 217 in total
Gene ID Gene Symbol Description Source
10858 CYP46A1 cytochrome P450 family 46 subfamily A member 1
10908 PNPLA6 patatin like phospholipase domain containing 6
11253 MAN1B1 mannosidase alpha class 1B member 1
11282 MGAT4B alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
11332 ACOT7 acyl-CoA thioesterase 7
22901 ARSG arylsulfatase G
22933 SIRT2 sirtuin 2
23236 PLCB1 phospholipase C beta 1
23483 TGDS TDP-glucose 4,6-dehydratase
23583 SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024